Israel Fernandez
Israel Fernandez
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Ribosome structures to near-atomic resolution from thirty thousand cryo-EM particles
X Bai, IS Fernandez, G McMullan, SHW Scheres
elife 2, e00461, 2013
Structure of the mammalian ribosome-Sec61 complex to 3.4 Ĺ resolution
RM Voorhees, IS Fernández, SHW Scheres, RS Hegde
Cell 157 (7), 1632-1643, 2014
Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine
W Wong, X Bai, A Brown, IS Fernandez, E Hanssen, M Condron, YH Tan, ...
Elife 3, e03080, 2014
Elongation factor G bound to the ribosome in an intermediate state of translocation
DS Tourigny, IS Fernández, AC Kelley, V Ramakrishnan
Science 340 (6140), 2013
Initiation of translation by cricket paralysis virus IRES requires its translocation in the ribosome
IS Fernández, XC Bai, G Murshudov, SHW Scheres, V Ramakrishnan
Cell 157 (4), 823-831, 2014
Structural changes enable start codon recognition by the eukaryotic translation initiation complex
T Hussain, JL Llácer, IS Fernández, A Munoz, P Martin-Marcos, CG Savva, ...
Cell 159 (3), 597-607, 2014
Ribosome-dependent activation of stringent control
A Brown, IS Fernández, Y Gordiyenko, V Ramakrishnan
Nature 534 (7606), 277-280, 2016
Molecular architecture of a eukaryotic translational initiation complex
IS Fernández, XC Bai, T Hussain, AC Kelley, JR Lorsch, V Ramakrishnan, ...
Science 342 (6160), 2013
Unusual base pairing during the decoding of a stop codon by the ribosome
IS Fernández, CL Ng, AC Kelley, G Wu, YT Yu, V Ramakrishnan
Nature 500 (7460), 107-110, 2013
Gentisic acid, a compound associated with plant defense and a metabolite of aspirin, heads a new class of in vivo fibroblast growth factor inhibitors
IS Fernández, P Cuevas, J Angulo, P López-Navajas, ...
Journal of Biological Chemistry 285 (15), 11714-11729, 2010
Mefloquine targets the Plasmodium falciparum 80S ribosome to inhibit protein synthesis
W Wong, XC Bai, BE Sleebs, T Triglia, A Brown, JK Thompson, ...
Nature microbiology 2 (6), 1-9, 2017
Novel structural features in the GMC family of oxidoreductases revealed by the crystal structure of fungal aryl-alcohol oxidase
IS Fernández, FJ Ruiz-Duenas, E Santillana, P Ferreira, MJ Martínez, ...
Acta Crystallographica Section D: Biological Crystallography 65 (11), 1196-1205, 2009
The nonsense-mediated mRNA decay SMG-1 kinase is regulated by large-scale conformational changes controlled by SMG-8
E Arias-Palomo, A Yamashita, IS Fernández, R Núńez-Ramírez, Y Bamba, ...
Genes & development 25 (2), 153-164, 2011
The N-terminal acetylation of Sir3 stabilizes its binding to the nucleosome core particle
N Arnaudo, IS Fernández, SH McLaughlin, SY Peak-Chew, D Rhodes, ...
Nature structural & molecular biology 20 (9), 1119-1121, 2013
The ribosome triggers the stringent response by RelA via a highly distorted tRNA
X Agirrezabala, IS Fernández, AC Kelley, DG Cartón, V Ramakrishnan, ...
EMBO reports 14 (9), 811-816, 2013
Structural characterization of ribosome recruitment and translocation by type IV IRES
J Murray, CG Savva, BS Shin, TE Dever, V Ramakrishnan, IS Fernández
Elife 5, e13567, 2016
Heparin modulates the mitogenic activity of fibroblast growth factor by inducing dimerization of its receptor. a 3D view by using NMR
L Nieto, Á Canales, IS Fernández, E Santillana, R González‐Corrochano, ...
ChemBioChem 14 (14), 1732-1744, 2013
Characterization of SMG-9, an essential component of the nonsense-mediated mRNA decay SMG1C complex
IS Fernandez, A Yamashita, E Arias-Palomo, Y Bamba, RA Bartolome, ...
Nucleic acids research 39 (1), 347-358, 2011
Crystal Structure of Human Epidermal Kallikrein 7 (hK7) Synthesized Directly in its Native State in E. coli: Insights into the Atomic Basis of its Inhibition by LEKTI …
IS Fernández, L Ständker, HJ Mägert, WG Forssmann, ...
Journal of molecular biology 377 (5), 1488-1497, 2008
Dual tRNA mimicry in the Cricket Paralysis Virus IRES uncovers an unexpected similarity with the Hepatitis C Virus IRES
VP Pisareva, AV Pisarev, IS Fernández
Elife 7, e34062, 2018
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