Nathaniel A. Hathaway
Nathaniel A. Hathaway
Associate Professor, the UNC Eshelman School of Pharmacy, Chemical Biology and Medicinal Chemistry
Verified email at - Homepage
Cited by
Cited by
Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology
DS Kirkpatrick, NA Hathaway, J Hanna, S Elsasser, J Rush, D Finley, ...
Nature cell biology 8 (7), 700-710, 2006
Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation
N Bardeesy, M Sinha, AF Hezel, S Signoretti, NA Hathaway, ...
Nature 419 (6903), 162-167, 2002
Dynamics and memory of heterochromatin in living cells
NA Hathaway, O Bell, C Hodges, EL Miller, DS Neel, GR Crabtree
Cell 149 (7), 1447-1460, 2012
Deubiquitinating enzyme Ubp6 functions noncatalytically to delay proteasomal degradation
J Hanna, NA Hathaway, Y Tone, B Crosas, S Elsasser, DS Kirkpatrick, ...
Cell 127 (1), 99-111, 2006
Ubiquitin chains are remodeled at the proteasome by opposing ubiquitin ligase and deubiquitinating activities
B Crosas, J Hanna, DS Kirkpatrick, DP Zhang, Y Tone, NA Hathaway, ...
Cell 127 (7), 1401-1413, 2006
Pharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damage
X Zeng, F Sigoillot, S Gaur, S Choi, KL Pfaff, DC Oh, N Hathaway, ...
Cancer cell 18 (4), 382-395, 2010
APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1
NV Dimova, NA Hathaway, BH Lee, DS Kirkpatrick, ML Berkowitz, ...
Nature cell biology 14 (2), 168-176, 2012
Stability of the proteasome can be regulated allosterically through engagement of its proteolytic active sites
MF Kleijnen, J Roelofs, S Park, NA Hathaway, M Glickman, RW King, ...
Nature structural & molecular biology 14 (12), 1180-1188, 2007
Histone hyperacetylation disrupts core gene regulatory architecture in rhabdomyosarcoma
BE Gryder, S Pomella, C Sayers, XS Wu, Y Song, AM Chiarella, S Bagchi, ...
Nature genetics 51 (12), 1714-1722, 2019
Nucleosome turnover regulates histone methylation patterns over the genome
EJ Chory, JP Calarco, NA Hathaway, O Bell, DS Neel, GR Crabtree
Molecular cell 73 (1), 61-72. e3, 2019
Comprehensive nucleosome interactome screen establishes fundamental principles of nucleosome binding
A Skrajna, D Goldfarb, KM Kedziora, EM Cousins, GD Grant, CJ Spangler, ...
Nucleic acids research 48 (17), 9415-9432, 2020
Dose-dependent activation of gene expression is achieved using CRISPR and small molecules that recruit endogenous chromatin machinery
AM Chiarella, KV Butler, BE Gryder, D Lu, TA Wang, X Yu, S Pomella, ...
Nature biotechnology 38 (1), 50-55, 2020
LSH mediates gene repression through macroH2A deposition
K Ni, J Ren, X Xu, Y He, R Finney, SMG Braun, NA Hathaway, ...
Nature communications 11 (1), 5647, 2020
Epigenetic control of a local chromatin landscape
AM Chiarella, D Lu, NA Hathaway
International journal of molecular sciences 21 (3), 943, 2020
Deferiprone: pan-selective histone lysine demethylase inhibition activity and structure activity relationship study
V Khodaverdian, S Tapadar, IA MacDonald, Y Xu, PY Ho, A Bridges, ...
Scientific reports 9 (1), 4802, 2019
Targeted gene repression using novel bifunctional molecules to harness endogenous histone deacetylation activity
KV Butler, AM Chiarella, J Jin, NA Hathaway
ACS synthetic biology 7 (1), 38-45, 2018
Design, implementation, and outcomes of a three-week pharmacy bridging course
JE McLaughlin, J Khanova, A Persky, N Hathaway, W Cox
American Journal of Pharmaceutical Education 81 (7), 6313, 2017
Ring finger protein 121 is a potent regulator of adeno-associated viral genome transcription
VJ Madigan, JA Yuziuk, AM Chiarella, TO Tyson, RM Meganck, ...
PLoS pathogens 15 (8), e1007988, 2019
Marker-free quantification of repair pathway utilization at Cas9-induced double-strand breaks
W Feng, DA Simpson, JE Cho, J Carvajal-Garcia, CM Smith, KM Headley, ...
Nucleic Acids Research 49 (9), 5095-5105, 2021
Tethering of Lsh at the Oct4 locus promotes gene repression associated with epigenetic changes
J Ren, NA Hathaway, GR Crabtree, K Muegge
Epigenetics 13 (2), 173-181, 2018
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