| Targeting Nrf2 to suppress ferroptosis and mitochondrial dysfunction in neurodegeneration M Abdalkader, R Lampinen, KM Kanninen, TM Malm, JR Liddell Frontiers in Neuroscience 12, 376739, 2018 | 333 | 2018 |
| Molecular mechanisms of cell death in neurological diseases D Moujalled, A Strasser, JR Liddell Cell Death & Differentiation 28 (7), 2029-2044, 2021 | 320 | 2021 |
| Endogenous TDP-43 localized to stress granules can subsequently form protein aggregates SJ Parker, J Meyerowitz, JL James, JR Liddell, PJ Crouch, KM Kanninen, ... Neurochemistry international 60 (4), 415-424, 2012 | 183 | 2012 |
| Oral treatment with CuII (atsm) increases mutant SOD1 in vivo but protects motor neurons and improves the phenotype of a transgenic mouse model of amyotrophic lateral sclerosis BR Roberts, NKH Lim, EJ McAllum, PS Donnelly, DJ Hare, PA Doble, ... Journal of Neuroscience 34 (23), 8021-8031, 2014 | 173 | 2014 |
| Are astrocytes the predominant cell type for activation of Nrf2 in aging and neurodegeneration? JR Liddell Antioxidants 6 (3), 65, 2017 | 158 | 2017 |
| C-Jun N-terminal kinase controls TDP-43 accumulation in stress granules induced by oxidative stress J Meyerowitz, SJ Parker, LJ Vella, DCH Ng, KA Price, JR Liddell, ... Molecular neurodegeneration 6, 1-22, 2011 | 139 | 2011 |
| An impaired mitochondrial electron transport chain increases retention of the hypoxia imaging agent diacetylbis (4-methylthiosemicarbazonato) copperII PS Donnelly, JR Liddell, SC Lim, BM Paterson, MA Cater, MS Savva, ... Proceedings of the National Academy of Sciences 109 (1), 47-52, 2012 | 119 | 2012 |
| Glutathione peroxidase 1 and glutathione are required to protect mouse astrocytes from iron‐mediated hydrogen peroxide toxicity JR Liddell, HH Hoepken, PJ Crack, SR Robinson, R Dringen Journal of neuroscience research 84 (3), 578-586, 2006 | 92 | 2006 |
| Therapeutic effects of CuII (atsm) in the SOD1-G37R mouse model of amyotrophic lateral sclerosis EJ McAllum, NKH Lim, JL Hickey, BM Paterson, PS Donnelly, QX Li, ... Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 14 (7-8), 586-590, 2013 | 82 | 2013 |
| TDP-43 mutations causing amyotrophic lateral sclerosis are associated with altered expression of RNA-binding protein hnRNP K and affect the Nrf2 antioxidant pathway D Moujalled, A Grubman, K Acevedo, S Yang, YD Ke, DM Moujalled, ... Human Molecular Genetics 26 (9), 1732-1746, 2017 | 78 | 2017 |
| Kinase inhibitor screening identifies cyclin-dependent kinases and glycogen synthase kinase 3 as potential modulators of TDP-43 cytosolic accumulation during cell stress D Moujalled, JL James, SJ Parker, GE Lidgerwood, C Duncan, ... PloS one 8 (6), e67433, 2013 | 66 | 2013 |
| Nexus between mitochondrial function, iron, copper and glutathione in Parkinson's disease JR Liddell, AR White Neurochemistry international 117, 126-138, 2018 | 65 | 2018 |
| Glutathione peroxidase 1 and a high cellular glutathione concentration are essential for effective organic hydroperoxide detoxification in astrocytes JR Liddell, R Dringen, PJ Crack, SR Robinson Glia 54 (8), 873-879, 2006 | 61 | 2006 |
| Profiling the iron, copper and zinc content in primary neuron and astrocyte cultures by rapid online quantitative size exclusion chromatography-inductively coupled plasma-mass … DJ Hare, A Grubman, TM Ryan, A Lothian, JR Liddell, R Grimm, ... Metallomics 5 (12), 1656-1662, 2013 | 58 | 2013 |
| Circumventing the Crabtree Effect: A method to induce lactate consumption and increase oxidative phosphorylation in cell culture AI Mot, JR Liddell, AR White, PJ Crouch The International Journal of Biochemistry & Cell Biology 79, 128-138, 2016 | 55 | 2016 |
| Phosphorylation of hnRNP K by cyclin-dependent kinase 2 controls cytosolic accumulation of TDP-43 D Moujalled, JL James, S Yang, K Zhang, C Duncan, DM Moujalled, ... Human molecular genetics 24 (6), 1655-1669, 2015 | 54 | 2015 |
| The challenges of using a copper fluorescent sensor (CS1) to track intracellular distributions of copper in neuronal and glial cells KA Price, JL Hickey, Z Xiao, AG Wedd, SA James, JR Liddell, PJ Crouch, ... Chemical Science 3 (9), 2748-2759, 2012 | 53 | 2012 |
| Localized changes to glycogen synthase kinase-3 and collapsin response mediator protein-2 in the Huntington's disease affected brain NKH Lim, LW Hung, TY Pang, CA Mclean, JR Liddell, JB Hilton, QX Li, ... Human Molecular Genetics 23 (15), 4051-4063, 2014 | 52 | 2014 |
| Inhibition of TDP-43 Accumulation by Bis(thiosemicarbazonato)-Copper Complexes SJ Parker, J Meyerowitz, JL James, JR Liddell, T Nonaka, M Hasegawa, ... Public Library of Science 7 (8), e42277, 2012 | 51 | 2012 |
| Neuroprotective copper bis (thiosemicarbazonato) complexes promote neurite elongation L Bica, JR Liddell, PS Donnelly, C Duncan, A Caragounis, I Volitakis, ... PLoS One 9 (2), e90070, 2014 | 49 | 2014 |
