Gremlin 1 identifies a skeletal stem cell with bone, cartilage, and reticular stromal potential DL Worthley, M Churchill, JT Compton, Y Tailor, M Rao, Y Si, D Levin, ... Cell 160 (1), 269-284, 2015 | 633 | 2015 |
Nerve growth factor promotes gastric tumorigenesis through aberrant cholinergic signaling Y Hayakawa, K Sakitani, M Konishi, S Asfaha, R Niikura, H Tomita, ... Cancer cell 31 (1), 21-34, 2017 | 409 | 2017 |
β2 adrenergic-neurotrophin feedforward loop promotes pancreatic cancer BW Renz, R Takahashi, T Tanaka, M Macchini, Y Hayakawa, Z Dantes, ... Cancer cell 33 (1), 75-90. e7, 2018 | 379 | 2018 |
Mist1 expressing gastric stem cells maintain the normal and neoplastic gastric epithelium and are supported by a perivascular stem cell niche Y Hayakawa, H Ariyama, J Stancikova, K Sakitani, S Asfaha, BW Renz, ... Cancer cell 28 (6), 800-814, 2015 | 289 | 2015 |
Macrophage-derived extracellular vesicle-packaged WNTs rescue intestinal stem cells and enhance survival after radiation injury S Saha, E Aranda, Y Hayakawa, P Bhanja, S Atay, NP Brodin, J Li, ... Nature communications 7 (1), 13096, 2016 | 251 | 2016 |
Dclk1 defines quiescent pancreatic progenitors that promote injury-induced regeneration and tumorigenesis CB Westphalen, Y Takemoto, T Tanaka, M Macchini, Z Jiang, BW Renz, ... Cell stem cell 18 (4), 441-455, 2016 | 221 | 2016 |
Cholinergic signaling via muscarinic receptors directly and indirectly suppresses pancreatic tumorigenesis and cancer stemness BW Renz, T Tanaka, M Sunagawa, R Takahashi, Z Jiang, M Macchini, ... Cancer discovery 8 (11), 1458-1473, 2018 | 200 | 2018 |
CCK2R identifies and regulates gastric antral stem cell states and carcinogenesis Y Hayakawa, G Jin, H Wang, X Chen, CB Westphalen, S Asfaha, ... Gut 64 (4), 544-553, 2015 | 113 | 2015 |
Neural innervation stimulates splenic TFF2 to arrest myeloid cell expansion and cancer Z Dubeykovskaya, Y Si, X Chen, DL Worthley, BW Renz, AM Urbanska, ... Nature communications 7 (1), 10517, 2016 | 102 | 2016 |
Bone marrow myeloid cells regulate myeloid-biased hematopoietic stem cells via a histamine-dependent feedback loop X Chen, H Deng, MJ Churchill, LL Luchsinger, X Du, TH Chu, ... Cell stem cell 21 (6), 747-760. e7, 2017 | 85 | 2017 |
Obesity accelerates Helicobacter felis-induced gastric carcinogenesis by enhancing immature myeloid cell trafficking and TH17 response RE Ericksen, S Rose, CB Westphalen, W Shibata, S Muthupalani, Y Tailor, ... Gut 63 (3), 385-394, 2014 | 78 | 2014 |
Detection of premalignant gastrointestinal lesions using surface-enhanced resonance Raman scattering–nanoparticle endoscopy S Harmsen, S Rogalla, R Huang, M Spaliviero, V Neuschmelting, ... Acs Nano 13 (2), 1354-1364, 2019 | 70 | 2019 |
Interleukin-1β-induced pancreatitis promotes pancreatic ductal adenocarcinoma via B lymphocyte–mediated immune suppression R Takahashi, M Macchini, M Sunagawa, Z Jiang, T Tanaka, G Valenti, ... Gut 70 (2), 330-341, 2021 | 69 | 2021 |
Progastrin stimulates colonic cell proliferation via CCK2R-and β-arrestin–dependent suppression of BMP2 G Jin, CB Westphalen, Y Hayakawa, DL Worthley, S Asfaha, X Yang, ... Gastroenterology 145 (4), 820-830. e10, 2013 | 55 | 2013 |
Prox1-positive cells monitor and sustain the murine intestinal epithelial cholinergic niche M Middelhoff, H Nienhüser, G Valenti, HC Maurer, Y Hayakawa, ... Nature communications 11 (1), 111, 2020 | 44 | 2020 |
The G-protein coupled receptor 56, expressed in colonic stem and cancer cells, binds progastrin to promote proliferation and carcinogenesis G Jin, K Sakitani, H Wang, Y Jin, A Dubeykovskiy, DL Worthley, Y Tailor, ... Oncotarget 8 (25), 40606, 2017 | 43 | 2017 |
Histidine decarboxylase (HDC)-expressing granulocytic myeloid cells induce and recruit Foxp3+ regulatory T cells in murine colon cancer X Chen, Y Takemoto, H Deng, M Middelhoff, RA Friedman, TH Chu, ... Oncoimmunology 6 (3), e1290034, 2017 | 40 | 2017 |
BHLHA15-positive secretory precursor cells can give rise to tumors in intestine and colon in mice Y Hayakawa, M Tsuboi, S Asfaha, H Kinoshita, R Niikura, M Konishi, ... Gastroenterology 156 (4), 1066-1081. e16, 2019 | 39 | 2019 |
IL-17 producing mast cells promote the expansion of myeloid-derived suppressor cells in a mouse allergy model of colorectal cancer X Chen, MJ Churchill, KK Nagar, YH Tailor, T Chu, BS Rush, Z Jiang, ... Oncotarget 6 (32), 32966, 2015 | 39 | 2015 |
CXCR4-expressing Mist1+ progenitors in the gastric antrum contribute to gastric cancer development K Sakitani, Y Hayakawa, H Deng, H Ariyama, H Kinoshita, M Konishi, ... Oncotarget 8 (67), 111012, 2017 | 33 | 2017 |