עקוב אחר
Lewis Cantley
Lewis Cantley
Dana Farber Cancer Center and Harvard Medical School
כתובת אימייל מאומתת בדומיין med.cornell.edu
כותרת
צוטט על ידי
צוטט על ידי
שנה
Understanding the Warburg effect: the metabolic requirements of cell proliferation
MG Vander Heiden, LC Cantley, CB Thompson
science 324 (5930), 1029-1033, 2009
162832009
AKT/PKB signaling: navigating downstream
BD Manning, LC Cantley
Cell 129 (7), 1261-1274, 2007
73012007
The phosphoinositide 3-kinase pathway
LC Cantley
Science 296 (5573), 1655-1657, 2002
72742002
MET Amplification Leads to Gefitinib Resistance in Lung Cancer by Activating ERBB3 Signaling
JA Engelman, K Zejnullahu, T Mitsudomi, Y Song, C Hyland, JO Park, ...
science 316 (5827), 1039-1043, 2007
54282007
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
L Dang, DW White, S Gross, BD Bennett, MA Bittinger, EM Driggers, ...
Nature 462 (7274), 739-744, 2009
45852009
The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism
JA Engelman, J Luo, LC Cantley
Nature Reviews Genetics 7 (8), 606-619, 2006
39192006
SH2 domains recognize specific phosphopeptide sequences
S Zhou, SE Shoelson, M Chaudhuri, G Gish, T Pawson, WG Haser, F King, ...
Cell 72 (5), 767-778, 1993
35681993
Oncogenes and signal transduction
LC Cantley, KR Auger, C Carpenter, B Duckworth, A Graziani, R Kapeller, ...
Cell 64 (2), 281-302, 1991
35521991
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
HR Christofk, MG Vander Heiden, MH Harris, A Ramanathan, ...
Nature 452 (7184), 230-233, 2008
31692008
Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
GM DeNicola, FA Karreth, TJ Humpton, A Gopinathan, C Wei, K Frese, ...
Nature 475 (7354), 106-109, 2011
2770*2011
New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway
LC Cantley, BG Neel
Proceedings of the National Academy of Sciences 96 (8), 4240-4245, 1999
27511999
Ras, PI (3) K and mTOR signalling controls tumour cell growth
RJ Shaw, LC Cantley
Nature 441 (7092), 424-430, 2006
26152006
PI3K pathway alterations in cancer: variations on a theme
TL Yuan, LC Cantley
Oncogene 27 (41), 5497-5510, 2008
23562008
The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin
RJ Shaw, KA Lamia, D Vasquez, SH Koo, N Bardeesy, RA DePinho, ...
Science 310 (5754), 1642-1646, 2005
23482005
PI3K: downstream AKTion blocks apoptosis
TF Franke, DR Kaplan, LC Cantley
Cell 88 (4), 435-437, 1997
21741997
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress
RJ Shaw, M Kosmatka, N Bardeesy, RL Hurley, LA Witters, RA DePinho, ...
Proceedings of the National Academy of Sciences 101 (10), 3329-3335, 2004
21302004
Phosphoinositide kinases
DA Fruman, RE Meyers, LC Cantley
Annual review of biochemistry 67 (1), 481-507, 1998
21231998
The PI3K pathway in human disease
DA Fruman, H Chiu, BD Hopkins, S Bagrodia, LC Cantley, RT Abraham
Cell 170 (4), 605-635, 2017
21192017
The structural basis for 14-3-3: phosphopeptide binding specificity
MB Yaffe, K Rittinger, S Volinia, PR Caron, A Aitken, H Leffers, ...
Cell 91 (7), 961-971, 1997
19871997
Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs
JC Obenauer, LC Cantley, MB Yaffe
Nucleic acids research 31 (13), 3635-3641, 2003
19722003
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מאמרים 1–20