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Emma C Josefsson
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The dendritic cell receptor Clec9A binds damaged cells via exposed actin filaments
JG Zhang, PE Czabotar, AN Policheni, I Caminschi, S San Wan, ...
Immunity 36 (4), 646-657, 2012
3712012
Two distinct pathways regulate platelet phosphatidylserine exposure and procoagulant function
SM Schoenwaelder, Y Yuan, EC Josefsson, MJ White, Y Yao, KD Mason, ...
Blood, The Journal of the American Society of Hematology 114 (3), 663-666, 2009
3492009
Bcl-xL–inhibitory BH3 mimetics can induce a transient thrombocytopathy that undermines the hemostatic function of platelets
SM Schoenwaelder, KE Jarman, EE Gardiner, M Hua, J Qiao, MJ White, ...
Blood, The Journal of the American Society of Hematology 118 (6), 1663-1674, 2011
3372011
Glycosylation restores survival of chilled blood platelets
KM Hoffmeister, EC Josefsson, NA Isaac, H Clausen, JH Hartwig, ...
Science 301 (5639), 1531-1534, 2003
3272003
Dual roles for hepatic lectin receptors in the clearance of chilled platelets
V Rumjantseva, PK Grewal, HH Wandall, EC Josefsson, AL Sørensen, ...
Nature medicine 15 (11), 1273-1280, 2009
2582009
Desialylation accelerates platelet clearance after refrigeration and initiates GPIbα metalloproteinase-mediated cleavage in mice
AJG Jansen, EC Josefsson, V Rumjantseva, QP Liu, H Falet, ...
Blood, The Journal of the American Society of Hematology 119 (5), 1263-1273, 2012
2252012
The pseudokinase MLKL and the kinase RIPK3 have distinct roles in autoimmune disease caused by loss of death-receptor-induced apoptosis
S Alvarez-Diaz, CP Dillon, N Lalaoui, MC Tanzer, DA Rodriguez, A Lin, ...
Immunity 45 (3), 513-526, 2016
2122016
Megakaryocytes possess a functional intrinsic apoptosis pathway that must be restrained to survive and produce platelets
EC Josefsson, C James, KJ Henley, MA Debrincat, KL Rogers, ...
Journal of Experimental Medicine 208 (10), 2017-2031, 2011
2072011
Mpl expression on megakaryocytes and platelets is dispensable for thrombopoiesis but essential to prevent myeloproliferation
AP Ng, M Kauppi, D Metcalf, CD Hyland, EC Josefsson, M Lebois, ...
Proceedings of the National Academy of Sciences 111 (16), 5884-5889, 2014
1522014
Deciphering the molecular and biologic processes that mediate histone deacetylase inhibitor–induced thrombocytopenia
MJ Bishton, SJ Harrison, BP Martin, N McLaughlin, C James, ...
Blood, The Journal of the American Society of Hematology 117 (13), 3658-3668, 2011
1442011
The macrophage αMβ2 integrin αM lectin domain mediates the phagocytosis of chilled platelets
EC Josefsson, HH Gebhard, TP Stossel, JH Hartwig, KM Hoffmeister
Journal of Biological Chemistry 280 (18), 18025-18032, 2005
1152005
Dual requirement for the ETS transcription factors Fli-1 and Erg in hematopoietic stem cells and the megakaryocyte lineage
EA Kruse, SJ Loughran, TM Baldwin, EC Josefsson, S Ellis, DK Watson, ...
Proceedings of the National Academy of Sciences 106 (33), 13814-13819, 2009
1132009
Regulation of platelet lifespan by apoptosis
M Lebois, EC Josefsson
Platelets 27 (6), 497-504, 2016
1102016
The origin and function of platelet glycosyltransferases
HH Wandall, V Rumjantseva, ALT Sørensen, S Patel-Hett, EC Josefsson, ...
Blood, The Journal of the American Society of Hematology 120 (3), 626-635, 2012
1062012
Mcl-1 and Bcl-xL coordinately regulate megakaryocyte survival
MA Debrincat, EC Josefsson, C James, KJ Henley, S Ellis, M Lebois, ...
Blood, The Journal of the American Society of Hematology 119 (24), 5850-5858, 2012
902012
Platelet production proceeds independently of the intrinsic and extrinsic apoptosis pathways
EC Josefsson, DL Burnett, M Lebois, MA Debrincat, MJ White, KJ Henley, ...
Nature communications 5 (1), 3455, 2014
892014
Polycomb repressive complex 2 component Suz12 is required for hematopoietic stem cell function and lymphopoiesis
SCW Lee, S Miller, C Hyland, M Kauppi, M Lebois, L Di Rago, D Metcalf, ...
Blood, The Journal of the American Society of Hematology 126 (2), 167-175, 2015
872015
Caspase-9 mediates the apoptotic death of megakaryocytes and platelets, but is dispensable for their generation and function
MJ White, SM Schoenwaelder, EC Josefsson, KE Jarman, KJ Henley, ...
Blood, The Journal of the American Society of Hematology 119 (18), 4283-4290, 2012
852012
BCL-2 is dispensable for thrombopoiesis and platelet survival
MA Debrincat, I Pleines, M Lebois, RM Lane, ML Holmes, J Corbin, ...
Cell death & disease 6 (4), e1721-e1721, 2015
832015
A lineage of diploid platelet-forming cells precedes polyploid megakaryocyte formation in the mouse embryo
KS Potts, TJ Sargeant, JF Markham, W Shi, C Biben, EC Josefsson, ...
Blood, The Journal of the American Society of Hematology 124 (17), 2725-2729, 2014
782014
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