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Achim Aigner
Achim Aigner
Professor of Clinical Pharmacology, Leipzig University, Faculty of Medicine
Verified email at medizin.uni-leipzig.de
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Cited by
Cited by
Year
RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo
B Urban-Klein, S Werth, S Abuharbeid, F Czubayko, A Aigner
Gene therapy 12 (5), 461-466, 2005
9652005
Immunolocalization of an FGF-binding protein reveals a widespread expression pattern during different stages of mouse embryo development
A Aigner, PE Ray, F Czubayko, A Wellstein
Histochemistry and cell biology 117, 1-11, 2002
6252002
Identification of anaplastic lymphoma kinase as a receptor for the growth factor pleiotrophin
GE Stoica, A Kuo, A Aigner, I Sunitha, B Souttou, C Malerczyk, ...
Journal of Biological Chemistry 276 (20), 16772-16779, 2001
5092001
MicroRNA replacement therapy for miR-145 and miR-33a is efficacious in a model of colon carcinoma
AF Ibrahim, U Weirauch, M Thomas, A Grünweller, RK Hartmann, ...
Cancer research 71 (15), 5214-5224, 2011
4372011
Poly (vinyl alcohol) nanofibers by electrospinning as a protein delivery system and the retardation of enzyme release by additional polymer coatings
J Zeng, A Aigner, F Czubayko, T Kissel, JH Wendorff, A Greiner
Biomacromolecules 6 (3), 1484-1488, 2005
4192005
A low molecular weight fraction of polyethylenimine (PEI) displays increased transfection efficiency of DNA and siRNA in fresh or lyophilized complexes
S Werth, B Urban-Klein, L Dai, S Höbel, M Grzelinski, U Bakowsky, ...
Journal of controlled release 112 (2), 257-270, 2006
3912006
RNA Interference-Mediated Gene Silencing of Pleiotrophin Through Polyethylenimine-Complexed Small Interfering RNAs In Vivo Exerts Antitumoral Effects in …
M Grzelinski, B Urban-Klein, T Martens, K Lamszus, U Bakowsky, S Höbel, ...
Human gene therapy 17 (7), 751-766, 2006
3232006
A secreted FGF-binding protein can serve as the angiogenic switch in human cancer
F Czubayko, EDE Liaudet-Coopman, A Aigner, AT Tuveson, GJ Berchem, ...
Nature medicine 3 (10), 1137-1140, 1997
3101997
Gene silencing through RNA interference (RNAi) in vivo: strategies based on the direct application of siRNAs
A Aigner
Journal of biotechnology 124 (1), 12-25, 2006
2912006
Pleiotrophin signaling through anaplastic lymphoma kinase is rate-limiting for glioblastoma growth
C Powers, A Aigner, GE Stoica, K McDonnell, A Wellstein
Journal of Biological Chemistry 277 (16), 14153-14158, 2002
2522002
Liposome–polyethylenimine complexes for enhanced DNA and siRNA delivery
J Schäfer, S Höbel, U Bakowsky, A Aigner
Biomaterials 31 (26), 6892-6900, 2010
2292010
Polyethylenimines for RNAi-mediated gene targeting in vivo and siRNA delivery to the lung
M Günther, J Lipka, A Malek, D Gutsch, W Kreyling, A Aigner
European Journal of Pharmaceutics and Biopharmaceutics 77 (3), 438-449, 2011
2172011
Increased microtubule assembly rates influence chromosomal instability in colorectal cancer cells
N Ertych, A Stolz, A Stenzinger, W Weichert, S Kaulfuß, P Burfeind, ...
Nature cell biology 16 (8), 779-791, 2014
2162014
Delivery systems for the direct application of siRNAs to induce RNA interference (RNAi) in vivo
A Aigner
BioMed Research International 2006, 2006
2132006
Polyethylenimines for siRNA and miRNA delivery in vivo
S Höbel, A Aigner
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 5 (5 …, 2013
2102013
In vivo pharmacokinetics, tissue distribution and underlying mechanisms of various PEI (–PEG)/siRNA complexes
A Malek, O Merkel, L Fink, F Czubayko, T Kissel, A Aigner
Toxicology and applied pharmacology 236 (1), 97-108, 2009
2102009
The host defence peptide LL-37/hCAP-18 is a growth factor for lung cancer cells
J von Haussen, R Koczulla, R Shaykhiev, C Herr, O Pinkenburg, ...
Lung cancer 59 (1), 12-23, 2008
2072008
From the exposome to mechanistic understanding of chemical-induced adverse effects
BI Escher, J Hackermüller, T Polte, S Scholz, A Aigner, R Altenburger, ...
Environment international 99, 97-106, 2017
1812017
PEG grafting of polyethylenimine (PEI) exerts different effects on DNA transfection and siRNA-induced gene targeting efficacy
A Malek, F Czubayko, A Aigner
Journal of drug targeting 16 (2), 124-139, 2008
1812008
Enhancement of fibroblast growth factor (FGF) activity by an FGF-binding protein
E Tassi, A Al-Attar, A Aigner, MR Swift, K McDonnell, A Karavanov, ...
Journal of Biological Chemistry 276 (43), 40247-40253, 2001
1812001
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