| Inhibitors of interleukin-1β converting enzyme GW Bemis, JMC Golec, DJ Lauffer, MD Mullican, MA Murcko, ... US Patent 5,847,135, 1998 | 226* | 1998 |
| Azo amino acids derivatives D Lauffer, M Mullican US Patent 6,528,533, 2003 | 185* | 2003 |
| Inhibitors of interleukin-1β converting enzyme GW Bemis, JMC Golec, DJ Lauffer, MD Mullican, MA Murcko US Patent 5,756,466, 1998 | 133 | 1998 |
| Inhibitors of interleukin-1β converting enzyme MJ Batchelor, D Bebbington, GW Bemis, WH Fridman, RJ Gillespie, ... US Patent 5,874,424, 1999 | 114 | 1999 |
| Inhibitors of interleukin-1β converting enzyme JMC Golec, DJ Lauffer, DJ Livingston, MD Mullican, PL Nyce, ... US Patent 6,350,741, 2002 | 96 | 2002 |
| Compositions useful as inhibitors of GSK-3 J Cao, D Choquette, R Davies, C Forster, D Lauffer, A Pierce, ... US Patent App. 10/125,885, 2003 | 93 | 2003 |
| Compositions useful as inhibitors of protein kinases A Aronov, DJ Lauffer, P Li, RC Tomlinson US Patent 7,446,199, 2008 | 76 | 2008 |
| 3-Aryl-4-(arylhydrazono)-1H-pyrazol-5-ones: Highly ligand efficient and potent inhibitors of GSK3β M Arnost, A Pierce, E ter Haar, D Lauffer, J Madden, K Tanner, J Green Bioorganic & medicinal chemistry letters 20 (5), 1661-1664, 2010 | 74 | 2010 |
| Inhibitors of interleukin-1β converting enzyme GW Bemis, JMC Golec, DJ Lauffer, MD Mullican, MA Murcko, ... US Patent 5,973,111, 1999 | 71 | 1999 |
| Second-generation antibacterial benzimidazole ureas: discovery of a preclinical candidate with reduced metabolic liability AL Grillot, AL Tiran, D Shannon, E Krueger, Y Liao, H O’Dowd, Q Tang, ... Journal of Medicinal Chemistry 57 (21), 8792-8816, 2014 | 70 | 2014 |
| c-MET protein kinase inhibitors DJ Lauffer, RJ Davies, D Stamos, A Aronov, DD Deininger, R Grey Jr, ... US Patent 7,872,031, 2011 | 70 | 2011 |
| A practical synthesis of (S) 3-tert-butoxycarbonylamino-2-oxo-2, 3, 4, 5-tetrahydro-1, 5-benzodiazepine-1-acetic acid methyl ester as a conformationally restricted dipeptido … DJ Lauffer, MD Mullican Bioorganic & medicinal chemistry letters 12 (8), 1225-1227, 2002 | 64 | 2002 |
| Azaindoles useful as inhibitors of JAK and other protein kinases F Salituro, L Farmer, R Bethiel, E Harrington, J Green, J Come, D Lauffer, ... US Patent 7,507,826, 2009 | 57 | 2009 |
| Inhibitors of interleukin-1β converting enzyme GW Bemis, JMC Golec, DJ Lauffer, MD Mullican, MA Murcko, ... US Patent 6,420,522, 2002 | 56 | 2002 |
| The synthesis and evaluation of peptidyl aspartyl aldehydes as inhibitors of ice. MD Mullican, DJ Lauffer, RJ Gillespie, SS Matharu, D Kay, GM Porritt, ... Bioorganic & Medicinal Chemistry Letters 4 (19), 2359-2364, 1994 | 52 | 1994 |
| Dna-pk inhibitors PS Charifson, KM Cottrell, H Deng, JP Duffy, H Gao, S Giroux, J Green, ... US Patent 9,376,448, 2016 | 48 | 2016 |
| Pyrrolo [2, 3-D] pyrimidines as inhibitors of Janus kinases F Salituro, L Farmer, T Wang, J Wang, R Bethiel, M Wannamaker, ... US Patent 8,580,802, 2013 | 46 | 2013 |
| Inhibitors of interleukin-1β converting enzyme GW Bemis, JMC Golec, DJ Lauffer, MD Mullican, MA Murcko, ... US Patent 7,288,624, 2007 | 43 | 2007 |
| Design and Synthesis of m1-Selective Muscarinic Agonists: (R)-(-)-(Z)-1-Azabicyclo[2.2.1]heptan-3-one, O-(3-(3'-Methoxyphenyl)-2-propynyl)- oxime Maleate (CI … H Tecle, SD Barrett, DJ Lauffer, C Augelli-Szafran, MR Brann, ... Journal of Medicinal Chemistry 41 (14), 2524-2536, 1998 | 40 | 1998 |
| Inhibitors of interleukin-1 β converting enzyme GW Bemis, JMC Golec, DJ Lauffer, MD Mullican, MA Murcko US Patent 6,025,147, 2000 | 37 | 2000 |
