| A new protein containing an SH2 domain that inhibits JAK kinases TA Endo, M Masuhara, M Yokouchi, R Suzuki, H Sakamoto, K Mitsui, ... Nature 387 (6636), 921-924, 1997 | 1937 | 1997 |
| SOCS proteins, cytokine signalling and immune regulation A Yoshimura, T Naka, M Kubo Nature Reviews Immunology 7 (6), 454-465, 2007 | 1902 | 2007 |
| Interleukin 27 negatively regulates the development of interleukin 17–producing T helper cells during chronic inflammation of the central nervous system JS Stumhofer, A Laurence, EH Wilson, E Huang, CM Tato, LM Johnson, ... Nature immunology 7 (9), 937-945, 2006 | 1196 | 2006 |
| Conditional ablation of Stat3 or Socs3 discloses a dual role for reactive astrocytes after spinal cord injury S Okada, M Nakamura, H Katoh, T Miyao, T Shimazaki, K Ishii, J Yamane, ... Nature medicine 12 (7), 829-834, 2006 | 1089 | 2006 |
| Function of miR-146a in controlling Treg cell-mediated regulation of Th1 responses LF Lu, MP Boldin, A Chaudhry, LL Lin, KD Taganov, T Hanada, ... Cell 142 (6), 914-929, 2010 | 1069 | 2010 |
| Foxp3-dependent microRNA155 confers competitive fitness to regulatory T cells by targeting SOCS1 protein LF Lu, TH Thai, DP Calado, A Chaudhry, M Kubo, K Tanaka, GB Loeb, ... Immunity 30 (1), 80-91, 2009 | 1029 | 2009 |
| A novel cytokine‐inducible gene CIS encodes an SH2‐containing protein that binds to tyrosine‐phosphorylated interleukin 3 and erythropoietin receptors. A Yoshimura, T Ohkubo, T Kiguchi, NA Jenkins, DJ Gilbert, NG Copeland, ... The EMBO journal 14 (12), 2816-2826, 1995 | 999 | 1995 |
| Regulation of cytokine signaling and inflammation T Hanada, A Yoshimura Cytokine & growth factor reviews 13 (4-5), 413-421, 2002 | 982 | 2002 |
| The JAK‐binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop H Yasukawa, H Misawa, H Sakamoto, M Masuhara, A Sasaki, T Wakioka, ... The EMBO journal, 1999 | 975 | 1999 |
| Pivotal role of cerebral interleukin-17–producing γδT cells in the delayed phase of ischemic brain injury T Shichita, Y Sugiyama, H Ooboshi, H Sugimori, R Nakagawa, I Takada, ... Nature medicine 15 (8), 946-950, 2009 | 951 | 2009 |
| IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages H Yasukawa, M Ohishi, H Mori, M Murakami, T Chinen, D Aki, T Hanada, ... Nature immunology 4 (6), 551-556, 2003 | 937 | 2003 |
| Stat3/Socs3 activation by IL-6 transsignaling promotes progression of pancreatic intraepithelial neoplasia and development of pancreatic cancer M Lesina, MU Kurkowski, K Ludes, S Rose-John, M Treiber, G Klöppel, ... Cancer cell 19 (4), 456-469, 2011 | 911 | 2011 |
| Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells Z Chen, A Laurence, Y Kanno, M Pacher-Zavisin, BM Zhu, C Tato, ... Proceedings of the national academy of sciences 103 (21), 8137-8142, 2006 | 838 | 2006 |
| SOCS1/JAB is a negative regulator of LPS-induced macrophage activation I Kinjyo, T Hanada, K Inagaki-Ohara, H Mori, D Aki, M Ohishi, H Yoshida, ... Immunity 17 (5), 583-591, 2002 | 820 | 2002 |
| Suppressors of cytokine signaling and immunity M Kubo, T Hanada, A Yoshimura Nature immunology 4 (12), 1169-1176, 2003 | 793 | 2003 |
| Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity H Mori, R Hanada, T Hanada, D Aki, R Mashima, H Nishinakamura, ... Nature medicine 10 (7), 739-743, 2004 | 763 | 2004 |
| Negative regulation of cytokine signaling pathways H Yasukawa, A Sasaki, A Yoshimura Annual review of immunology 18 (1), 143-164, 2000 | 760 | 2000 |
| Cutting edge: role of IL-27/WSX-1 signaling for induction of T-bet through activation of STAT1 during initial Th1 commitment A Takeda, S Hamano, A Yamanaka, T Hanada, T Ishibashi, TW Mak, ... The Journal of Immunology 170 (10), 4886-4890, 2003 | 720 | 2003 |
| Hepatitis C virus down-regulates insulin receptor substrates 1 and 2 through up-regulation of suppressor of cytokine signaling 3 T Kawaguchi, T Yoshida, M Harada, T Hisamoto, Y Nagao, T Ide, ... The American journal of pathology 165 (5), 1499-1508, 2004 | 700 | 2004 |
| CIS, a cytokine inducible SH2 protein, is a target of the JAK-STAT5 pathway and modulates STAT5 activation A Matsumoto, M Masuhara, K Mitsui, M Yokouchi, M Ohtsubo, H Misawa, ... Blood, The Journal of the American Society of Hematology 89 (9), 3148-3154, 1997 | 662 | 1997 |
