עקוב אחר
Pablo Sardi
Pablo Sardi
שותפות לא ידועה
כתובת אימייל מאומתת בדומיין genzyme.com
כותרת
צוטט על ידי
צוטט על ידי
שנה
Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson’s disease
LF Burbulla, P Song, JR Mazzulli, E Zampese, YC Wong, S Jeon, ...
Science 357 (6357), 1255-1261, 2017
7302017
Antisense oligonucleotides delivered to the mouse CNS ameliorate symptoms of severe spinal muscular atrophy
MA Passini, J Bu, AM Richards, C Kinnecom, SP Sardi, LM Stanek, Y Hua, ...
Science translational medicine 3 (72), 72ra18-72ra18, 2011
5652011
iPSC-derived neurons from GBA1-associated Parkinson’s disease patients show autophagic defects and impaired calcium homeostasis
DC Schöndorf, M Aureli, FE McAllister, CJ Hindley, F Mayer, B Schmid, ...
Nature communications 5 (1), 4028, 2014
5362014
Presenilin-dependent ErbB4 nuclear signaling regulates the timing of astrogenesis in the developing brain
SP Sardi, J Murtie, S Koirala, BA Patten, G Corfas
Cell 127 (1), 185-197, 2006
3892006
The Parkinson's progression markers initiative (PPMI)–establishing a PD biomarker cohort
K Marek, S Chowdhury, A Siderowf, S Lasch, CS Coffey, ...
Annals of clinical and translational neurology 5 (12), 1460-1477, 2018
3822018
ER stress and autophagic perturbations lead to elevated extracellular α-synuclein in GBA-N370S Parkinson's iPSC-derived dopamine neurons
HJR Fernandes, EM Hartfield, HC Christian, E Emmanoulidou, Y Zheng, ...
Stem cell reports 6 (3), 342-356, 2016
3552016
Acid β‐glucosidase mutants linked to Gaucher disease, Parkinson disease, and Lewy body dementia alter α‐synuclein processing
V Cullen, SP Sardi, J Ng, YH Xu, Y Sun, JJ Tomlinson, P Kolodziej, I Kahn, ...
Annals of neurology 69 (6), 940-953, 2011
3552011
CNS-targeted gene therapy improves survival and motor function in a mouse model of spinal muscular atrophy
MA Passini, J Bu, EM Roskelley, AM Richards, SP Sardi, CR O’Riordan, ...
The Journal of clinical investigation 120 (4), 1253-1264, 2010
3462010
Loss of erbB signaling in oligodendrocytes alters myelin and dopaminergic function, a potential mechanism for neuropsychiatric disorders
K Roy, JC Murtie, BF El-Khodor, N Edgar, SP Sardi, BM Hooks, ...
Proceedings of the National Academy of Sciences 104 (19), 8131-8136, 2007
3402007
CNS expression of glucocerebrosidase corrects α-synuclein pathology and memory in a mouse model of Gaucher-related synucleinopathy
SP Sardi, J Clarke, C Kinnecom, TJ Tamsett, L Li, LM Stanek, MA Passini, ...
Proceedings of the National Academy of Sciences 108 (29), 12101-12106, 2011
3392011
Augmenting CNS glucocerebrosidase activity as a therapeutic strategy for parkinsonism and other Gaucher-related synucleinopathies
SP Sardi, J Clarke, C Viel, M Chan, TJ Tamsett, CM Treleaven, J Bu, ...
Proceedings of the National Academy of Sciences 110 (9), 3537-3542, 2013
2852013
iPSC-derived dopamine neurons reveal differences between monozygotic twins discordant for Parkinson’s disease
CM Woodard, BA Campos, SH Kuo, MJ Nirenberg, MW Nestor, M Zimmer, ...
Cell reports 9 (4), 1173-1182, 2014
2572014
Revisiting protein aggregation as pathogenic in sporadic Parkinson and Alzheimer diseases
AJ Espay, JA Vizcarra, L Marsili, AE Lang, DK Simon, A Merola, ...
Neurology 92 (7), 329-337, 2019
2122019
Glucocerebrosidase depletion enhances cell-to-cell transmission of α-synuclein
EJ Bae, NY Yang, M Song, CS Lee, JS Lee, BC Jung, HJ Lee, S Kim, ...
Nature communications 5 (1), 4755, 2014
2002014
Mitochondrial dysfunction and mitophagy defect triggered by heterozygous GBA mutations
H Li, A Ham, TC Ma, SH Kuo, E Kanter, D Kim, HS Ko, Y Quan, SP Sardi, ...
Autophagy 15 (1), 113-130, 2019
1942019
Glucosylceramide synthase inhibition alleviates aberrations in synucleinopathy models
SP Sardi, C Viel, J Clarke, CM Treleaven, AM Richards, H Park, ...
Proceedings of the National Academy of Sciences 114 (10), 2699-2704, 2017
1852017
Silencing mutant huntingtin by adeno-associated virus-mediated RNA interference ameliorates disease manifestations in the YAC128 mouse model of Huntington's disease
LM Stanek, SP Sardi, B Mastis, AR Richards, CM Treleaven, T Taksir, ...
Human gene therapy 25 (5), 461-474, 2014
1832014
Targeted therapies for Parkinson's disease: from genetics to the clinic
SP Sardi, JM Cedarbaum, P Brundin
Movement Disorders 33 (5), 684-696, 2018
1692018
Longitudinal change of clinical and biological measures in early Parkinson's disease: Parkinson's progression markers initiative cohort
T Simuni, A Siderowf, S Lasch, CS Coffey, C Caspell‐Garcia, D Jennings, ...
Movement Disorders 33 (5), 771-782, 2018
1532018
SMN regulates axonal local translation via miR-183/mTOR pathway
MJ Kye, ED Niederst, MH Wertz, ICG Gonçalves, B Akten, KZ Dover, ...
Human molecular genetics 23 (23), 6318-6331, 2014
1462014
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