| Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1 DA Barbie, P Tamayo, JS Boehm, SY Kim, SE Moody, IF Dunn, ... Nature 462 (7269), 108-112, 2009 | 3076 | 2009 |
| A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen J Moffat, DA Grueneberg, X Yang, SY Kim, AM Kloepfer, G Hinkle, ... Cell 124 (6), 1283-1298, 2006 | 2018 | 2006 |
| COT drives resistance to RAF inhibition through MAP kinase pathway reactivation CM Johannessen, JS Boehm, SY Kim, SR Thomas, L Wardwell, ... Nature 468 (7326), 968-972, 2010 | 1716 | 2010 |
| SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas AJ Bass, H Watanabe, CH Mermel, S Yu, S Perner, RG Verhaak, SY Kim, ... Nature genetics 41 (11), 1238-1242, 2009 | 1057 | 2009 |
| Genetic and functional drivers of diffuse large B cell lymphoma A Reddy, J Zhang, NS Davis, AB Moffitt, CL Love, A Waldrop, S Leppa, ... Cell 171 (2), 481-494. e15, 2017 | 993 | 2017 |
| The JAK2/STAT3 signaling pathway is required for growth of CD44+CD24– stem cell–like breast cancer cells in human tumors LLC Marotta, V Almendro, A Marusyk, M Shipitsin, J Schemme, SR Walker, ... The Journal of clinical investigation 121 (7), 2723-2735, 2011 | 976 | 2011 |
| Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner A Kalender, A Selvaraj, SY Kim, P Gulati, S Brûlé, B Viollet, BE Kemp, ... Cell metabolism 11 (5), 390-401, 2010 | 973 | 2010 |
| Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase T Nobukuni, M Joaquin, M Roccio, SG Dann, SY Kim, P Gulati, MP Byfield, ... Proceedings of the National Academy of Sciences 102 (40), 14238-14243, 2005 | 952 | 2005 |
| CDK8 is a colorectal cancer oncogene that regulates β-catenin activity R Firestein, AJ Bass, SY Kim, IF Dunn, SJ Silver, I Guney, E Freed, ... Nature 455 (7212), 547-551, 2008 | 795 | 2008 |
| Integrative genomic approaches identify IKBKE as a breast cancer oncogene JS Boehm, JJ Zhao, J Yao, SY Kim, R Firestein, IF Dunn, SK Sjostrom, ... Cell 129 (6), 1065-1079, 2007 | 709 | 2007 |
| Skp2 regulates Myc protein stability and activity SY Kim, A Herbst, KA Tworkowski, SE Salghetti, WP Tansey Molecular cell 11 (5), 1177-1188, 2003 | 625 | 2003 |
| AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer KM Vasudevan, DA Barbie, MA Davies, R Rabinovsky, CJ McNear, ... Cancer cell 16 (1), 21-32, 2009 | 617 | 2009 |
| Synthetic lethal interaction between oncogenic KRAS dependency and STK33 suppression in human cancer cells C Scholl, S Fröhling, IF Dunn, AC Schinzel, DA Barbie, SY Kim, SJ Silver, ... Cell 137 (5), 821-834, 2009 | 616 | 2009 |
| Destruction of Myc by ubiquitin‐mediated proteolysis: cancer‐associated and transforming mutations stabilize Myc SE Salghetti, SY Kim, WP Tansey The EMBO journal, 1999 | 558 | 1999 |
| Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication J Méndez, XH Zou-Yang, SY Kim, M Hidaka, WP Tansey, B Stillman Molecular cell 9 (3), 481-491, 2002 | 402 | 2002 |
| RSK3/4 mediate resistance to PI3K pathway inhibitors in breast cancer V Serra, PJA Eichhorn, C García-García, YH Ibrahim, L Prudkin, ... The Journal of clinical investigation 123 (6), 2551-2563, 2013 | 147 | 2013 |
| The whole-genome landscape of Burkitt lymphoma subtypes RI Panea, CL Love, JR Shingleton, A Reddy, JA Bailey, AM Moormann, ... Blood, The Journal of the American Society of Hematology 134 (19), 1598-1607, 2019 | 138 | 2019 |
| PRKACA mediates resistance to HER2-targeted therapy in breast cancer cells and restores anti-apoptotic signaling SE Moody, AC Schinzel, S Singh, F Izzo, MR Strickland, L Luo, ... Oncogene 34 (16), 2061-2071, 2015 | 104 | 2015 |
| CK1ε is required for breast cancers dependent on β-catenin activity SY Kim, IF Dunn, R Firestein, P Gupta, L Wardwell, K Repich, AC Schinzel, ... PloS one 5 (2), e8979, 2010 | 99 | 2010 |
| Systematic Interrogation of 3q26 Identifies TLOC1 and SKIL as Cancer Drivers D Hagerstrand, A Tong, SE Schumacher, N Ilic, RR Shen, HW Cheung, ... Cancer discovery 3 (9), 1044-1057, 2013 | 86 | 2013 |
