Folding of cytochrome c initiated by submillisecond mixing S Takahashi, SR Yeh, TK Das, CK Chan, DS Gottfried, DL Rousseau Nature structural biology 4 (1), 44-50, 1997 | 279 | 1997 |
Potential aggregation prone regions in biotherapeutics: a survey of commercial monoclonal antibodies X Wang, TK Das, SK Singh, S Kumar MAbs 1 (3), 254-267, 2009 | 221 | 2009 |
Simultaneous observation of the O—O and Fe—O2 stretching modes in oxyhemoglobins TK Das, M Couture, Y Ouellet, M Guertin, DL Rousseau Proceedings of the National Academy of Sciences 98 (2), 479-484, 2001 | 160 | 2001 |
Mutations in the putative H-channel in the cytochrome c oxidase from Rhodobacter sphaeroides show that this channel is not important for proton conduction but reveal modulation … H Lee, TK Das, DL Rousseau, D Mills, S Ferguson-Miller, RB Gennis Biochemistry 39 (11), 2989-2996, 2000 | 158 | 2000 |
Predicting solution aggregation rates for therapeutic proteins: Approaches and challenges CJ Roberts, TK Das, E Sahin International Journal of Pharmaceutics, 2011 | 152 | 2011 |
Chlamydomonas chloroplast ferrous hemoglobin: heme pocket structure and reactions with ligands M Couture, TK Das, HC Lee, J Peisach, DL Rousseau, BA Wittenberg, ... Journal of Biological Chemistry 274 (11), 6898-6910, 1999 | 146 | 1999 |
Structural investigations of the hemoglobin of the cyanobacterium Synechocystis PCC6803 reveal a unique distal heme pocket M Couture, TK Das, PY Savard, Y Ouellet, JB Wittenberg, BA Wittenberg, ... European journal of biochemistry 267 (15), 4770-4780, 2000 | 128 | 2000 |
Protein particulate detection issues in biotherapeutics development—current status TK Das Aaps Pharmscitech 13 (2), 732-746, 2012 | 117 | 2012 |
Pentacoordinate hemin derivatives in sodium dodecyl sulfate micelles: model systems for the assignment of the fifth ligand in ferric heme proteins A Boffi, TK Das, S Della Longa, C Spagnuolo, DL Rousseau Biophysical journal 77 (2), 1143-1149, 1999 | 113 | 1999 |
Characterization of a partially unfolded structure of cytochrome c induced by sodium dodecyl sulphate and the kinetics of its refolding TK Das, S Mazumdar, S Mitra European journal of biochemistry 254 (3), 662-670, 1998 | 107 | 1998 |
Challenges and new frontiers in analytical characterization of antibody-drug conjugates A Wagh, H Song, M Zeng, L Tao, TK Das MAbs 10 (2), 222-243, 2018 | 104 | 2018 |
The post-translational modification in cytochrome c oxidase is required to establish a functional environment of the catalytic site TK Das, C Pecoraro, FL Tomson, RB Gennis, DL Rousseau Biochemistry 37 (41), 14471-14476, 1998 | 99 | 1998 |
Identification of the ligands to the ferric heme of Chlamydomonas chloroplast hemoglobin: evidence for ligation of tyrosine-63 (B10) to the heme TK Das, M Couture, HC Lee, J Peisach, DL Rousseau, BA Wittenberg, ... Biochemistry 38 (46), 15360-15368, 1999 | 94 | 1999 |
Isomerization and oxidation in the complementarity-determining regions of a monoclonal antibody: a study of the modification–structure–function correlations by hydrogen … Y Yan, H Wei, Y Fu, S Jusuf, M Zeng, R Ludwig, SR Krystek Jr, G Chen, ... Analytical chemistry 88 (4), 2041-2050, 2016 | 88 | 2016 |
Ligand binding in the ferric and ferrous states of Paramecium hemoglobin TK Das, RE Weber, S Dewilde, JB Wittenberg, BA Wittenberg, ... Biochemistry 39 (46), 14330-14340, 2000 | 88 | 2000 |
The heme environment in barley hemoglobin TK Das, HC Lee, SMG Duff, RD Hill, J Peisach, DL Rousseau, ... Journal of Biological Chemistry 274 (7), 4207-4212, 1999 | 80 | 1999 |
A biopharmaceutical industry perspective on the control of visible particles in biotechnology-derived injectable drug products S Mathonet, HC Mahler, ST Esswein, M Mazaheri, PW Cash, K Wuchner, ... PDA Journal of Pharmaceutical Science and Technology 70 (4), 392-408, 2016 | 76 | 2016 |
Temperature dependent quaternary state relaxation in sol–gel encapsulated hemoglobin TK Das, I Khan, DL Rousseau, JM Friedman Biospectroscopy 5 (S5), S64-S70, 1999 | 75 | 1999 |
Preservation of the native structure in myoglobin at low pH by sol− gel encapsulation TK Das, I Khan, DL Rousseau, JM Friedman Journal of the American Chemical Society 120 (39), 10268-10269, 1998 | 75 | 1998 |
Stress factors in mAb drug substance production processes: critical assessment of impact on product quality and control strategy TK Das, LO Narhi, A Sreedhara, T Menzen, C Grapentin, DK Chou, ... Journal of Pharmaceutical Sciences 109 (1), 116-133, 2020 | 59 | 2020 |