Computational thermostabilization of an enzyme A Korkegian, ME Black, D Baker, BL Stoddard Science 308 (5723), 857-860, 2005 | 460 | 2005 |
Yeast cytosine deaminase mutants with increased thermostability impart sensitivity to 5-fluorocytosine TS Stolworthy, AM Korkegian, CL Willmon, A Ardiani, J Cundiff, ... Journal of molecular biology 377 (3), 854-869, 2008 | 64 | 2008 |
Identification of Morpholino Thiophenes as Novel Mycobacterium tuberculosis Inhibitors, Targeting QcrB LAT Cleghorn, PC Ray, J Odingo, A Kumar, H Wescott, A Korkegian, ... Journal of Medicinal Chemistry 61 (15), 6592-6608, 2018 | 56 | 2018 |
The synthesis and evaluation of triazolopyrimidines as anti-tubercular agents ES Zuniga, A Korkegian, S Mullen, EJ Hembre, PL Ornstein, G Cortez, ... Bioorganic & Medicinal Chemistry 25 (15), 3922-3946, 2017 | 52 | 2017 |
A Target-Based Whole Cell Screen Approach To Identify Potential Inhibitors of Mycobacterium tuberculosis Signal Peptidase SA Bonnett, J Ollinger, S Chandrasekera, S Florio, T O’Malley, M Files, ... ACS infectious diseases 2 (12), 893-902, 2016 | 37 | 2016 |
Discovery of a cofactor-independent inhibitor of Mycobacterium tuberculosis InhA Y Xia, Y Zhou, DS Carter, MB McNeil, W Choi, J Halladay, PW Berry, ... Life Science Alliance 1 (3), 2018 | 34 | 2018 |
The 7-phenyl benzoxaborole series is active against Mycobacterium tuberculosis A Korkegian, T O'Malley, Y Xia, Y Zhou, DS Carter, B Sunde, L Flint, ... Tuberculosis 108, 96-98, 2018 | 29 | 2018 |
Mutations in the essential arabinosyltransferase EmbC lead to alterations in Mycobacterium tuberculosis lipoarabinomannan A Korkegian, DM Roberts, R Blair, T Parish Journal of Biological Chemistry 289 (51), 35172-35181, 2014 | 23 | 2014 |
Spirocycle MmpL3 Inhibitors with Improved hERG and Cytotoxicity Profiles as Inhibitors of Mycobacterium tuberculosis Growth PC Ray, M Huggett, PA Turner, M Taylor, LAT Cleghorn, J Early, A Kumar, ... ACS omega 6 (3), 2284-2311, 2021 | 19 | 2021 |
8‐Hydroxyquinolines are bactericidal against Mycobacterium tuberculosis JO Odingo, JV Early, J Smith, J Johnson, MA Bailey, M Files, J Guzman, ... Drug Development Research 80 (5), 566-572, 2019 | 19 | 2019 |
Synthesis and biological evaluation of aryl-oxadiazoles as inhibitors of Mycobacterium tuberculosis MA Martinez-Grau, ICG Valcarcel, JV Early, RK Gessner, CS de Melo, ... Bioorganic & Medicinal Chemistry Letters 28 (10), 1758-1764, 2018 | 13 | 2018 |
A Novel 6-Benzyl Ether Benzoxaborole Is Active against Mycobacterium tuberculosisIn Vitro N Patel, T O'Malley, YK Zhang, Y Xia, B Sunde, L Flint, A Korkegian, ... Antimicrobial Agents and Chemotherapy 61 (9), 10.1128/aac. 01205-17, 2017 | 13 | 2017 |
Efficacy and improved resistance potential of a cofactor-independent InhA inhibitor of Mycobacterium tuberculosis in the C3HeB/FeJ mouse model GT Robertson, VA Ektnitphong, MS Scherman, MB McNeil, D Dennison, ... Antimicrobial Agents and Chemotherapy 63 (4), 10.1128/aac. 02071-18, 2019 | 12 | 2019 |
Construction of an overexpression library for Mycobacterium tuberculosis E Melief, R Kokoczka, M Files, MA Bailey, T Alling, H Li, J Ahn, A Misquith, ... Biology Methods and Protocols 3 (1), bpy009, 2018 | 12 | 2018 |
InhA inhibitors have activity against non-replicating Mycobacterium tuberculosis L Flint, A Korkegian, T Parish PLoS One 15 (11), e0239354, 2020 | 11 | 2020 |
Mechanisms of resistance against NITD-916, a direct inhibitor of Mycobacterium tuberculosis InhA MB McNeil, D Dennison, C Shelton, L Flint, A Korkegian, T Parish Tuberculosis 107, 133-136, 2017 | 10 | 2017 |
Design, synthesis and SAR of antitubercular benzylpiperazine ureas S Satish, R Chitral, A Kori, B Sharma, J Puttur, AA Khan, D Desle, ... Molecular Diversity, 1-24, 2021 | 6 | 2021 |
Novel chemical entities inhibiting Mycobacterium tuberculosis growth identified by phenotypic high-throughput screening A Kumar, S Chettiar, BS Brown, J Early, J Ollinger, M Files, MA Bailey, ... Scientific Reports 12 (1), 14879, 2022 | 4 | 2022 |
Triazolopyrimidines target aerobic respiration in Mycobacterium tuberculosis C Shelton, M McNeil, R Allen, L Flint, D Russell, B Berube, A Korkegian, ... Antimicrobial Agents and Chemotherapy 66 (4), e02041-21, 2022 | 4 | 2022 |
Identification of 2-amino benzothiazoles with bactericidal activity against Mycobacterium tuberculosis S Bonnett, JA Jee, S Chettiar, Y Ovechkina, A Korkegian, E Greve, ... Microbiology Spectrum 11 (1), e04974-22, 2023 | 1 | 2023 |