Possu Huang
Possu Huang
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Cited by
Cited by
The coming of age of de novo protein design
PS Huang, SE Boyken, D Baker
Nature 537 (7620), 320-327, 2016
A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield
R Pejchal, KJ Doores, LM Walker, R Khayat, PS Huang, SK Wang, ...
Science 334 (6059), 1097-1103, 2011
Rational HIV immunogen design to target specific germline B cell receptors
J Jardine, JP Julien, S Menis, T Ota, O Kalyuzhniy, A McGuire, D Sok, ...
Science 340 (6133), 711-716, 2013
Macromolecular modeling and design in Rosetta: recent methods and frameworks
JK Leman, BD Weitzner, SM Lewis, J Adolf-Bryfogle, N Alam, RF Alford, ...
Nature methods 17 (7), 665-680, 2020
Protein structure determination using metagenome sequence data
S Ovchinnikov, H Park, N Varghese, PS Huang, GA Pavlopoulos, DE Kim, ...
Science 355 (6322), 294-298, 2017
Design of a hyperstable 60-subunit protein icosahedron
Y Hsia, JB Bale, S Gonen, D Shi, W Sheffler, KK Fong, U Nattermann, ...
Nature 535 (7610), 136-139, 2016
Accurate de novo design of hyperstable constrained peptides
G Bhardwaj, VK Mulligan, CD Bahl, JM Gilmore, PJ Harvey, O Cheneval, ...
Nature 538 (7625), 329-335, 2016
RosettaRemodel: a generalized framework for flexible backbone protein design
PS Huang, YEA Ban, F Richter, I Andre, R Vernon, WR Schief, D Baker
PloS one 6 (8), e24109, 2011
De novo design of a fluorescence-activating β-barrel
J Dou, AA Vorobieva, W Sheffler, LA Doyle, H Park, MJ Bick, B Mao, ...
Nature 561 (7724), 485-491, 2018
High thermodynamic stability of parametrically designed helical bundles
PS Huang, G Oberdorfer, C Xu, XY Pei, BL Nannenga, JM Rogers, ...
science 346 (6208), 481-485, 2014
Exploring the repeat protein universe through computational protein design
TJ Brunette, F Parmeggiani, PS Huang, G Bhabha, DC Ekiert, ...
Nature 528 (7583), 580-584, 2015
De novo design of a four-fold symmetric TIM-barrel protein with atomic-level accuracy
PS Huang, K Feldmeier, F Parmeggiani, DA Fernandez Velasco, ...
Nature chemical biology 12 (1), 29-34, 2016
Progen: Language modeling for protein generation
A Madani, B McCann, N Naik, NS Keskar, N Anand, RR Eguchi, ...
arXiv preprint arXiv:2004.03497, 2020
Computation-guided backbone grafting of a discontinuous motif onto a protein scaffold
ML Azoitei, BE Correia, YEA Ban, C Carrico, O Kalyuzhniy, L Chen, ...
Science 334 (6054), 373-376, 2011
Generative modeling for protein structures
N Anand, P Huang
Advances in neural information processing systems 31, 2018
Protein sequence design with a learned potential
N Anand, R Eguchi, II Mathews, CP Perez, A Derry, RB Altman, PS Huang
Nature communications 13 (1), 746, 2022
Computational design of transmembrane pores
C Xu, P Lu, TM Gamal El-Din, XY Pei, MC Johnson, A Uyeda, MJ Bick, ...
Nature 585 (7823), 129-134, 2020
A de novo designed protein–protein interface
PS Huang, JJ Love, SL Mayo
Protein Science 16 (12), 2770-2774, 2007
Theoretical basis for stabilizing messenger RNA through secondary structure design
HK Wayment-Steele, DS Kim, CA Choe, JJ Nicol, R Wellington-Oguri, ...
Nucleic acids research 49 (18), 10604-10617, 2021
Control of repeat-protein curvature by computational protein design
K Park, BW Shen, F Parmeggiani, PS Huang, BL Stoddard, D Baker
Nature structural & molecular biology 22 (2), 167-174, 2015
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