The dendritic cell receptor Clec9A binds damaged cells via exposed actin filaments JG Zhang, PE Czabotar, AN Policheni, I Caminschi, S San Wan, ... Immunity 36 (4), 646-657, 2012 | 371 | 2012 |
Two distinct pathways regulate platelet phosphatidylserine exposure and procoagulant function SM Schoenwaelder, Y Yuan, EC Josefsson, MJ White, Y Yao, KD Mason, ... Blood, The Journal of the American Society of Hematology 114 (3), 663-666, 2009 | 349 | 2009 |
Bcl-xL–inhibitory BH3 mimetics can induce a transient thrombocytopathy that undermines the hemostatic function of platelets SM Schoenwaelder, KE Jarman, EE Gardiner, M Hua, J Qiao, MJ White, ... Blood, The Journal of the American Society of Hematology 118 (6), 1663-1674, 2011 | 337 | 2011 |
Glycosylation restores survival of chilled blood platelets KM Hoffmeister, EC Josefsson, NA Isaac, H Clausen, JH Hartwig, ... Science 301 (5639), 1531-1534, 2003 | 327 | 2003 |
Dual roles for hepatic lectin receptors in the clearance of chilled platelets V Rumjantseva, PK Grewal, HH Wandall, EC Josefsson, AL Sørensen, ... Nature medicine 15 (11), 1273-1280, 2009 | 258 | 2009 |
Desialylation accelerates platelet clearance after refrigeration and initiates GPIbα metalloproteinase-mediated cleavage in mice AJG Jansen, EC Josefsson, V Rumjantseva, QP Liu, H Falet, ... Blood, The Journal of the American Society of Hematology 119 (5), 1263-1273, 2012 | 225 | 2012 |
The pseudokinase MLKL and the kinase RIPK3 have distinct roles in autoimmune disease caused by loss of death-receptor-induced apoptosis S Alvarez-Diaz, CP Dillon, N Lalaoui, MC Tanzer, DA Rodriguez, A Lin, ... Immunity 45 (3), 513-526, 2016 | 212 | 2016 |
Megakaryocytes possess a functional intrinsic apoptosis pathway that must be restrained to survive and produce platelets EC Josefsson, C James, KJ Henley, MA Debrincat, KL Rogers, ... Journal of Experimental Medicine 208 (10), 2017-2031, 2011 | 207 | 2011 |
Mpl expression on megakaryocytes and platelets is dispensable for thrombopoiesis but essential to prevent myeloproliferation AP Ng, M Kauppi, D Metcalf, CD Hyland, EC Josefsson, M Lebois, ... Proceedings of the National Academy of Sciences 111 (16), 5884-5889, 2014 | 152 | 2014 |
Deciphering the molecular and biologic processes that mediate histone deacetylase inhibitor–induced thrombocytopenia MJ Bishton, SJ Harrison, BP Martin, N McLaughlin, C James, ... Blood, The Journal of the American Society of Hematology 117 (13), 3658-3668, 2011 | 144 | 2011 |
The macrophage αMβ2 integrin αM lectin domain mediates the phagocytosis of chilled platelets EC Josefsson, HH Gebhard, TP Stossel, JH Hartwig, KM Hoffmeister Journal of Biological Chemistry 280 (18), 18025-18032, 2005 | 115 | 2005 |
Dual requirement for the ETS transcription factors Fli-1 and Erg in hematopoietic stem cells and the megakaryocyte lineage EA Kruse, SJ Loughran, TM Baldwin, EC Josefsson, S Ellis, DK Watson, ... Proceedings of the National Academy of Sciences 106 (33), 13814-13819, 2009 | 113 | 2009 |
Regulation of platelet lifespan by apoptosis M Lebois, EC Josefsson Platelets 27 (6), 497-504, 2016 | 110 | 2016 |
The origin and function of platelet glycosyltransferases HH Wandall, V Rumjantseva, ALT Sørensen, S Patel-Hett, EC Josefsson, ... Blood, The Journal of the American Society of Hematology 120 (3), 626-635, 2012 | 106 | 2012 |
Mcl-1 and Bcl-xL coordinately regulate megakaryocyte survival MA Debrincat, EC Josefsson, C James, KJ Henley, S Ellis, M Lebois, ... Blood, The Journal of the American Society of Hematology 119 (24), 5850-5858, 2012 | 90 | 2012 |
Platelet production proceeds independently of the intrinsic and extrinsic apoptosis pathways EC Josefsson, DL Burnett, M Lebois, MA Debrincat, MJ White, KJ Henley, ... Nature communications 5 (1), 3455, 2014 | 89 | 2014 |
Polycomb repressive complex 2 component Suz12 is required for hematopoietic stem cell function and lymphopoiesis SCW Lee, S Miller, C Hyland, M Kauppi, M Lebois, L Di Rago, D Metcalf, ... Blood, The Journal of the American Society of Hematology 126 (2), 167-175, 2015 | 87 | 2015 |
Caspase-9 mediates the apoptotic death of megakaryocytes and platelets, but is dispensable for their generation and function MJ White, SM Schoenwaelder, EC Josefsson, KE Jarman, KJ Henley, ... Blood, The Journal of the American Society of Hematology 119 (18), 4283-4290, 2012 | 85 | 2012 |
BCL-2 is dispensable for thrombopoiesis and platelet survival MA Debrincat, I Pleines, M Lebois, RM Lane, ML Holmes, J Corbin, ... Cell death & disease 6 (4), e1721-e1721, 2015 | 83 | 2015 |
A lineage of diploid platelet-forming cells precedes polyploid megakaryocyte formation in the mouse embryo KS Potts, TJ Sargeant, JF Markham, W Shi, C Biben, EC Josefsson, ... Blood, The Journal of the American Society of Hematology 124 (17), 2725-2729, 2014 | 78 | 2014 |