Tapan Das
Tapan Das
Spyre Therapeutics
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Cited by
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Folding of cytochrome c initiated by submillisecond mixing
S Takahashi, SR Yeh, TK Das, CK Chan, DS Gottfried, DL Rousseau
Nature structural biology 4 (1), 44-50, 1997
Potential aggregation prone regions in biotherapeutics: a survey of commercial monoclonal antibodies
X Wang, TK Das, SK Singh, S Kumar
MAbs 1 (3), 254-267, 2009
Simultaneous observation of the O—O and Fe—O2 stretching modes in oxyhemoglobins
TK Das, M Couture, Y Ouellet, M Guertin, DL Rousseau
Proceedings of the National Academy of Sciences 98 (2), 479-484, 2001
Mutations in the putative H-channel in the cytochrome c oxidase from Rhodobacter sphaeroides show that this channel is not important for proton conduction but reveal modulation …
H Lee, TK Das, DL Rousseau, D Mills, S Ferguson-Miller, RB Gennis
Biochemistry 39 (11), 2989-2996, 2000
Predicting solution aggregation rates for therapeutic proteins: Approaches and challenges
CJ Roberts, TK Das, E Sahin
International Journal of Pharmaceutics, 2011
Chlamydomonas chloroplast ferrous hemoglobin: heme pocket structure and reactions with ligands
M Couture, TK Das, HC Lee, J Peisach, DL Rousseau, BA Wittenberg, ...
Journal of Biological Chemistry 274 (11), 6898-6910, 1999
Structural investigations of the hemoglobin of the cyanobacterium Synechocystis PCC6803 reveal a unique distal heme pocket
M Couture, TK Das, PY Savard, Y Ouellet, JB Wittenberg, BA Wittenberg, ...
European journal of biochemistry 267 (15), 4770-4780, 2000
Protein particulate detection issues in biotherapeutics development—current status
TK Das
Aaps Pharmscitech 13 (2), 732-746, 2012
Pentacoordinate hemin derivatives in sodium dodecyl sulfate micelles: model systems for the assignment of the fifth ligand in ferric heme proteins
A Boffi, TK Das, S Della Longa, C Spagnuolo, DL Rousseau
Biophysical journal 77 (2), 1143-1149, 1999
Characterization of a partially unfolded structure of cytochrome c induced by sodium dodecyl sulphate and the kinetics of its refolding
TK Das, S Mazumdar, S Mitra
European journal of biochemistry 254 (3), 662-670, 1998
The post-translational modification in cytochrome c oxidase is required to establish a functional environment of the catalytic site
TK Das, C Pecoraro, FL Tomson, RB Gennis, DL Rousseau
Biochemistry 37 (41), 14471-14476, 1998
Challenges and new frontiers in analytical characterization of antibody-drug conjugates
A Wagh, H Song, M Zeng, L Tao, TK Das
MAbs 10 (2), 222-243, 2018
Identification of the ligands to the ferric heme of Chlamydomonas chloroplast hemoglobin: evidence for ligation of tyrosine-63 (B10) to the heme
TK Das, M Couture, HC Lee, J Peisach, DL Rousseau, BA Wittenberg, ...
Biochemistry 38 (46), 15360-15368, 1999
Ligand binding in the ferric and ferrous states of Paramecium hemoglobin
TK Das, RE Weber, S Dewilde, JB Wittenberg, BA Wittenberg, ...
Biochemistry 39 (46), 14330-14340, 2000
Isomerization and oxidation in the complementarity-determining regions of a monoclonal antibody: a study of the modification–structure–function correlations by hydrogen …
Y Yan, H Wei, Y Fu, S Jusuf, M Zeng, R Ludwig, SR Krystek Jr, G Chen, ...
Analytical chemistry 88 (4), 2041-2050, 2016
The heme environment in barley hemoglobin
TK Das, HC Lee, SMG Duff, RD Hill, J Peisach, DL Rousseau, ...
Journal of Biological Chemistry 274 (7), 4207-4212, 1999
Temperature dependent quaternary state relaxation in sol–gel encapsulated hemoglobin
TK Das, I Khan, DL Rousseau, JM Friedman
Biospectroscopy 5 (S5), S64-S70, 1999
Preservation of the native structure in myoglobin at low pH by sol− gel encapsulation
TK Das, I Khan, DL Rousseau, JM Friedman
Journal of the American Chemical Society 120 (39), 10268-10269, 1998
A biopharmaceutical industry perspective on the control of visible particles in biotechnology-derived injectable drug products
S Mathonet, HC Mahler, ST Esswein, M Mazaheri, PW Cash, K Wuchner, ...
PDA Journal of Pharmaceutical Science and Technology 70 (4), 392-408, 2016
Origin of the Anomalous Fe−CO Stretching Mode in the CO Complex of Ascaris Hemoglobin
TK Das, JM Friedman, AP Kloek, DE Goldberg, DL Rousseau
Biochemistry 39 (4), 837-842, 2000
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