| RNA catalyses nuclear pre-mRNA splicing SM Fica, N Tuttle, T Novak, NS Li, J Lu, P Koodathingal, Q Dai, JP Staley, ... Nature 503 (7475), 229-234, 2013 | 437 | 2013 |
| Cryo-EM structure of the spliceosome immediately after branching WP Galej, ME Wilkinson, SM Fica, C Oubridge, AJ Newman, K Nagai Nature 537 (7619), 197-201, 2016 | 257 | 2016 |
| Cryo-electron microscopy snapshots of the spliceosome: structural insights into a dynamic ribonucleoprotein machine SM Fica, K Nagai Nature structural & molecular biology 24 (10), 791-799, 2017 | 210 | 2017 |
| Structure of a spliceosome remodelled for exon ligation SM Fica, C Oubridge, WP Galej, ME Wilkinson, XC Bai, AJ Newman, ... Nature 542 (7641), 377-380, 2017 | 186 | 2017 |
| Evidence for a group II intron–like catalytic triplex in the spliceosome SM Fica, MA Mefford, JA Piccirilli, JP Staley Nature structural & molecular biology 21 (5), 464-471, 2014 | 120 | 2014 |
| A human postcatalytic spliceosome structure reveals essential roles of metazoan factors for exon ligation SM Fica, C Oubridge, ME Wilkinson, AJ Newman, K Nagai Science 363 (6428), 710-714, 2019 | 117 | 2019 |
| Postcatalytic spliceosome structure reveals mechanism of 3′–splice site selection ME Wilkinson, SM Fica, WP Galej, CM Norman, AJ Newman, K Nagai Science 358 (6368), 1283-1288, 2017 | 115 | 2017 |
| CryoEM structures of two spliceosomal complexes: starter and dessert at the spliceosome feast THD Nguyen, WP Galej, SM Fica, PC Lin, AJ Newman, K Nagai Current opinion in structural biology 36, 48-57, 2016 | 66 | 2016 |
| A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation MJ Schellenberg, T Wu, DB Ritchie, S Fica, JP Staley, KA Atta, P LaPointe, ... Nature structural & molecular biology 20 (6), 728-734, 2013 | 52 | 2013 |
| Structural basis for conformational equilibrium of the catalytic spliceosome ME Wilkinson, SM Fica, WP Galej, K Nagai Molecular Cell 81 (7), 1439-1452. e9, 2021 | 46 | 2021 |
| m6A modification of U6 snRNA modulates usage of two major classes of pre-mRNA 5’splice site MT Parker, BK Soanes, J Kusakina, A Larrieu, K Knop, N Joy, ... Elife 11, e78808, 2022 | 40 | 2022 |
| Cryo-EM snapshots of the human spliceosome reveal structural adaptions for splicing regulation SM Fica Current opinion in structural biology 65, 139-148, 2020 | 30 | 2020 |
| De novo variants in the RNU4-2 snRNA cause a frequent neurodevelopmental syndrome Y Chen, R Dawes, HC Kim, A Ljungdahl, SL Stenton, S Walker, J Lord, ... Nature 632 (8026), 832-840, 2024 | 24 | 2024 |
| psiCLIP reveals dynamic RNA binding by DEAH-box helicases before and after exon ligation LM Strittmatter, C Capitanchik, AJ Newman, M Hallegger, CM Norman, ... Nature Communications 12 (1), 1488, 2021 | 17 | 2021 |
| De novo variants in the non-coding spliceosomal snRNA gene RNU4-2 are a frequent cause of syndromic neurodevelopmental disorders Y Chen, R Dawes, HC Kim, SL Stenton, S Walker, A Ljungdahl, J Lord, ... medRxiv, 2024 | 14 | 2024 |
| Monovalent metal ion binding promotes the first transesterification reaction in the spliceosome J Aupič, J Borišek, SM Fica, WP Galej, A Magistrato Nature Communications 14 (1), 8482, 2023 | 9 | 2023 |
| Inter-species association mapping links splice site evolution to METTL16 and SNRNP27K MT Parker, SM Fica, GJ Barton, GG Simpson Elife 12, e91997, 2023 | 8 | 2023 |
| Mechanistic Insights into Mammalian Pre‐mRNA Splicing SM Fica, EC Small, M Mefford, JP Staley Posttranscriptional Gene Regulation: RNA Processing in Eukaryotes, 133-161, 2013 | 2 | 2013 |
| The evolution of splice site sequence preference is linked to the U6 snRNA m6A methyltransferase METTL16 MT Parker, SM Fica, GJ Barton, GG Simpson bioRxiv, 2023.05. 04.539401, 2023 | 1 | 2023 |
| RNA splicing: a split consensus reveals two major 5′ splice site classes MT Parker, SM Fica, GG Simpson Open Biology 15 (1), 240293, 2025 | | 2025 |
Wojciech GalejEuropean Molecular Biology LaboratoryVerified email at embl.fr
