Curaxins: anticancer compounds that simultaneously suppress NF-κB and activate p53 by targeting FACT AV Gasparian, CA Burkhart, AA Purmal, L Brodsky, M Pal, M Saranadasa, ... Science translational medicine 3 (95), 95ra74-95ra74, 2011 | 154 | 2011 |
FACT is a sensor of DNA torsional stress in eukaryotic cells A Safina, P Cheney, M Pal, L Brodsky, A Ivanov, K Kirsanov, E Lesovaya, ... Nucleic acids research 45 (4), 1925-1945, 2017 | 63 | 2017 |
Blood BDNF level is gender specific in severe depression A Kreinin, S Lisson, E Nesher, J Schneider, J Bergman, K Farhat, J Farah, ... PLoS One 10 (5), e0127643, 2015 | 58 | 2015 |
Targeting FACT complex suppresses mammary tumorigenesis in Her2/neu transgenic mice IE Koman, M Commane, G Paszkiewicz, B Hoonjan, S Pal, A Safina, ... Cancer prevention research 5 (8), 1025-1035, 2012 | 55 | 2012 |
Apoptosis inhibitor as a suppressor of tumor progression: expression of Bcl-2 eliminates selective advantages for p53-deficient cells in the tumor KV Gurova, SSS Kwek, IE Koman, AP Komarov, E Kandel, MA Nikiforov, ... Cancer biology & therapy 1 (1), 39-44, 2002 | 39 | 2002 |
Role of chromatin damage and chromatin trapping of FACT in mediating the anticancer cytotoxicity of DNA-binding small-molecule drugs E Nesher, A Safina, I Aljahdali, S Portwood, ES Wang, I Koman, J Wang, ... Cancer research 78 (6), 1431-1443, 2018 | 29 | 2018 |
Method for noninvasive analysis of proteins and small molecules from ancient objects M Manfredi, E Barberis, F Gosetti, E Conte, G Gatti, C Mattu, E Robotti, ... Analytical chemistry 89 (6), 3310-3317, 2017 | 28 | 2017 |
TRAIN (Transcription of Repeats Activates INterferon) in response to chromatin destabilization induced by small molecules in mammalian cells K Leonova, A Safina, E Nesher, P Sandlesh, R Pratt, C Burkhart, ... Elife 7, e30842, 2018 | 21 | 2018 |
Synapsin IIb as a functional marker of submissive behavior E Nesher, I Koman, M Gross, T Tikhonov, M Bairachnaya, ... Scientific reports 5 (1), 1-12, 2015 | 15 | 2015 |
Cepharanthine: a review of the antiviral potential of a Japanese-approved alopecia drug in COVID-19 M Rogosnitzky, P Okediji, I Koman Pharmacological Reports, 1-8, 2020 | 12 | 2020 |
Seasonality and BDNF polymorphism influences depression outcome in patients with atopic dermatitis and psoriasis T Vinnik, M Kirby, M Bairachnaya, I Koman, T Tarkina, G Sadykova, ... The World Journal of Biological Psychiatry 18 (8), 604-614, 2017 | 9 | 2017 |
Novel synthetic cyclic integrin αvβ3 binding peptide ALOS4: Antitumor activity in mouse melanoma models S Yacobovich, L Tuchinsky, M Kirby, T Kardash, O Agranyoni, E Nesher, ... Oncotarget 7 (39), 63549, 2016 | 8 | 2016 |
Link between personality and response to THC exposure T Kardash, D Rodin, M Kirby, N Davis, I Koman, J Gorelick, I Michaelevski, ... Behavioural brain research 379, 112361, 2020 | 2 | 2020 |
Treatment of inflammation A Gudkov, E Nesher, A Pinhasov, I Koman, Y Leonova US Patent App. 17/068,849, 2021 | | 2021 |
Immune checkpoint protein VSIG4 as a biomarker of aging in murine adipose tissue BM Hall, AS Gleiberman, E Strom, PA Krasnov, D Frescas, S Vujcic, ... Aging cell 19 (10), e13219, 2020 | | 2020 |
Cytotoxicity of Exogenous Acetoacetate in Lithium Salt Form Is Mediated by Lithium and Not Acetoacetate R Cohen-Harazi, S Hofmann, V Kogan, H Fulman-Levy, K Abaev, ... Anticancer Research 40 (7), 3831-3837, 2020 | | 2020 |
Patient-derived Tumor Spheroid Cultures as a Promising Tool to Assist Personalized Therapeutic Decisions S Hofmann, R Cohen-Harazi, Y Maizels, I Koman | | 2020 |
Chromatin trapping is a key factor for anticancer cytotoxicity of DNA-binding small molecule drugs E Nesher, A Safina, I Aljahdali, S Portwood, E Wang, J Wang, I Koman, ... Cancer Research 79 (13 Supplement), 1755-1755, 2019 | | 2019 |
Personality may influence behavioral response to cannabis T Kardash, D Rodin, M Kirby, I Koman, I Michaelevski, A Pinhasov BioRxiv, 674044, 2019 | | 2019 |
Anticancer effect of a new cyclic peptide ALOS4 is associated with its systemic anti-inflammatory activity E Nesher, A Pinhasov, M Becker, M Kirby, RC Harazi, S Yakobovich, ... Cancer Research 78 (13 Supplement), 2866-2866, 2018 | | 2018 |