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Achala N D Punchi Hewage
Achala N D Punchi Hewage
Verified email at amgen.com
Title
Cited by
Cited by
Year
Inhibiting the BfrB:Bfd interaction in Pseudomonas aeruginosa causes irreversible iron accumulation in bacterioferritin and iron deficiency in the bacterial cytosol
K Eshelman, H Yao, AND Punchi Hewage, JJ Deay, JR Chandler, ...
Metallomics 9 (6), 646-659, 2017
462017
Small Molecule Inhibitors of the BfrB–Bfd Interaction Decrease Pseudomonas aeruginosa Fitness and Potentiate Fluoroquinolone Activity
AND Punchi Hewage, H Yao, B Nammalwar, KK Gnanasekaran, S Lovell, ...
Journal of the American Chemical Society 141 (20), 8171-8184, 2019
232019
Small Molecule Inhibitors of the Bacterioferritin (BfrB)–Ferredoxin (Bfd) Complex Kill Biofilm-Embedded Pseudomonas aeruginosa Cells
A Soldano, H Yao, AND Punchi Hewage, K Meraz, JK Annor-Gyamfi, ...
ACS infectious diseases 7 (1), 123-140, 2020
182020
Mobilization of Iron Stored in Bacterioferritin Is Required for Metabolic Homeostasis in Pseudomonas aeruginosa
AND Punchi Hewage, L Fontenot, J Guidry, T Weldeghiorghis, AK Mehta, ...
Pathogens 9 (12), 980, 2020
82020
Use of small molecule inhibitors of the bfrb: bfd interaction in biofilms
M Rivera, YAO Huili, RA Bunce, B Nammalwar, KK Gnanasekaran, ...
US Patent App. 17/502,975, 2022
2022
Role of nuclear hormone receptors in oligodendrocyte progenitor cell differentiation and myelination
A Punchi Hewage, M Hartley
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2021
2021
SMALL MOLECULE INHIBITORS OF THE BFRB:BFD INTERACTION
M RIVERA, H YAO, RA BUNCE, B NAMMALWAR, KK GNANASEKARAN, ...
WO Patent WO/2020/117,832, 2020
2020
Genetic and Chemical Intervention of the BfrB:Bfd Interaction Dysregulate Iron Homeostasis in Pseudomonas aeruginosa and Affect Its Broader Metabolism
AP Hewage
University of Kansas, 2020
2020
Small molecule inhibitors of the BfrB: Bfd interaction affect Pseudomonas aeruginosa growth by dysregulating iron homeostasis
AP Hewage, H Yao, K Gnanasekaran, S Lovell, R Bunce, S Phaniraj, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019
2019
Perturbing the BfrB: Bfd interaction of Pseudomonas aeruginosa by chemical and genetic intervention causes irreversible accumulation of iron in BfrB
AP Hewage, H Yao, K Gnanasekaran, M Lee, S Phaniraj, S Lovell, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 255, 2018
2018
Unraveling a new role for bacterioferritin (BfrB) in Pseudomonas aeruginosa: a step toward rational targeting of bacterial iron homeostasis.
H Yao, M Rivera, A Hewage
PROTEIN SCIENCE 26, 166-166, 2017
2017
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