Justin Yerbury
Justin Yerbury
Prof. in Neurodegenerative Disease, University of Wollongong, Illawarra Health and Medical Research
Verified email at - Homepage
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Intercellular propagated misfolding of wild-type Cu/Zn superoxide dismutase occurs via exosome-dependent and-independent mechanisms
LI Grad, JJ Yerbury, BJ Turner, WC Guest, E Pokrishevsky, MA O’Neill, ...
Proceedings of the National Academy of Sciences 111 (9), 3620-3625, 2014
ANS binding reveals common features of cytotoxic amyloid species
B Bolognesi, JR Kumita, TP Barros, EK Esbjorner, LM Luheshi, ...
ACS chemical biology 5 (8), 735-740, 2010
The extracellular chaperone clusterin influences amyloid formation and toxicity by interacting with prefibrillar structures
JJ Yerbury, S Poon, S Meehan, B Thompson, JR Kumita, CM Dobson, ...
The FASEB Journal 21 (10), 2312-2322, 2007
CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia
KL Williams, S Topp, S Yang, B Smith, JA Fifita, ST Warraich, KY Zhang, ...
Nature communications 7, 11253, 2016
Walking the tightrope: Proteostasis and neurodegenerative disease.
JJ Yerbury, L Ooi, A Dillin, DN Saunders, DM Hatters, PM Beart, ...
Journal of Neurochemistry 137 (4), 489-505, 2016
Extracellular Chaperones and Proteostasis
AR Wyatt, JJ Yerbury, H Ecroyd, MR Wilson
Annual Review of Biochemistry 82 (1), 295-322, 2013
Potential roles of abundant extracellular chaperones in the control of amyloid formation and toxicity
MR Wilson, JJ Yerbury, S Poon
Molecular BioSystems 4 (1), 42-52, 2008
Quality control of protein folding in extracellular space
JJ Yerbury, EM Stewart, AR Wyatt, MR Wilson
EMBO reports 6 (12), 1131-1136, 2005
The microglial NLRP3 inflammasome is activated by amyotrophic lateral sclerosis proteins
V Deora, JD Lee, EA Albornoz, L McAlary, CJ Jagaraj, AAB Robertson, ...
Glia 68 (2), 407-421, 2020
Clusterin facilitates in vivo clearance of extracellular misfolded proteins
AR Wyatt, JJ Yerbury, P Berghofer, I Greguric, A Katsifis, CM Dobson, ...
Cellular and Molecular Life Sciences 68, 3919-3931, 2011
Association of regulatory T-cell expansion with progression of amyotrophic lateral sclerosis: a study of humans and a transgenic mouse model
RK Sheean, FC McKay, E Cretney, CR Bye, ND Perera, D Tomas, ...
JAMA neurology 75 (6), 681-689, 2018
Distinct partitioning of ALS associated TDP-43, FUS and SOD1 mutants into cellular inclusions
NE Farrawell, IA Lambert-Smith, ST Warraich, IP Blair, DN Saunders, ...
Scientific Reports 5, 13416, 2015
Prion-like propagation of protein misfolding and aggregation in amyotrophic lateral sclerosis
L McAlary, SS Plotkin, JJ Yerbury, NR Cashman
Frontiers in molecular neuroscience 12, 262, 2019
The acute phase protein haptoglobin is a mammalian extracellular chaperone with an action similar to clusterin
JJ Yerbury, MS Rybchyn, SB Easterbrook-Smith, C Henriques, MR Wilson
Biochemistry 44 (32), 10914-10925, 2005
Disease Mechanisms in ALS: Misfolded SOD1 Transferred Through Exosome-Dependent and Exosome-Independent Pathways
JM Silverman, SM Fernando, LI Grad, AF Hill, BJ Turner, JJ Yerbury, ...
Cellular and Molecular Neurobiology 36 (3), 377-81, 2016
P2X7 receptor activation induces reactive oxygen species formation and cell death in murine EOC13 microglia
R Bartlett, JJ Yerbury, R Sluyter
Mediators of inflammation 2013, 271813, 2013
Extracellular aggregated Cu/Zn superoxide dismutase activates microglia to give a cytotoxic phenotype
K Roberts, R Zeineddine, L Corcoran, W Li, IL Campbell, JJ Yerbury
Glia 61 (3), 409-419, 2013
Protease activation of α2-macroglobulin modulates a chaperone-like action with broad specificity
K French, JJ Yerbury, MR Wilson
Biochemistry 47 (4), 1176-1185, 2008
Spinal motor neuron protein supersaturation patterns are associated with inclusion body formation in ALS
P Ciryam, IA Lambert-Smith, DM Bean, R Freer, F Cid, GG Tartaglia, ...
Proceedings of the National Academy of Sciences 114 (20), E3935–E3943, 2017
α2-Macroglobulin and haptoglobin suppress amyloid formation by interacting with prefibrillar protein species
JJ Yerbury, JR Kumita, S Meehan, CM Dobson, MR Wilson
Journal of Biological Chemistry 284 (7), 4246-4254, 2009
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