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Alejandro Gutierrez
Alejandro Gutierrez
Boston Children's Hospital
Verified email at childrens.harvard.edu
Title
Cited by
Cited by
Year
An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element
MR Mansour, BJ Abraham, L Anders, A Berezovskaya, A Gutierrez, ...
Science 346 (6215), 1373-1377, 2014
6382014
SCFFBW7 regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction
H Inuzuka, S Shaik, I Onoyama, D Gao, A Tseng, RS Maser, B Zhai, ...
Nature 471 (7336), 104-109, 2011
6172011
High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia
A Gutierrez, T Sanda, R Grebliunaite, A Carracedo, L Salmena, Y Ahn, ...
Blood, The Journal of the American Society of Hematology 114 (3), 647-650, 2009
4482009
Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers
RS Maser, B Choudhury, PJ Campbell, B Feng, KK Wong, A Protopopov, ...
Nature 447 (7147), 966-971, 2007
4202007
An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia
B Knoechel, JE Roderick, KE Williamson, J Zhu, JG Lohr, MJ Cotton, ...
Nature genetics 46 (4), 364-370, 2014
3122014
Core transcriptional regulatory circuit controlled by the TAL1 complex in human T cell acute lymphoblastic leukemia
T Sanda, LN Lawton, MI Barrasa, ZP Fan, H Kohlhammer, A Gutierrez, ...
Cancer cell 22 (2), 209-221, 2012
2822012
The public repository of xenografts enables discovery and randomized phase II-like trials in mice
EC Townsend, MA Murakami, A Christodoulou, AL Christie, J Köster, ...
Cancer cell 29 (4), 574-586, 2016
2492016
Liquid chromatography/electron capture atmospheric pressure chemical ionization/mass spectrometry: analysis of pentafluorobenzyl derivatives of biomolecules and drugs in the …
G Singh, A Gutierrez, K Xu, IA Blair
Analytical chemistry 72 (14), 3007-3013, 2000
2352000
An “off-the-shelf” fratricide-resistant CAR-T for the treatment of T cell hematologic malignancies
ML Cooper, J Choi, K Staser, JK Ritchey, JM Devenport, K Eckardt, ...
Leukemia 32 (9), 1970-1983, 2018
1942018
Maturation stage of T-cell acute lymphoblastic leukemia determines BCL-2 versus BCL-XL dependence and sensitivity to ABT-199
TN Chonghaile, JE Roderick, C Glenfield, J Ryan, SE Sallan, ...
Cancer discovery 4 (9), 1074-1087, 2014
1942014
Phenothiazines induce PP2A-mediated apoptosis in T cell acute lymphoblastic leukemia
A Gutierrez, L Pan, RWJ Groen, F Baleydier, A Kentsis, J Marineau, ...
The Journal of clinical investigation 124 (2), 644-655, 2014
1842014
The BCL11B tumor suppressor is mutated across the major molecular subtypes of T-cell acute lymphoblastic leukemia
A Gutierrez, A Kentsis, T Sanda, L Holmfeldt, SC Chen, J Zhang, ...
Blood, The Journal of the American Society of Hematology 118 (15), 4169-4173, 2011
1782011
T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation
H Feng, DL Stachura, RM White, A Gutierrez, L Zhang, T Sanda, CA Jette, ...
Cancer cell 18 (4), 353-366, 2010
1602010
c-Myc inhibition prevents leukemia initiation in mice and impairs the growth of relapsed and induction failure pediatric T-ALL cells
JE Roderick, J Tesell, LD Shultz, MA Brehm, DL Greiner, MH Harris, ...
Blood, The Journal of the American Society of Hematology 123 (7), 1040-1050, 2014
1462014
Inactivation of ribosomal protein L22 promotes transformation by induction of the stemness factor, Lin28B
S Rao, SY Lee, A Gutierrez, J Perrigoue, RJ Thapa, Z Tu, JR Jeffers, ...
Blood, The Journal of the American Society of Hematology 120 (18), 3764-3773, 2012
1382012
Heat‐shock induction of T‐cell lymphoma/leukaemia in conditional Cre/lox‐regulated transgenic zebrafish
H Feng, DM Langenau, JA Madge, A Quinkertz, A Gutierrez, DS Neuberg, ...
British journal of haematology 138 (2), 169-175, 2007
1342007
Inactivation of LEF1 in T-cell acute lymphoblastic leukemia
A Gutierrez, T Sanda, W Ma, J Zhang, R Grebliunaite, S Dahlberg, ...
Blood, The Journal of the American Society of Hematology 115 (14), 2845-2851, 2010
1332010
NOTCH and PI3K-AKT pathways intertwined
A Gutierrez, AT Look
Cancer cell 12 (5), 411-413, 2007
1312007
TYK2–STAT1–BCL2 pathway dependence in T-cell acute lymphoblastic leukemia
T Sanda, JW Tyner, A Gutierrez, VN Ngo, J Glover, BH Chang, A Yost, ...
Cancer discovery 3 (5), 564-577, 2013
1252013
The TAL1 complex targets the FBXW7 tumor suppressor by activating miR-223 in human T cell acute lymphoblastic leukemia
MR Mansour, T Sanda, LN Lawton, X Li, T Kreslavsky, CD Novina, ...
Journal of Experimental Medicine 210 (8), 1545-1557, 2013
1242013
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