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Enzo Alessio
Enzo Alessio
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Title
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Year
Ruthenium antimetastatic agents
E Alessio, G Mestroni, A Bergamo, G Sava
Current Topics in Medicinal Chemistry 4 (15), 1525-1535, 2004
6092004
Phase I/II study with ruthenium compound NAMI-A and gemcitabine in patients with non-small cell lung cancer after first line therapy
S Leijen, SA Burgers, P Baas, D Pluim, M Tibben, E van Werkhoven, ...
Investigational new drugs 33, 201-214, 2015
4662015
Cis-and trans-dihalotetrakis (dimethyl sulfoxide) ruthenium (II) complexes (RuX2 (DMSO) 4; X= Cl, Br): synthesis, structure, and antitumor activity
E Alessio, G Mestroni, G Nardin, WM Attia, M Calligaris, G Sava, S Zorzet
Inorganic chemistry 27 (23), 4099-4106, 1988
4451988
Thirty years of the drug candidate NAMI‐A and the myths in the field of ruthenium anticancer compounds: a personal perspective
E Alessio
European Journal of Inorganic Chemistry 2017 (12), 1549-1560, 2017
3492017
NAMI-A and KP1019/1339, two iconic ruthenium anticancer drug candidates face-to-face: A case story in medicinal inorganic chemistry
E Alessio, L Messori
Molecules 24 (10), 1995, 2019
3322019
Bioinorganic medicinal chemistry
E Alessio
John Wiley & Sons, 2011
3132011
Influence of chemical stability on the activity of the antimetastasis ruthenium compound NAMI-A
G Sava, A Bergamo, S Zorzet, B Gava, C Casarsa, M Cocchietto, A Furlani, ...
European Journal of Cancer 38 (3), 427-435, 2002
3042002
Trinuclear metallacycles: Metallatriangles and much more
E Zangrando, M Casanova, E Alessio
Chemical Reviews 108 (12), 4979-5013, 2008
2932008
Ruthenium anticancer compounds: challenges and expectations
I Bratsos, S Jedner, T Gianferrara, E Alessio
Chimia 61 (11), 692-692, 2007
2892007
Synthesis and reactivity of Ru-, Os-, Rh-, and Ir-halide− sulfoxide complexes
E Alessio
Chemical reviews 104 (9), 4203-4242, 2004
2722004
Synthesis, molecular structure, and chemical behavior of hydrogen trans-bis (dimethyl sulfoxide) tetrachlororuthenate (III) and mer-trichlorotris (dimethyl sulfoxide) ruthenium …
E Alessio, G Balducci, M Calligaris, G Costa, WM Attia, G Mestroni
Inorganic Chemistry 30 (4), 609-618, 1991
2711991
In vitro cell cycle arrest, in vivo action on solid metastasizing tumors, and host toxicity of the antimetastatic drug NAMI-A and cisplatin
A Bergamo, R Gagliardi, V Scarcia, A Furlani, E Alessio, G Mestroni, ...
Journal of Pharmacology and Experimental Therapeutics 289 (1), 559-564, 1999
2701999
Pharmacological control of lung metastases of solid tumours by a novel ruthenium complex
G Sava, I Capozzi, K Clerici, G Gagliardi, E Alessio, G Mestroni
Clinical & experimental metastasis 16, 371-379, 1998
2601998
A categorization of metal anticancer compounds based on their mode of action
T Gianferrara, I Bratsos, E Alessio
Dalton Transactions, 7588-7598, 2009
2582009
Synthesis and characterization of two new classes of ruthenium (III)-sulfoxide complexes with nitrogen donor ligands (L): Na [trans-RuCl4 (R2SO)(L)] and mer, cis-RuCl3 (R2SO …
E Alessio, G Balducci, A Lutman, G Mestroni, M Calligaris, WM Attia
Inorganica Chimica Acta 203 (2), 205-217, 1993
2211993
Wavelength-dependent electron and energy transfer pathways in a side-to-face ruthenium porphyrin/perylene bisimide assembly
A Prodi, C Chiorboli, F Scandola, E Iengo, E Alessio, R Dobrawa, ...
Journal of the American Chemical Society 127 (5), 1454-1462, 2005
2172005
The hydrolysis of the anti-cancer ruthenium complex NAMI-A affects its DNA binding and antimetastatic activity: an NMR evaluation
M Bacac, ACG Hotze, K van der Schilden, JG Haasnoot, S Pacor, ...
Journal of inorganic biochemistry 98 (2), 402-412, 2004
2172004
Water-soluble ruthenium (III)-dimethyl sulfoxide complexes: chemical behaviour and pharmaceutical properties
G Mestroni, E Alessio, G Sava, S Pacor, M Coluccia, A Boccarelli
Metal-Based Drugs 1, 41-63, 1994
2051994
Treatment of metastases of solid mouse tumours by NAMI-A: comparison with cisplatin, cyclophosphamide and dacarbazine.
G Sava, R Gagliardi, A Bergamo, E Alessio, G Mestroni
Anticancer research 19 (2A), 969-972, 1999
2031999
A spectroscopic study of the reaction of NAMI, a novel ruthenium (III) anti‐neoplastic complex, with bovine serum albumin
L Messori, P Orioli, D Vullo, E Alessio, E Iengo
European journal of biochemistry 267 (4), 1206-1213, 2000
1982000
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