Over‐expression of HSP70 attenuates caspase‐dependent and caspase‐independent pathways and inhibits neuronal apoptosis B Sabirzhanov, BA Stoica, M Hanscom, CS Piao, AI Faden Journal of neurochemistry 123 (4), 542-554, 2012 | 143 | 2012 |
Bidirectional brain-gut interactions and chronic pathological changes after traumatic brain injury in mice EL Ma, AD Smith, N Desai, L Cheung, M Hanscom, BA Stoica, DJ Loane, ... Brain, behavior, and immunity 66, 56-69, 2017 | 138 | 2017 |
PARP-1 inhibition attenuates neuronal loss, microglia activation and neurological deficits after traumatic brain injury BA Stoica, DJ Loane, Z Zhao, SV Kabadi, M Hanscom, KR Byrnes, ... Journal of Neurotrauma 31 (8), 758-772, 2014 | 136 | 2014 |
A prominent low-pH methotrexate transport activity in human solid tumors: contribution to the preservation of methotrexate pharmacologic activity in HeLa cells lacking the … R Zhao, F Gao, M Hanscom, ID Goldman Clinical Cancer Research 10 (2), 718-727, 2004 | 123 | 2004 |
Brain-gut axis dysfunction in the pathogenesis of traumatic brain injury M Hanscom, DJ Loane, T Shea-Donohue The Journal of Clinical Investigation 131 (12), 2021 | 115 | 2021 |
Selective CDK inhibitor limits neuroinflammation and progressive neurodegeneration after brain trauma SV Kabadi, BA Stoica, KR Byrnes, M Hanscom, DJ Loane, AI Faden Journal of Cerebral Blood Flow & Metabolism 32 (1), 137-149, 2012 | 95 | 2012 |
Propofol limits microglial activation after experimental brain trauma through inhibition of nicotinamide adenine dinucleotide phosphate oxidase T Luo, J Wu, SV Kabadi, B Sabirzhanov, K Guanciale, M Hanscom, ... Anesthesiology 119 (6), 1370-1388, 2013 | 84 | 2013 |
Selective preservation of pemetrexed pharmacological activity in HeLa cells lacking the reduced folate carrier: association with the presence of a secondary transport pathway R Zhao, M Hanscom, S Chattopadhyay, ID Goldman Cancer research 64 (9), 3313-3319, 2004 | 72 | 2004 |
Sex differences in cell genesis, hippocampal volume and behavioral outcomes in a rat model of neonatal HI J Waddell, M Hanscom, NS Edwards, MC McKenna, MM McCarthy Experimental neurology 275, 285-295, 2016 | 69 | 2016 |
Combined inhibition of cell death induced by apoptosis inducing factor and caspases provides additive neuroprotection in experimental traumatic brain injury CS Piao, DJ Loane, BA Stoica, S Li, M Hanscom, R Cabatbat, K Blomgren, ... Neurobiology of disease 46 (3), 745-758, 2012 | 67 | 2012 |
Cyclin D1 gene ablation confers neuroprotection in traumatic brain injury SV Kabadi, BA Stoica, DJ Loane, KR Byrnes, M Hanscom, RM Cabatbat, ... Journal of neurotrauma 29 (5), 813-827, 2012 | 63 | 2012 |
Antifolate resistance in a HeLa cell line associated with impaired transport independent of the reduced folate carrier R Zhao, S Chattopadhyay, M Hanscom, ID Goldman Clinical cancer research 10 (24), 8735-8742, 2004 | 61 | 2004 |
Inhibition of E2F1/CDK1 Pathway Attenuates Neuronal Apoptosis In Vitro and Confers Neuroprotection after Spinal Cord Injury In Vivo J Wu, G Kharebava, C Piao, BA Stoica, M Dinizo, B Sabirzhanov, ... PloS one 7 (7), e42129, 2012 | 58 | 2012 |
CR8, a selective and potent CDK inhibitor, provides neuroprotection in experimental traumatic brain injury SV Kabadi, BA Stoica, M Hanscom, DJ Loane, G Kharebava, MG Murray II, ... Neurotherapeutics 9, 405-421, 2012 | 58 | 2012 |
Cell cycle inhibition reduces inflammatory responses, neuronal loss, and cognitive deficits induced by hypobaria exposure following traumatic brain injury JW Skovira, J Wu, JJ Matyas, A Kumar, M Hanscom, SV Kabadi, R Fang, ... Journal of neuroinflammation 13, 1-16, 2016 | 41 | 2016 |
Acute colitis during chronic experimental traumatic brain injury in mice induces dysautonomia and persistent extraintestinal, systemic, and CNS inflammation with exacerbated … M Hanscom, DJ Loane, T Aubretch, J Leser, K Molesworth, N Hedgekar, ... Journal of neuroinflammation 18, 1-31, 2021 | 40 | 2021 |
Loss of reduced folate carrier function and folate depletion result in enhanced pemetrexed inhibition of purine synthesis R Zhao, S Zhang, M Hanscom, S Chattopadhyay, ID Goldman Clinical cancer research 11 (3), 1294-1301, 2005 | 36 | 2005 |
Acyl-2-aminobenzimidazoles: A novel class of neuroprotective agents targeting mGluR5 X He, SK Lakkaraju, M Hanscom, Z Zhao, J Wu, B Stoica, AD MacKerell Jr, ... Bioorganic & medicinal chemistry 23 (9), 2211-2220, 2015 | 28 | 2015 |
Positive allosteric modulators (PAMs) of metabotropic glutamate receptor 5 (mGluR5) attenuate microglial activation F Xue, B A Stoica, M Hanscom, S V Kabadi, A I Faden CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS …, 2014 | 25 | 2014 |
Inhibition of autophagy in microglia and macrophages exacerbates innate immune responses and worsens brain injury outcomes N Hegdekar, C Sarkar, S Bustos, RM Ritzel, M Hanscom, P Ravishankar, ... Autophagy 19 (7), 2026-2044, 2023 | 23 | 2023 |