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Yu Zheng
Yu Zheng
MGH Cancer Center, Harvard Medical School
Verified email at mgh.harvard.edu
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Cited by
Year
RNA-Seq of single prostate CTCs implicates noncanonical Wnt signaling in antiandrogen resistance
DT Miyamoto, Y Zheng, BS Wittner, RJ Lee, H Zhu, KT Broderick, R Desai, ...
Science 349 (6254), 1351-1356, 2015
7102015
HER2 expression identifies dynamic functional states within circulating breast cancer cells
NV Jordan, A Bardia, BS Wittner, C Benes, M Ligorio, Y Zheng, M Yu, ...
Nature 537 (7618), 102-106, 2016
3952016
Genomic instability is induced by persistent proliferation of cells undergoing epithelial-to-mesenchymal transition
V Comaills, L Kabeche, R Morris, R Buisson, M Yu, MW Madden, ...
Cell reports 17 (10), 2632-2647, 2016
1212016
An RNA-based digital circulating tumor cell signature is predictive of drug response and early dissemination in prostate cancer
DT Miyamoto, RJ Lee, M Kalinich, JA LiCausi, Y Zheng, T Chen, ...
Cancer discovery 8 (3), 288-303, 2018
1182018
Expression of β-globin by cancer cells promotes cell survival during blood-borne dissemination
Y Zheng, DT Miyamoto, BS Wittner, JP Sullivan, N Aceto, NV Jordan, ...
Nature communications 8 (1), 14344, 2017
1142017
FoxM1 in Tumorigenicity of the Neuroblastoma Cells and Renewal of the Neural Progenitors
Z Wang, HJ Park, JR Carr, Y Chen, Y Zheng, J Li, AL Tyner, RH Costa, ...
Cancer research 71 (12), 4292-4302, 2011
902011
Protein tyrosine kinase 6 directly phosphorylates AKT and promotes AKT activation in response to epidermal growth factor
Y Zheng, M Peng, Z Wang, JM Asara, AL Tyner
Molecular and cellular biology, 2010
812010
AR expression in breast cancer CTCs associates with bone metastases
N Aceto, A Bardia, BS Wittner, MC Donaldson, R O'Keefe, A Engstrom, ...
Molecular Cancer Research 16 (4), 720-727, 2018
792018
Identification of β-catenin as a target of the intracellular tyrosine kinase PTK6
HL Palka-Hamblin, JJ Gierut, W Bie, PM Brauer, Y Zheng, JM Asara, ...
Journal of cell science 123 (2), 236-245, 2010
762010
Protein tyrosine kinase 6 protects cells from anoikis by directly phosphorylating focal adhesion kinase and activating AKT
Y Zheng, J Gierut, Z Wang, J Miao, JM Asara, AL Tyner
Oncogene 32 (36), 4304-4312, 2013
662013
PTK6 activation at the membrane regulates epithelial–mesenchymal transition in prostate cancer
Y Zheng, Z Wang, W Bie, PM Brauer, BE Perez White, J Li, V Nogueira, ...
Cancer research 73 (17), 5426-5437, 2013
562013
Protein-tyrosine kinase 6 promotes peripheral adhesion complex formation and cell migration by phosphorylating p130 CRK-associated substrate
Y Zheng, JM Asara, AL Tyner
Journal of Biological Chemistry 287 (1), 148-158, 2012
482012
COX-2 mediates tumor-stromal prolactin signaling to initiate tumorigenesis
Y Zheng, V Comaills, R Burr, G Boulay, DT Miyamoto, BS Wittner, ...
Proceedings of the National Academy of Sciences 116 (12), 5223-5232, 2019
462019
Context‐specific protein tyrosine kinase 6 (PTK 6) signalling in prostate cancer
Y Zheng, AL Tyner
European journal of clinical investigation 43 (4), 397-404, 2013
402013
Cytoplasmic retention of protein tyrosine kinase 6 promotes growth of prostate tumor cells
PM Brauer, Y Zheng, L Wang, A Tyner
Cell cycle 9 (20), 4190-4199, 2010
332010
The alternative splice variant of protein tyrosine kinase 6 negatively regulates growth and enhances PTK6-mediated inhibition of β-catenin
PM Brauer, Y Zheng, MD Evans, C Dominguez-Brauer, DM Peehl, ...
PloS one 6 (3), e14789, 2011
302011
Targeting FoxM1 effectively retards p53-null lymphoma and sarcoma
Z Wang, Y Zheng, HJ Park, J Li, JR Carr, Y Chen, MM Kiefer, D Kopanja, ...
Molecular cancer therapeutics 12 (5), 759-767, 2013
232013
Disruption of the mouse protein tyrosine kinase 6 gene prevents STAT3 activation and confers resistance to azoxymethane
J Gierut, Y Zheng, W Bie, RE Carroll, S Ball-Kell, A Haegebarth, AL Tyner
Gastroenterology 141 (4), 1371-1380. e2, 2011
222011
Clinicopathological characteristics of localized prostate cancer in younger men aged≤ 50 years treated with radical prostatectomy in the PSA era: A systematic review and meta …
Y Zheng, SX Lin, S Wu, DM Dahl, ML Blute, WD Zhong, X Zhou, CL Wu
Cancer medicine 9 (18), 6473-6484, 2020
132020
Functions of p21 and p27 in the regenerating epithelial linings of the mouse small and large intestine
Y Zheng, W Bie, R Yang, AO Perekatt, AJ Poole, AL Tyner
Cancer biology & therapy 7 (6), 873-879, 2008
82008
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