Ofir Cohen
Ofir Cohen
Dana-Farber Caner Institute, Broad Institute, Ben Gurion University (2022)
Verified email at - Homepage
Cited by
Cited by
Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq
I Tirosh, B Izar, SM Prakadan, MH Wadsworth, D Treacy, JJ Trombetta, ...
Science 352 (6282), 189-196, 2016
Genomic correlates of immune-cell infiltrates in colorectal carcinoma
M Giannakis, XJ Mu, SA Shukla, ZR Qian, O Cohen, R Nishihara, S Bahl, ...
Cell reports 15 (4), 857-865, 2016
Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors
VA Adalsteinsson, G Ha, SS Freeman, AD Choudhury, DG Stover, ...
Nature communications 8 (1), 1324, 2017
BREX is a novel phage resistance system widespread in microbial genomes
T Goldfarb, H Sberro, E Weinstock, O Cohen, S Doron, ...
The EMBO journal 34 (2), 169-183, 2015
A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors
M Slyper, CBM Porter, O Ashenberg, J Waldman, E Drokhlyansky, ...
Nature medicine 26 (5), 792-802, 2020
FastML: a web server for probabilistic reconstruction of ancestral sequences
H Ashkenazy, O Penn, A Doron-Faigenboim, O Cohen, G Cannarozzi, ...
Nucleic acids research 40 (W1), W580-W584, 2012
Spatially organized multicellular immune hubs in human colorectal cancer
K Pelka, M Hofree, JH Chen, S Sarkizova, JD Pirl, V Jorgji, A Bejnood, ...
Cell 184 (18), 4734-4752. e20, 2021
Prevalence and mutational determinants of high tumor mutation burden in breast cancer
R Barroso-Sousa, E Jain, O Cohen, D Kim, J Buendia-Buendia, E Winer, ...
Annals of Oncology 31 (3), 387-394, 2020
Genomic analysis of 38 Legionella species identifies large and diverse effector repertoires
D Burstein, F Amaro, T Zusman, Z Lifshitz, O Cohen, JA Gilbert, T Pupko, ...
Nature genetics 48 (2), 167-175, 2016
Allele-specific chromatin recruitment and therapeutic vulnerabilities of ESR1 activating mutations
R Jeselsohn, JS Bergholz, M Pun, MI Cornwell, W Liu, A Nardone, T Xiao, ...
Cancer cell 33 (2), 173-186. e5, 2018
Acquired HER2 mutations in ER+ metastatic breast cancer confer resistance to estrogen receptor–directed therapies
U Nayar, O Cohen, C Kapstad, MS Cuoco, AG Waks, SA Wander, ...
Nature genetics 51 (2), 207-216, 2019
The genomic landscape of intrinsic and acquired resistance to cyclin-dependent kinase 4/6 inhibitors in patients with hormone receptor–positive metastatic breast cancer
SA Wander, O Cohen, X Gong, GN Johnson, JE Buendia-Buendia, ...
Cancer discovery 10 (8), 1174-1193, 2020
The complexity hypothesis revisited: connectivity rather than function constitutes a barrier to horizontal gene transfer
O Cohen, U Gophna, T Pupko
Molecular biology and evolution 28 (4), 1481-1489, 2011
KDM5 histone demethylase activity links cellular transcriptomic heterogeneity to therapeutic resistance
K Hinohara, HJ Wu, S Vigneau, TO McDonald, KJ Igarashi, KN Yamamoto, ...
Cancer cell 34 (6), 939-953. e9, 2018
Phenotypic characterization of a comprehensive set of MAPK1/ERK2 missense mutants
L Brenan, A Andreev, O Cohen, S Pantel, A Kamburov, D Cacchiarelli, ...
Cell reports 17 (4), 1171-1183, 2016
Sensitive detection of minimal residual disease in patients treated for early-stage breast cancer
HA Parsons, J Rhoades, SC Reed, G Gydush, P Ram, P Exman, K Xiong, ...
Clinical Cancer Research 26 (11), 2556-2564, 2020
Subclonal cooperation drives metastasis by modulating local and systemic immune microenvironments
M Janiszewska, DP Tabassum, Z Castaņo, S Cristea, KN Yamamoto, ...
Nature cell biology 21 (7), 879-888, 2019
Reversion and non-reversion mechanisms of resistance to PARP inhibitor or platinum chemotherapy in BRCA1/2-mutant metastatic breast cancer
AG Waks, O Cohen, B Kochupurakkal, D Kim, CE Dunn, JB Buendia, ...
Annals of Oncology 31 (5), 590-598, 2020
FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer
X Fu, R Pereira, C De Angelis, J Veeraraghavan, S Nanda, L Qin, ...
Proceedings of the National Academy of Sciences 116 (52), 26823-26834, 2019
GLOOME: gain loss mapping engine
O Cohen, H Ashkenazy, F Belinky, D Huchon, T Pupko
Bioinformatics 26 (22), 2914-2915, 2010
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