| Succinate is an inflammatory signal that induces IL-1β through HIF-1α GM Tannahill, AM Curtis, J Adamik, EM Palsson-McDermott, ... Nature 496 (7444), 238-242, 2013 | 3398 | 2013 |
| Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction KA Fitzgerald, EM Palsson-McDermott, AG Bowie, CA Jefferies, ... Nature 413 (6851), 78-83, 2001 | 1688 | 2001 |
| Signal transduction by the lipopolysaccharide receptor, Toll‐like receptor‐4 EM Pålsson‐McDermott, LAJ O'Neill Immunology 113 (2), 153-162, 2004 | 1597 | 2004 |
| Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21 FJ Sheedy, E Palsson-McDermott, EJ Hennessy, C Martin, JJ O'leary, ... Nature immunology 11 (2), 141-147, 2010 | 1186 | 2010 |
| Pyruvate kinase M2 regulates Hif-1α activity and IL-1β induction and is a critical determinant of the warburg effect in LPS-activated macrophages EM Palsson-McDermott, AM Curtis, G Goel, MAR Lauterbach, FJ Sheedy, ... Cell metabolism 21 (1), 65-80, 2015 | 1100 | 2015 |
| The Warburg effect then and now: from cancer to inflammatory diseases EM Palsson‐McDermott, LA O'neill Bioessays 35 (11), 965-973, 2013 | 520 | 2013 |
| Targeting immunometabolism as an anti-inflammatory strategy EM Pålsson-McDermott, LAJ O’Neill Cell research 30 (4), 300-314, 2020 | 339 | 2020 |
| Metabolic modulation in macrophage effector function C Diskin, EM Pålsson-McDermott Frontiers in immunology 9, 336365, 2018 | 298 | 2018 |
| Circadian control of innate immunity in macrophages by miR-155 targeting Bmal1 AM Curtis, CT Fagundes, G Yang, EM Palsson-McDermott, P Wochal, ... Proceedings of the National Academy of Sciences 112 (23), 7231-7236, 2015 | 287 | 2015 |
| Cutting edge: Mycobacterium tuberculosis induces aerobic glycolysis in human alveolar macrophages that is required for control of intracellular bacillary replication LE Gleeson, FJ Sheedy, EM Palsson-McDermott, D Triglia, SM O’Leary, ... The Journal of Immunology 196 (6), 2444-2449, 2016 | 284 | 2016 |
| Circadian clock protein BMAL1 regulates IL-1β in macrophages via NRF2 JO Early, D Menon, CA Wyse, MP Cervantes-Silva, Z Zaslona, RG Carroll, ... Proceedings of the National Academy of Sciences 115 (36), E8460-E8468, 2018 | 275 | 2018 |
| TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88–independent TLR4 pathway EM Palsson-McDermott, SL Doyle, AF McGettrick, M Hardy, H Husebye, ... Nature immunology 10 (6), 579-586, 2009 | 221 | 2009 |
| Pharmacological activation of pyruvate kinase M2 inhibits CD4+ T cell pathogenicity and suppresses autoimmunity S Angiari, MC Runtsch, CE Sutton, EM Palsson-McDermott, B Kelly, ... Cell metabolism 31 (2), 391-405. e8, 2020 | 199 | 2020 |
| Trif-related adapter molecule is phosphorylated by PKCε during Toll-like receptor 4 signaling AF McGettrick, EK Brint, EM Palsson-McDermott, DC Rowe, ... Proceedings of the National Academy of Sciences 103 (24), 9196-9201, 2006 | 168 | 2006 |
| Pyruvate kinase M2: a potential target for regulating inflammation JC Alves-Filho, EM Pålsson-McDermott Frontiers in immunology 7, 187961, 2016 | 159 | 2016 |
| Building an immune system from nine domains EM Pålsson-McDermott, LAJ O'Neill Biochemical Society Transactions 35 (6), 1437-1444, 2007 | 158 | 2007 |
| Malonylation of GAPDH is an inflammatory signal in macrophages S Galván-Peña, RG Carroll, C Newman, EC Hinchy, ... Nature communications 10 (1), 338, 2019 | 149 | 2019 |
| Pyruvate kinase M2 is required for the expression of the immune checkpoint PD-L1 in immune cells and tumors EM Palsson-McDermott, L Dyck, Z Zasłona, D Menon, AF McGettrick, ... Frontiers in immunology 8, 1300, 2017 | 148 | 2017 |
| Ras participates in the activation of p38 MAPK by interleukin-1 by associating with IRAK, IRAK2, TRAF6, and TAK-1 EP McDermott, LAJ O'Neill Journal of Biological Chemistry 277 (10), 7808-7815, 2002 | 148 | 2002 |
| NF-κB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1 SM Miggin, E Pålsson-McDermott, A Dunne, C Jefferies, E Pinteaux, ... Proceedings of the National Academy of Sciences 104 (9), 3372-3377, 2007 | 147 | 2007 |
