Repurposing the clinically efficacious antifungal agent itraconazole as an anticancer chemotherapeutic JR Pace, AM DeBerardinis, V Sail, SK Tacheva-Grigorova, KA Chan, ... Journal of medicinal chemistry 59 (8), 3635-3649, 2016 | 65 | 2016 |
Intestinal lineage commitment of embryonic stem cells L Cao, JD Gibson, S Miyamoto, V Sail, R Verma, DW Rosenberg, ... Differentiation 81 (1), 1-10, 2011 | 62 | 2011 |
Identification of small molecule translesion synthesis inhibitors that target the Rev1-CT/RIR protein− protein interaction V Sail, AA Rizzo, N Chatterjee, RC Dash, Z Ozen, GC Walker, ... ACS chemical biology 12 (7), 1903-1912, 2017 | 56 | 2017 |
Structure–activity relationships for vitamin D3-based aromatic A-ring analogues as Hedgehog pathway inhibitors AM DeBerardinis, DJ Madden, U Banerjee, V Sail, DS Raccuia, ... Journal of Medicinal Chemistry 57 (9), 3724-3736, 2014 | 33 | 2014 |
Notch pathway modulators as anticancer chemotherapeutics V Sail, MK Hadden Annual reports in medicinal chemistry 47, 267-280, 2012 | 19 | 2012 |
Identification of small molecule Hes1 modulators as potential anticancer chemotherapeutics V Sail, MK Hadden Chemical Biology & Drug Design 81 (3), 334-342, 2013 | 10 | 2013 |
Probing seco-steroid inhibition of the hedgehog signaling pathway EN Thompson, V Sail, DS Raccuia, MK Hadden Molecular and Cellular Biochemistry 450, 75-85, 2019 | 2 | 2019 |
AB-2100, a PSMA-inducible CA9-specific CAR T cell product for the treatment of ccRCC provides long-term tumor responses in preclinical mouse model S Mohanty, J Chen, A Gomez, A Boroughs, I Scarfo, L Lim, K Dang, ... Cancer Research 84 (6_Supplement), 38-38, 2024 | | 2024 |
Characterization of AB-1015 logic-gated CAR induction (ON kinetics), receptor turnover (OFF kinetics), and logic gate sensitivity to ALPG/P and MSLN X Tang, M Chew, R Sudhakar, H Yun, D Sakamoto, V Sail, A Fearon, ... Cancer Research 84 (6_Supplement), 6319-6319, 2024 | | 2024 |
Enhancing TCR T cell function in solid tumors through in vivo combinatorial screens and single-cell analysis D Polyak, J Fuhriman, J Susanto, A Merrell, M Simon, C Oh, A Cordazo, ... Cancer Research 84 (6_Supplement), 7042-7042, 2024 | | 2024 |
Pooled CRISPR screening coupled with single-cell sequencing identifies modifiers of CAR T cell state in the context of chronic antigen stimulation S Joshi, G Wozniak, J Gagnon, K Vucci, A Merrell, M Simon, C Oh, ... Cancer Research 84 (6_Supplement), 7034-7034, 2024 | | 2024 |
Development of AB-2100, an autologous integrated circuit T (ICT) cell therapy targeting CA9 intended for the treatment of ccRCC. M Landon, I Scarfo, M Chew, R Sudhakah, M Nguyen, S Mohanty, J Chen, ... Journal of Clinical Oncology 42 (4_suppl), 472-472, 2024 | | 2024 |
301 Preclinical development of AB-2100, a PSMA neovasculature-inducible CA9 CAR resistant to FASL and TGFb mediated suppression for the treatment of ccRCC I Scarfo, L Lim, K Dang, M Chew, R Sudhakah, M Nguyen, S Mohanty, ... Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023 | | 2023 |
A neovasculature-inducible CA9 CAR resistant to FASL and TGFb mediated suppression for the treatment of ccRCC AC Boroughs, I Scarfo, N Attanasio, T Gardner, JB Smith, J McDevitt, ... Cancer Research 83 (7_Supplement), 4088-4088, 2023 | | 2023 |
Identification of small molecule translesion synthesis inhibitors that target Rev1 protein-protein interactions M Hadden, V Sail, E Thompson, A Rizzo, D Korzhnev ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 251, 2016 | | 2016 |