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Sarel Fleishman
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ROSETTA3: an object-oriented software suite for the simulation and design of macromolecules
A Leaver-Fay, M Tyka, SM Lewis, OF Lange, J Thompson, R Jacak, ...
Methods in enzymology 487, 545-574, 2011
19692011
Computational design of proteins targeting the conserved stem region of influenza hemagglutinin
SJ Fleishman, TA Whitehead, DC Ekiert, C Dreyfus, JE Corn, EM Strauch, ...
Science 332 (6031), 816-821, 2011
6962011
RosettaScripts: a scripting language interface to the Rosetta macromolecular modeling suite
SJ Fleishman, A Leaver-Fay, JE Corn, EM Strauch, SD Khare, N Koga, ...
PloS one 6 (6), e20161, 2011
6122011
High-resolution mapping of protein sequence-function relationships
DM Fowler, CL Araya, SJ Fleishman, EH Kellogg, JJ Stephany, D Baker, ...
Nature methods 7 (9), 741-746, 2010
6042010
Automated structure-and sequence-based design of proteins for high bacterial expression and stability
A Goldenzweig, M Goldsmith, SE Hill, O Gertman, P Laurino, Y Ashani, ...
Molecular cell 63 (2), 337-346, 2016
4862016
Optimization of affinity, specificity and function of designed influenza inhibitors using deep sequencing
TA Whitehead, A Chevalier, Y Song, C Dreyfus, SJ Fleishman, ...
Nature biotechnology 30 (6), 543-548, 2012
4462012
A putative molecular-activation switch in the transmembrane domain of erbB2
SJ Fleishman, J Schlessinger, N Ben-Tal
Proceedings of the National Academy of Sciences 99 (25), 15937-15940, 2002
3342002
Comment on" Network motifs: simple building blocks of complex networks" and" Superfamilies of evolved and designed networks"
Y Artzy-Randrup, SJ Fleishman, N Ben-Tal, L Stone
science 305 (5687), 1107-1107, 2004
3302004
Dominant mutations in the autoimmune regulator AIRE are associated with common organ-specific autoimmune diseases
BE Oftedal, A Hellesen, MM Erichsen, E Bratland, A Vardi, J Perheentupa, ...
Immunity 42 (6), 1185-1196, 2015
2642015
Principles of protein stability and their application in computational design
A Goldenzweig, SJ Fleishman
Annual review of biochemistry 87 (1), 105-129, 2018
2432018
Automated design of efficient and functionally diverse enzyme repertoires
O Khersonsky, R Lipsh, Z Avizemer, Y Ashani, M Goldsmith, H Leader, ...
Molecular cell 72 (1), 178-186. e5, 2018
2092018
Community-wide assessment of protein-interface modeling suggests improvements to design methodology
SJ Fleishman, TA Whitehead, EM Strauch, JE Corn, S Qin, HX Zhou, ...
Journal of molecular biology 414 (2), 289-302, 2011
1572011
Quasi-symmetry in the cryo-EM structure of EmrE provides the key to modeling its transmembrane domain
SJ Fleishman, SE Harrington, A Enosh, D Halperin, CG Tate, N Ben-Tal
Journal of molecular biology 364 (1), 54-67, 2006
1452006
Principles for computational design of binding antibodies
D Baran, MG Pszolla, GD Lapidoth, C Norn, O Dym, T Unger, S Albeck, ...
Proceedings of the National Academy of Sciences 114 (41), 10900-10905, 2017
1432017
Free diffusion of steroid hormones across biomembranes: a simplex search with implicit solvent model calculations
I Oren, SJ Fleishman, A Kessel, N Ben-Tal
Biophysical journal 87 (2), 768-779, 2004
1342004
Design and in vitro realization of carbon-conserving photorespiration
DL Trudeau, C Edlich-Muth, J Zarzycki, M Scheffen, M Goldsmith, ...
Proceedings of the National Academy of Sciences 115 (49), E11455-E11464, 2018
1332018
A Cα model for the transmembrane α helices of gap junction intercellular channels
SJ Fleishman, VM Unger, M Yeager, N Ben-Tal
Molecular cell 15 (6), 879-888, 2004
1312004
The structural and energetic basis for high selectivity in a high-affinity protein-protein interaction
NAG Meenan, A Sharma, SJ Fleishman, CJ MacDonald, B Morel, ...
Proceedings of the National Academy of Sciences 107 (22), 10080-10085, 2010
1252010
Computational design of a protein-based enzyme inhibitor
E Procko, R Hedman, K Hamilton, J Seetharaman, SJ Fleishman, M Su, ...
Journal of molecular biology 425 (18), 3563-3575, 2013
1162013
Role of the biomolecular energy gap in protein design, structure, and evolution
SJ Fleishman, D Baker
Cell 149 (2), 262-273, 2012
1162012
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