Tumor-targeted chlorotoxin-coupled nanoparticles for nucleic acid delivery to glioblastoma cells: a promising system for glioblastoma treatment PM Costa, AL Cardoso, LS Mendonça, A Serani, C Custódia, ... Molecular Therapy-Nucleic Acids 2, 2013 | 116 | 2013 |
Intravenous administration of brain-targeted stable nucleic acid lipid particles alleviates Machado-Joseph disease neurological phenotype M Conceição, L Mendonça, C Nóbrega, C Gomes, P Costa, H Hirai, ... Biomaterials 82, 124-137, 2016 | 99 | 2016 |
Extracellular microRNAs exhibit sequence-dependent stability and cellular release kinetics AML Coenen-Stass, MJ Pauwels, B Hanson, C Martin Perez, ... RNA biology 16 (5), 696-706, 2019 | 63 | 2019 |
GAPDH controls extracellular vesicle biogenesis and enhances the therapeutic potential of EV mediated siRNA delivery to the brain GH Dar, CC Mendes, WL Kuan, AA Speciale, M Conceição, A Görgens, ... Nature communications 12 (1), 6666, 2021 | 57 | 2021 |
Amelioration of systemic inflammation via the display of two different decoy protein receptors on extracellular vesicles D Gupta, OPB Wiklander, A Görgens, M Conceição, G Corso, X Liang, ... Nature biomedical engineering 5 (9), 1084-1098, 2021 | 50 | 2021 |
Overexpression of mutant ataxin-3 in mouse cerebellum induces ataxia and cerebellar neuropathology C Nóbrega, I Nascimento-Ferreira, I Onofre, D Albuquerque, M Conceição, ... The Cerebellum 12, 441-455, 2013 | 45 | 2013 |
Engineered extracellular vesicle decoy receptor-mediated modulation of the IL6 trans-signalling pathway in muscle M Conceição, L Forcina, OPB Wiklander, D Gupta, JZ Nordin, B Vrellaku, ... Biomaterials 266, 120435, 2021 | 28 | 2021 |
Gene therapies for polyglutamine diseases CA Matos, V Carmona, UG Vijayakumar, S Lopes, P Albuquerque, ... Polyglutamine Disorders, 395-438, 2018 | 24 | 2018 |
Gene therapy with AR isoform 2 rescues spinal and bulbar muscular atrophy phenotype by modulating AR transcriptional activity WF Lim, M Forouhan, TC Roberts, J Dabney, R Ellerington, AA Speciale, ... Science Advances 7 (34), eabi6896, 2021 | 22 | 2021 |
Profiling of extracellular small RNAs highlights a strong bias towards non-vesicular secretion H Sork, M Conceicao, G Corso, J Nordin, YXF Lee, K Krjutskov, ... Cells 10 (6), 1543, 2021 | 14 | 2021 |
Safety profile of the intravenous administration of brain-targeted stable nucleic acid lipid particles M Conceição, L Mendonça, C Nóbrega, C Gomes, P Costa, H Hirai, ... Data in brief 6, 700-705, 2016 | 12 | 2016 |
Oral delivery of layer-by-layer coated exosomes for colitis therapy C Deng, Y Hu, M Conceição, MJA Wood, H Zhong, Y Wang, P Shao, ... Journal of Controlled Release 354, 635-650, 2023 | 6 | 2023 |
Enhancing the therapeutic potential of extracellular vesicles using peptide technology C Martin Perez, M Conceição, R Raz, MJA Wood, TC Roberts Cell Penetrating Peptides: Methods and Protocols, 119-141, 2022 | 6 | 2022 |
Engineering of extracellular vesicles for display of protein biotherapeutics D Gupta, OPB Wiklander, A Görgens, M Conceição, G Corso, X Liang, ... bioRxiv, 2020.06. 14.149823, 2020 | 6 | 2020 |
GAPDH controls extracellular vesicle biogenesis and enhances therapeutic potential of EVs in silencing the Huntingtin gene in mice via siRNA delivery GH Dar, CC Mendes, WL Kuan, M Conceição, S El-Andaloussi, I Mager, ... bioRxiv, 2020.01. 09.899880, 2020 | 5 | 2020 |
Engineered bacteria combined with doxorubicin nanoparticles suppress angiogenesis and metastasis in murine melanoma models M Yang, M Conceição, W Chen, F Yang, B Zhao, MJA Wood, L Qiu, ... Acta Biomaterialia 158, 734-746, 2023 | 4 | 2023 |
Comparison of different methods for isolating CD8+ T lymphocyte‐derived extracellular vesicles and supramolecular attack particles AK Jainarayanan, J Capera, PF Céspedes, M Conceição, ... Journal of Extracellular Biology 2 (3), e74, 2023 | 3 | 2023 |
Guttiferones: an insight into occurrence, biosynthesis, and their broad spectrum of pharmacological activities M Conceição, FP Beserra, JAA Mejia, GR Caldas, MH Tanimoto, ... Chemico-Biological Interactions 370, 110313, 2023 | 3 | 2023 |
EV-mediated promotion of myogenic differentiation is dependent on dose, collection medium, and isolation method B Hanson, I Vorobieva, W Zheng, M Conceição, Y Lomonosova, I Mäger, ... Molecular Therapy-Nucleic Acids 33, 511-528, 2023 | 2 | 2023 |
Tumor-targeted glycogen nanoparticles loaded with hemin and glucose oxidase to promote tumor synergistic therapy L Qiu, J Wang, M Conceição, S Liu, M Yang, W Chen, M Long, X Cheng, ... International Journal of Biological Macromolecules 239, 124363, 2023 | 2 | 2023 |