Kazuhide Hayakawa
Kazuhide Hayakawa
MGH-Harvard Medical School
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Transfer of mitochondria from astrocytes to neurons after stroke
K Hayakawa, E Esposito, X Wang, Y Terasaki, Y Liu, C Xing, X Ji, EH Lo
Nature 535 (7613), 551-555, 2016
Cannabidiol Prevents Cerebral Infarction Via a Serotonergic 5-Hydroxytryptamine1A Receptor–Dependent Mechanism
K Mishima, K Hayakawa, K Abe, T Ikeda, N Egashira, K Iwasaki, ...
Stroke 36 (5), 1071-1076, 2005
Oligodendrocyte precursors induce early blood-brain barrier opening after white matter injury
JH Seo, N Miyamoto, K Hayakawa, LDD Pham, T Maki, C Ayata, KW Kim, ...
The Journal of clinical investigation 123 (2), 2013
Astrocytic high-mobility group box 1 promotes endothelial progenitor cell-mediated neurovascular remodeling during stroke recovery
K Hayakawa, LDD Pham, ZS Katusic, K Arai, EH Lo
Proceedings of the National Academy of Sciences 109 (19), 7505-7510, 2012
Inhibition of reactive astrocytes with fluorocitrate retards neurovascular remodeling and recovery after focal cerebral ischemia in mice
K Hayakawa, T Nakano, K Irie, S Higuchi, M Fujioka, K Orito, K Iwasaki, ...
Journal of Cerebral Blood Flow & Metabolism 30 (4), 871-882, 2010
Biphasic actions of HMGB1 signaling in inflammation and recovery after stroke
K Hayakawa, J Qiu, EH Lo
Annals of the New York Academy of Sciences 1207 (1), 50-57, 2010
Delayed treatment with minocycline ameliorates neurologic impairment through activated microglia expressing a high-mobility group box1–inhibiting mechanism
K Hayakawa, K Mishima, M Nozako, M Hazekawa, S Mishima, M Fujioka, ...
Stroke 39 (3), 951-958, 2008
Cannabidiol potentiates pharmacological effects of Δ9-tetrahydrocannabinol via CB1 receptor-dependent mechanism
K Hayakawa, K Mishima, M Hazekawa, K Sano, K Irie, K Orito, T Egawa, ...
Brain research 1188, 157-164, 2008
Oligodendrocyte precursor cells support blood-brain barrier integrity via TGF-β signaling
JH Seo, T Maki, M Maeda, N Miyamoto, AC Liang, K Hayakawa, ...
PloS one 9 (7), e103174, 2014
Oxidative stress interferes with white matter renewal after prolonged cerebral hypoperfusion in mice
N Miyamoto, T Maki, LDD Pham, K Hayakawa, JH Seo, ET Mandeville, ...
Stroke 44 (12), 3516-3521, 2013
Dual effects of carbon monoxide on pericytes and neurogenesis in traumatic brain injury
YK Choi, T Maki, ET Mandeville, SH Koh, K Hayakawa, K Arai, YM Kim, ...
Nature medicine 22 (11), 1335-1341, 2016
Vascular endothelial growth factor regulates the migration of oligodendrocyte precursor cells
K Hayakawa, LDD Pham, AT Som, BJ Lee, S Guo, EH Lo, K Arai
Journal of Neuroscience 31 (29), 10666-10670, 2011
Cellular mechanisms of neurovascular damage and repair after stroke
K Arai, J Lok, S Guo, K Hayakawa, C Xing, EH Lo
Journal of child neurology 26 (9), 1193-1198, 2011
ADAMTS13 gene deletion aggravates ischemic brain damage: a possible neuroprotective role of ADAMTS13 by ameliorating postischemic hypoperfusion
M Fujioka, K Hayakawa, K Mishima, A Kunizawa, K Irie, S Higuchi, ...
Blood, The Journal of the American Society of Hematology 115 (8), 1650-1653, 2010
Repeated administration of Yokukansan inhibits DOI-induced head-twitch response and decreases expression of 5-hydroxytryptamine (5-HT) 2A receptors in the prefrontal cortex
N Egashira, K Iwasaki, A Ishibashi, K Hayakawa, R Okuno, M Abe, ...
Progress in Neuro-Psychopharmacology and Biological Psychiatry 32 (6), 1516-1520, 2008
Injury and repair in the neurovascular unit
C Xing, K Hayakawa, J Lok, K Arai, EH Lo
Neurological research 34 (4), 325-330, 2012
Neuroprotective effect of γ-glutamylethylamide (theanine) on cerebral infarction in mice
N Egashira, K Hayakawa, K Mishima, H Kimura, K Iwasaki, M Fujiwara
Neuroscience letters 363 (1), 58-61, 2004
Biphasic mechanisms of neurovascular unit injury and protection in CNS diseases
T Maki, K Hayakawa, LDD Pham, C Xing, EH Lo, K Arai
CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS …, 2013
Repeated treatment with cannabidiol but not Δ9-tetrahydrocannabinol has a neuroprotective effect without the development of tolerance
K Hayakawa, K Mishima, M Nozako, A Ogata, M Hazekawa, AX Liu, ...
Neuropharmacology 52 (4), 1079-1087, 2007
Crosstalk between oligodendrocytes and cerebral endothelium contributes to vascular remodeling after white matter injury
LDD Pham, K Hayakawa, JH Seo, MN Nguyen, AT Som, BJ Lee, S Guo, ...
Glia 60 (6), 875-881, 2012
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