Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology DS Kirkpatrick, NA Hathaway, J Hanna, S Elsasser, J Rush, D Finley, ... Nature cell biology 8 (7), 700-710, 2006 | 533 | 2006 |
Dynamics and memory of heterochromatin in living cells NA Hathaway, O Bell, C Hodges, EL Miller, DS Neel, GR Crabtree Cell 149 (7), 1447-1460, 2012 | 504 | 2012 |
Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation N Bardeesy, M Sinha, AF Hezel, S Signoretti, NA Hathaway, ... Nature 419 (6903), 162-167, 2002 | 488 | 2002 |
Deubiquitinating enzyme Ubp6 functions noncatalytically to delay proteasomal degradation J Hanna, NA Hathaway, Y Tone, B Crosas, S Elsasser, DS Kirkpatrick, ... Cell 127 (1), 99-111, 2006 | 450 | 2006 |
Ubiquitin chains are remodeled at the proteasome by opposing ubiquitin ligase and deubiquitinating activities B Crosas, J Hanna, DS Kirkpatrick, DP Zhang, Y Tone, NA Hathaway, ... Cell 127 (7), 1401-1413, 2006 | 378 | 2006 |
Pharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damage X Zeng, F Sigoillot, S Gaur, S Choi, KL Pfaff, DC Oh, N Hathaway, ... Cancer cell 18 (4), 382-395, 2010 | 354 | 2010 |
APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1 NV Dimova, NA Hathaway, BH Lee, DS Kirkpatrick, ML Berkowitz, ... Nature cell biology 14 (2), 168-176, 2012 | 174 | 2012 |
Stability of the proteasome can be regulated allosterically through engagement of its proteolytic active sites MF Kleijnen, J Roelofs, S Park, NA Hathaway, M Glickman, RW King, ... Nature structural & molecular biology 14 (12), 1180-1188, 2007 | 168 | 2007 |
Histone hyperacetylation disrupts core gene regulatory architecture in rhabdomyosarcoma BE Gryder, S Pomella, C Sayers, XS Wu, Y Song, AM Chiarella, S Bagchi, ... Nature genetics 51 (12), 1714-1722, 2019 | 147 | 2019 |
Nucleosome turnover regulates histone methylation patterns over the genome EJ Chory, JP Calarco, NA Hathaway, O Bell, DS Neel, GR Crabtree Molecular cell 73 (1), 61-72. e3, 2019 | 96 | 2019 |
Comprehensive nucleosome interactome screen establishes fundamental principles of nucleosome binding A Skrajna, D Goldfarb, KM Kedziora, EM Cousins, GD Grant, CJ Spangler, ... Nucleic acids research 48 (17), 9415-9432, 2020 | 86 | 2020 |
Dose-dependent activation of gene expression is achieved using CRISPR and small molecules that recruit endogenous chromatin machinery AM Chiarella, KV Butler, BE Gryder, D Lu, TA Wang, X Yu, S Pomella, ... Nature biotechnology 38 (1), 50-55, 2020 | 78 | 2020 |
LSH mediates gene repression through macroH2A deposition K Ni, J Ren, X Xu, Y He, R Finney, SMG Braun, NA Hathaway, ... Nature communications 11 (1), 5647, 2020 | 40 | 2020 |
Targeted gene repression using novel bifunctional molecules to harness endogenous histone deacetylation activity KV Butler, AM Chiarella, J Jin, NA Hathaway ACS synthetic biology 7 (1), 38-45, 2018 | 30 | 2018 |
Epigenetic control of a local chromatin landscape AM Chiarella, D Lu, NA Hathaway International journal of molecular sciences 21 (3), 943, 2020 | 29 | 2020 |
Ring finger protein 121 is a potent regulator of adeno-associated viral genome transcription VJ Madigan, JA Yuziuk, AM Chiarella, TO Tyson, RM Meganck, ... PLoS pathogens 15 (8), e1007988, 2019 | 28 | 2019 |
Deferiprone: pan-selective histone lysine demethylase inhibition activity and structure activity relationship study V Khodaverdian, S Tapadar, IA MacDonald, Y Xu, PY Ho, A Bridges, ... Scientific reports 9 (1), 4802, 2019 | 28 | 2019 |
Marker-free quantification of repair pathway utilization at Cas9-induced double-strand breaks W Feng, DA Simpson, JE Cho, J Carvajal-Garcia, CM Smith, KM Headley, ... Nucleic Acids Research 49 (9), 5095-5105, 2021 | 25 | 2021 |
Design, implementation, and outcomes of a three-week pharmacy bridging course JE McLaughlin, J Khanova, A Persky, N Hathaway, W Cox American Journal of Pharmaceutical Education 81 (7), 6313, 2017 | 24 | 2017 |
A peptidomimetic ligand targeting the chromodomain of MPP8 reveals HRP2’s association with the HUSH complex JM Waybright, SE Clinkscales, KD Barnash, GR Budziszewski, ... ACS chemical biology 16 (9), 1721-1736, 2021 | 16 | 2021 |