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Shanshan Pei, PhD, Principal Investigator
Shanshan Pei, PhD, Principal Investigator
Zhejiang University
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Title
Cited by
Cited by
Year
BCL-2 inhibition targets oxidative phosphorylation and selectively eradicates quiescent human leukemia stem cells
ED Lagadinou, A Sach, K Callahan, RM Rossi, SJ Neering, ...
Cell stem cell 12 (3), 329-341, 2013
12132013
Venetoclax with azacitidine disrupts energy metabolism and targets leukemia stem cells in patients with acute myeloid leukemia
DA Pollyea, BM Stevens, CL Jones, A Winters, S Pei, M Minhajuddin, ...
Nature medicine 24 (12), 1859-1866, 2018
5742018
Leukemic stem cells evade chemotherapy by metabolic adaptation to an adipose tissue niche
H Ye, B Adane, N Khan, T Sullivan, M Minhajuddin, M Gasparetto, ...
Cell stem cell 19 (1), 23-37, 2016
4682016
Inhibition of amino acid metabolism selectively targets human leukemia stem cells
CL Jones, BM Stevens, A D'Alessandro, JA Reisz, R Culp-Hill, T Nemkov, ...
Cancer cell 34 (5), 724-740. e4, 2018
4422018
Monocytic subclones confer resistance to venetoclax-based therapy in patients with acute myeloid leukemia
S Pei, DA Pollyea, A Gustafson, BM Stevens, M Minhajuddin, R Fu, ...
Cancer discovery 10 (4), 536-551, 2020
2952020
AMPK/FIS1-mediated mitophagy is required for self-renewal of human AML stem cells
S Pei, M Minhajuddin, B Adane, N Khan, BM Stevens, SC Mack, S Lai, ...
Cell stem cell 23 (1), 86-100. e6, 2018
2202018
Targeting aberrant glutathione metabolism to eradicate human acute myelogenous leukemia cells
S Pei, M Minhajuddin, KP Callahan, M Balys, JM Ashton, SJ Neering, ...
Journal of Biological Chemistry 288 (47), 33542-33558, 2013
2132013
The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation
HA Zahreddine, B Culjkovic-Kraljacic, S Assouline, P Gendron, ...
Nature 511 (7507), 90-93, 2014
1992014
Fatty acid metabolism underlies venetoclax resistance in acute myeloid leukemia stem cells
BM Stevens, CL Jones, DA Pollyea, R Culp-Hill, A D’Alessandro, ...
Nature cancer 1 (12), 1176-1187, 2020
1732020
Nicotinamide metabolism mediates resistance to venetoclax in relapsed acute myeloid leukemia stem cells
CL Jones, BM Stevens, DA Pollyea, R Culp-Hill, JA Reisz, T Nemkov, ...
Cell stem cell 27 (5), 748-764. e4, 2020
1532020
Cysteine depletion targets leukemia stem cells through inhibition of electron transport complex II
CL Jones, BM Stevens, A D’Alessandro, R Culp-Hill, JA Reisz, S Pei, ...
Blood, The Journal of the American Society of Hematology 134 (4), 389-394, 2019
1262019
Venetoclax and azacitidine compared with induction chemotherapy for newly diagnosed patients with acute myeloid leukemia
EM Cherry, D Abbott, M Amaya, C McMahon, M Schwartz, J Rosser, ...
Blood advances 5 (24), 5565-5573, 2021
1042021
The mitotic checkpoint kinase NEK2A regulates kinetochore microtubule attachment stability
J Du, X Cai, J Yao, X Ding, Q Wu, S Pei, K Jiang, Y Zhang, W Wang, Y Shi, ...
Oncogene 27 (29), 4107-4114, 2008
912008
The hematopoietic oxidase NOX2 regulates self-renewal of leukemic stem cells
B Adane, H Ye, N Khan, S Pei, M Minhajuddin, BM Stevens, CL Jones, ...
Cell reports 27 (1), 238-254. e6, 2019
732019
The STAT3-MYC axis promotes survival of leukemia stem cells by regulating SLC1A5 and oxidative phosphorylation
ML Amaya, A Inguva, S Pei, C Jones, A Krug, H Ye, M Minhajuddin, ...
Blood, The Journal of the American Society of Hematology 139 (4), 584-596, 2022
612022
SomVarIUS: somatic variant identification from unpaired tissue samples
KS Smith, VK Yadav, S Pei, DA Pollyea, CT Jordan, S De
Bioinformatics 32 (6), 808-813, 2016
552016
Melampomagnolide B: a new antileukemic sesquiterpene
S Nasim, SS Pei, FK Hagen, CT Jordan, PA Crooks
Bioorganic & medicinal chemistry 19 (4), 1515-1519, 2011
492011
Inhibition of amino acid metabolism selectively targets human leukemia stem cells
CL Jones, BM Stevens, A D’Alessandro, JA Reisz, R Culp-Hill, T Nemkov, ...
Cancer Cell 35 (2), 333-335, 2019
472019
Rational design of a parthenolide-based drug regimen that selectively eradicates acute myelogenous leukemia stem cells
S Pei, M Minhajuddin, A D'Alessandro, T Nemkov, BM Stevens, B Adane, ...
Journal of Biological Chemistry 291 (42), 21984-22000, 2016
392016
Targeted therapy for a subset of acute myeloid leukemias that lack expression of aldehyde dehydrogenase 1A1
M Gasparetto, S Pei, M Minhajuddin, N Khan, DA Pollyea, JR Myers, ...
Haematologica 102 (6), 1054, 2017
232017
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