| NetPath: a public resource of curated signal transduction pathways K Kandasamy, SS Mohan, R Raju, S Keerthikumar, GSS Kumar, ... Genome biology 11, 1-9, 2010 | 525 | 2010 |
| Studying multisite binary and ternary protein interactions by global analysis of isothermal titration calorimetry data in SEDPHAT: application to adaptor protein complexes in … JCD Houtman, PH Brown, B Bowden, H Yamaguchi, E Appella, ... Protein Science 16 (1), 30-42, 2007 | 358 | 2007 |
| Oligomerization of signaling complexes by the multipoint binding of GRB2 to both LAT and SOS1 JCD Houtman, H Yamaguchi, M Barda-Saad, A Braiman, B Bowden, ... Nature structural & molecular biology 13 (9), 798-805, 2006 | 241 | 2006 |
| Early phosphorylation kinetics of proteins involved in proximal TCR-mediated signaling pathways JCD Houtman, RA Houghtling, M Barda-Saad, Y Toda, LE Samelson The Journal of Immunology 175 (4), 2449-2458, 2005 | 143 | 2005 |
| Binding specificity of multiprotein signaling complexes is determined by both cooperative interactions and affinity preferences JCD Houtman, Y Higashimoto, N Dimasi, S Cho, H Yamaguchi, ... Biochemistry 43 (14), 4170-4178, 2004 | 130 | 2004 |
| Comparison of T cell receptor-induced proximal signaling and downstream functions in immortalized and primary T cells RR Bartelt, N Cruz-Orcutt, M Collins, JCD Houtman PloS one 4 (5), e5430, 2009 | 123 | 2009 |
| Basis of substrate binding and conservation of selectivity in the CLC family of channels and transporters A Picollo, M Malvezzi, JCD Houtman, A Accardi Nature structural & molecular biology 16 (12), 1294-1301, 2009 | 122 | 2009 |
| Cooperative interactions at the SLP‐76 complex are critical for actin polymerization M Barda‐Saad, N Shirasu, MH Pauker, N Hassan, O Perl, A Balbo, ... The EMBO journal 29 (14), 2315-2328, 2010 | 119 | 2010 |
| Thiopurine methyltransferase pharmacogenetics. Cloning of human liver cDNA and a processed pseudogene on human chromosome 18q21. 1. D Lee, C Szumlanski, J Houtman, R Honchel, K Rojas, J Overhauser, ... Drug metabolism and disposition 23 (3), 398-405, 1995 | 90 | 1995 |
| Characterization of the N-acetyl-5-neuraminic acid-binding site of the extracytoplasmic solute receptor (SiaP) of nontypeable Haemophilus influenzae strain 2019 JW Johnston, NP Coussens, S Allen, JCD Houtman, KH Turner, A Zaleski, ... Journal of Biological Chemistry 283 (2), 855-865, 2008 | 86 | 2008 |
| A calcineurin docking motif (LXVP) in dynamin-related protein 1 contributes to mitochondrial fragmentation and ischemic neuronal injury AM Slupe, RA Merrill, KH Flippo, MA Lobas, JCD Houtman, S Strack Journal of Biological Chemistry 288 (17), 12353-12365, 2013 | 84 | 2013 |
| Glycerol Monolaurate (GML) inhibits human T cell signaling and function by disrupting lipid dynamics MS Zhang, A Sandouk, JCD Houtman Scientific reports 6 (1), 30225, 2016 | 78 | 2016 |
| Growth hormone-induced alteration in ErbB-2 phosphorylation status in 3T3-F442A fibroblasts SO Kim, JCD Houtman, J Jiang, JM Ruppert, PJ Bertics, SJ Frank Journal of Biological Chemistry 274 (50), 36015-36024, 1999 | 68 | 1999 |
| The proliferating cell nuclear antigen (PCNA)-interacting protein (PIP) motif of DNA polymerase η mediates its interaction with the C-terminal domain of Rev1 EM Boehm, KT Powers, CM Kondratick, M Spies, JCD Houtman, ... Journal of Biological Chemistry 291 (16), 8735-8744, 2016 | 61 | 2016 |
| Examining multiprotein signaling complexes from all angles: The use of complementary techniques to characterize complex formation at the adapter protein, linker for activation … JCD Houtman, M Barda‐Saad, LE Samelson The FEBS journal 272 (21), 5426-5435, 2005 | 59 | 2005 |
| Multipoint binding of the SLP-76 SH2 domain to ADAP is critical for oligomerization of SLP-76 signaling complexes in stimulated T cells NP Coussens, R Hayashi, PH Brown, L Balagopalan, A Balbo, I Akpan, ... Molecular and cellular biology 33 (21), 4140-4151, 2013 | 54 | 2013 |
| Exposure of human CD4 T cells to IL-12 results in enhanced TCR-induced cytokine production, altered TCR signaling, and increased oxidative metabolism A Vacaflores, NM Chapman, JT Harty, MJ Richer, JCD Houtman PloS one 11 (6), e0157175, 2016 | 53 | 2016 |
| 3-Picolyl azide adenine dinucleotide as a probe of femtosecond to picosecond enzyme dynamics S Dutta, YL Li, W Rock, JCD Houtman, A Kohen, CM Cheatum The Journal of Physical Chemistry B 116 (1), 542-548, 2012 | 50 | 2012 |
| Polymicrobial sepsis influences NK-cell-mediated immunity by diminishing NK-cell-intrinsic receptor-mediated effector responses to viral ligands or infections IJ Jensen, CS Winborn, MG Fosdick, P Shao, MM Tremblay, Q Shan, ... PLoS pathogens 14 (10), e1007405, 2018 | 49 | 2018 |
| Functions of the FAK family kinases in T cells: beyond actin cytoskeletal rearrangement NM Chapman, JCD Houtman Immunologic research 59, 23-34, 2014 | 48 | 2014 |
