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Marie Hanscom
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Over‐expression of HSP70 attenuates caspase‐dependent and caspase‐independent pathways and inhibits neuronal apoptosis
B Sabirzhanov, BA Stoica, M Hanscom, CS Piao, AI Faden
Journal of neurochemistry 123 (4), 542-554, 2012
1432012
Bidirectional brain-gut interactions and chronic pathological changes after traumatic brain injury in mice
EL Ma, AD Smith, N Desai, L Cheung, M Hanscom, BA Stoica, DJ Loane, ...
Brain, behavior, and immunity 66, 56-69, 2017
1382017
PARP-1 inhibition attenuates neuronal loss, microglia activation and neurological deficits after traumatic brain injury
BA Stoica, DJ Loane, Z Zhao, SV Kabadi, M Hanscom, KR Byrnes, ...
Journal of Neurotrauma 31 (8), 758-772, 2014
1362014
A prominent low-pH methotrexate transport activity in human solid tumors: contribution to the preservation of methotrexate pharmacologic activity in HeLa cells lacking the …
R Zhao, F Gao, M Hanscom, ID Goldman
Clinical Cancer Research 10 (2), 718-727, 2004
1232004
Brain-gut axis dysfunction in the pathogenesis of traumatic brain injury
M Hanscom, DJ Loane, T Shea-Donohue
The Journal of Clinical Investigation 131 (12), 2021
1152021
Selective CDK inhibitor limits neuroinflammation and progressive neurodegeneration after brain trauma
SV Kabadi, BA Stoica, KR Byrnes, M Hanscom, DJ Loane, AI Faden
Journal of Cerebral Blood Flow & Metabolism 32 (1), 137-149, 2012
952012
Propofol limits microglial activation after experimental brain trauma through inhibition of nicotinamide adenine dinucleotide phosphate oxidase
T Luo, J Wu, SV Kabadi, B Sabirzhanov, K Guanciale, M Hanscom, ...
Anesthesiology 119 (6), 1370-1388, 2013
842013
Selective preservation of pemetrexed pharmacological activity in HeLa cells lacking the reduced folate carrier: association with the presence of a secondary transport pathway
R Zhao, M Hanscom, S Chattopadhyay, ID Goldman
Cancer research 64 (9), 3313-3319, 2004
722004
Sex differences in cell genesis, hippocampal volume and behavioral outcomes in a rat model of neonatal HI
J Waddell, M Hanscom, NS Edwards, MC McKenna, MM McCarthy
Experimental neurology 275, 285-295, 2016
692016
Combined inhibition of cell death induced by apoptosis inducing factor and caspases provides additive neuroprotection in experimental traumatic brain injury
CS Piao, DJ Loane, BA Stoica, S Li, M Hanscom, R Cabatbat, K Blomgren, ...
Neurobiology of disease 46 (3), 745-758, 2012
672012
Cyclin D1 gene ablation confers neuroprotection in traumatic brain injury
SV Kabadi, BA Stoica, DJ Loane, KR Byrnes, M Hanscom, RM Cabatbat, ...
Journal of neurotrauma 29 (5), 813-827, 2012
632012
Antifolate resistance in a HeLa cell line associated with impaired transport independent of the reduced folate carrier
R Zhao, S Chattopadhyay, M Hanscom, ID Goldman
Clinical cancer research 10 (24), 8735-8742, 2004
612004
Inhibition of E2F1/CDK1 Pathway Attenuates Neuronal Apoptosis In Vitro and Confers Neuroprotection after Spinal Cord Injury In Vivo
J Wu, G Kharebava, C Piao, BA Stoica, M Dinizo, B Sabirzhanov, ...
PloS one 7 (7), e42129, 2012
582012
CR8, a selective and potent CDK inhibitor, provides neuroprotection in experimental traumatic brain injury
SV Kabadi, BA Stoica, M Hanscom, DJ Loane, G Kharebava, MG Murray II, ...
Neurotherapeutics 9, 405-421, 2012
582012
Cell cycle inhibition reduces inflammatory responses, neuronal loss, and cognitive deficits induced by hypobaria exposure following traumatic brain injury
JW Skovira, J Wu, JJ Matyas, A Kumar, M Hanscom, SV Kabadi, R Fang, ...
Journal of neuroinflammation 13, 1-16, 2016
412016
Acute colitis during chronic experimental traumatic brain injury in mice induces dysautonomia and persistent extraintestinal, systemic, and CNS inflammation with exacerbated …
M Hanscom, DJ Loane, T Aubretch, J Leser, K Molesworth, N Hedgekar, ...
Journal of neuroinflammation 18, 1-31, 2021
402021
Loss of reduced folate carrier function and folate depletion result in enhanced pemetrexed inhibition of purine synthesis
R Zhao, S Zhang, M Hanscom, S Chattopadhyay, ID Goldman
Clinical cancer research 11 (3), 1294-1301, 2005
362005
Acyl-2-aminobenzimidazoles: A novel class of neuroprotective agents targeting mGluR5
X He, SK Lakkaraju, M Hanscom, Z Zhao, J Wu, B Stoica, AD MacKerell Jr, ...
Bioorganic & medicinal chemistry 23 (9), 2211-2220, 2015
282015
Positive allosteric modulators (PAMs) of metabotropic glutamate receptor 5 (mGluR5) attenuate microglial activation
F Xue, B A Stoica, M Hanscom, S V Kabadi, A I Faden
CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS …, 2014
252014
Inhibition of autophagy in microglia and macrophages exacerbates innate immune responses and worsens brain injury outcomes
N Hegdekar, C Sarkar, S Bustos, RM Ritzel, M Hanscom, P Ravishankar, ...
Autophagy 19 (7), 2026-2044, 2023
232023
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