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Simon Mitchell
Simon Mitchell
Reader in Cancer Research, Brighton and Sussex Medical School, University of Sussex
Verified email at bsms.ac.uk - Homepage
Title
Cited by
Cited by
Year
Signaling via the NFκB system
S Mitchell, J Vargas, A Hoffmann
Wiley Interdisciplinary Reviews: Systems Biology and Medicine 8 (3), 227-241, 2016
10852016
Identification of neural oscillations and epileptiform changes in human brain organoids
RA Samarasinghe, OA Miranda, JE Buth, S Mitchell, I Ferando, ...
Nature neuroscience 24 (10), 1488-1500, 2021
1892021
A regulatory circuit controlling the dynamics of NFκB cRel transitions B cells from proliferation to plasma cell differentiation
K Roy, S Mitchell, Y Liu, S Ohta, Y Lin, MO Metzig, SL Nutt, A Hoffmann
Immunity 50 (3), 616-628. e6, 2019
792019
Nongenetic origins of cell-to-cell variability in B lymphocyte proliferation
S Mitchell, K Roy, TA Zangle, A Hoffmann
Proceedings of the National Academy of Sciences 115 (12), E2888-E2897, 2018
722018
Dissecting the regulatory strategies of NF-κB RelA target genes in the inflammatory response reveals differential transactivation logics
KA Ngo, K Kishimoto, J Davis-Turak, A Pimplaskar, Z Cheng, R Spreafico, ...
Cell reports 30 (8), 2758-2775. e6, 2020
612020
An NFκB activity calculator to delineate signaling crosstalk: type I and II interferons enhance NFκB via distinct mechanisms
S Mitchell, EL Mercado, A Adelaja, JQ Ho, QJ Cheng, G Ghosh, ...
Frontiers in immunology 10, 1425, 2019
462019
A computational model of liver iron metabolism
S Mitchell, P Mendes
PLoS computational biology 9 (11), e1003299, 2013
432013
Polypyrimidine tract-binding protein blocks miRNA-124 biogenesis to enforce its neuronal-specific expression in the mouse
KH Yeom, S Mitchell, AJ Linares, S Zheng, CH Lin, XJ Wang, A Hoffmann, ...
Proceedings of the National Academy of Sciences 115 (47), E11061-E11070, 2018
352018
Identifying noise sources governing cell-to-cell variability
S Mitchell, A Hoffmann
Current opinion in systems biology 8, 39-45, 2018
302018
Neuronal network topology indicates distinct recovery processes after stroke
S Latifi, S Mitchell, R Habibey, F Hosseini, E Donzis, AM Estrada-Sánchez, ...
Cerebral Cortex 30 (12), 6363-6375, 2020
292020
TLR9 expression in chronic lymphocytic leukemia identifies a promigratory subpopulation and novel therapeutic target
E Kennedy, E Coulter, E Halliwell, N Profitos-Peleja, E Walsby, B Clark, ...
Blood, The Journal of the American Society of Hematology 137 (22), 3064-3078, 2021
282021
Identifying determinants of persistent MRSA bacteremia using mathematical modeling
T Mikkaichi, MR Yeaman, A Hoffmann, ...
PLoS computational biology 15 (7), e1007087, 2019
212019
NF-kB and the CLL microenvironment
A O’Donnell, C Pepper, S Mitchell, A Pepper
Frontiers in Oncology 13, 1169397, 2023
202023
The NF-κB multidimer system model: A knowledge base to explore diverse biological contexts
S Mitchell, R Tsui, ZC Tan, A Pack, A Hoffmann
Science signaling 16 (776), eabo2838, 2023
202023
Human DNA methylation signatures differentiate persistent from resolving MRSA bacteremia
YL Chang, M Rossetti, DW Gjertson, L Rubbi, M Thompson, DJ Montoya, ...
Proceedings of the National Academy of Sciences 118 (10), e2000663118, 2021
202021
An incoherent feedforward loop interprets NFκB/RelA dynamics to determine TNF‐induced necroptosis decisions
M Oliver Metzig, Y Tang, S Mitchell, B Taylor, R Foreman, R Wollman, ...
Molecular systems biology 16 (12), e9677, 2020
202020
Training the 21st century immunologist
R Spreafico, S Mitchell, A Hoffmann
Trends in immunology 36 (5), 283-285, 2015
172015
Machine learning for determining accurate outcomes in criminal trials
J Mitchell, S Mitchell, C Mitchell
Law, Probability and Risk 19 (1), 43-65, 2020
162020
Targeting the non-canonical NF-κB pathway in chronic lymphocytic leukemia and multiple myeloma
TA Burley, E Kennedy, G Broad, M Boyd, D Li, T Woo, C West, EE Ladikou, ...
Cancers 14 (6), 1489, 2022
102022
What will B will B: identifying molecular determinants of diverse B-cell fate decisions through systems biology
S Mitchell
Frontiers in Cell and Developmental Biology 8, 616592, 2021
102021
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