| Active targeting of gold nanoparticles as cancer therapeutics ZR Goddard, MJ Marín, DA Russell, M Searcey Chemical Society Reviews 49 (23), 8774-8789, 2020 | 179 | 2020 |
| Design, synthesis, and evaluation of an α-helix mimetic library targeting protein− protein interactions A Shaginian, LR Whitby, S Hong, I Hwang, B Farooqi, M Searcey, J Chen, ... Journal of the American Chemical Society 131 (15), 5564-5572, 2009 | 167 | 2009 |
| Anti-inflammatory effect of a cell-penetrating peptide targeting the Nrf2/Keap1 interaction R Steel, J Cowan, E Payerne, MA O'Connell, M Searcey ACS medicinal chemistry letters 3 (5), 407-410, 2012 | 133 | 2012 |
| Bisintercalator natural products with potential therapeutic applications: isolation, structure determination, synthetic and biological studies S Dawson, JP Malkinson, D Paumier, M Searcey Natural product reports 24 (1), 109-126, 2007 | 119 | 2007 |
| Synthesis of CC-1065 and duocarmycin analogs via intramolecular aryl radical cyclization of a tethered vinyl chloride DL Boger, CW Boyce, RM Garbaccio, M Searcey Tetrahedron letters 39 (16), 2227-2230, 1998 | 65 | 1998 |
| Cytotoxicity of Pyrazine-Based Cyclometalated (C^Npz^C)Au(III) Carbene Complexes: Impact of the Nature of the Ancillary Ligand on the Biological Properties B Bertrand, J Fernandez-Cestau, J Angulo, MMD Cominetti, ZAE Waller, ... Inorganic Chemistry 56 (10), 5728-5740, 2017 | 63 | 2017 |
| Chemical and biological explorations of the family of CC-1065 and the duocarmycin natural products N Ghosh, HM Sheldrake, M Searcey, K Pors Current topics in medicinal chemistry 9 (16), 1494-1524, 2009 | 62 | 2009 |
| Ligand Bridging of the DNA Holliday Junction: Molecular Recognition of a Stacked‐X Four‐Way Junction by a Small Molecule AL Brogden, NH Hopcroft, M Searcey, CJ Cardin Angewandte Chemie International Edition 46 (21), 3850-3854, 2007 | 60 | 2007 |
| Synthesis of distamycin A polyamides targeting G-quadruplex DNA MJB Moore, F Cuenca, M Searcey, S Neidle Organic & Biomolecular Chemistry 4 (18), 3479-3488, 2006 | 59 | 2006 |
| Duocarmycins-natures prodrugs? M Searcey Current pharmaceutical design 8 (15), 1375-1389, 2002 | 58 | 2002 |
| Synthesis, DNA-cleaving properties and cytotoxicity of intercalating chelidamic acid derivatives. M Searcey, S McClean, B Madden, AT McGown, LP Wakelin Anti-cancer drug design 13 (8), 837-855, 1998 | 57 | 1998 |
| A polyclonal antibody preparation with Michaelian catalytic properties G Gallacher, CS Jackson, M Searcey, GT Badman, R Goel, CM Topham, ... Biochemical Journal 279 (3), 871-881, 1991 | 56 | 1991 |
| The isolation, total synthesis and structure elucidation of chlorofusin, a natural product inhibitor of the p53–MDM2 protein–protein interaction RC Clark, SY Lee, M Searcey, DL Boger Natural product reports 26 (4), 465-477, 2009 | 54 | 2009 |
| Critical role of the linking amide in CC-1065 and the duocarmycins: implications on the source of DNA alkylation catalysis DL Boger, A Santillán, M Searcey, Q Jin Journal of the American Chemical Society 120 (45), 11554-11557, 1998 | 54 | 1998 |
| Antitumor activity of a duocarmycin analogue rationalized to be metabolically activated by cytochrome P450 1A1 in human transitional cell carcinoma of the bladder M Sutherland, JH Gill, PM Loadman, JP Laye, HM Sheldrake, ... Molecular cancer therapeutics 12 (1), 27-37, 2013 | 53 | 2013 |
| Total synthesis and comparative evaluation of luzopeptin A− C and quinoxapeptin A− C DL Boger, MW Ledeboer, M Kume, M Searcey, Q Jin Journal of the American Chemical Society 121 (49), 11375-11383, 1999 | 53 | 1999 |
| A convenient access to benzo-substituted phthalazines as potential precursors to DNA intercalators PG Tsoungas, M Searcey Tetrahedron Letters 42 (37), 6589-6592, 2001 | 52 | 2001 |
| Polyclonal antibody-catalysed amide hydrolysis G Gallacher, M Searcey, CS Jackson, K Brocklehurst Biochemical Journal 284 (3), 675-680, 1992 | 52 | 1992 |
| Synthesis of DNA-directed pyrrolidinyl and piperidinyl confined alkylating chloroalkylaminoanthraquinones: potential for development of tumor-selective N-oxides K Pors, SD Shnyder, PH Teesdale-Spittle, JA Hartley, M Zloh, M Searcey, ... Journal of medicinal chemistry 49 (24), 7013-7023, 2006 | 51 | 2006 |
| X-ray crystallographic study of DNA duplex cross-linking: simultaneous binding to two d (CGTACG) 2 molecules by a bis (9-aminoacridine-4-carboxamide) derivative NH Hopcroft, AL Brogden, M Searcey, CJ Cardin Nucleic acids research 34 (22), 6663-6672, 2006 | 48 | 2006 |
Laurence H PattersonProfessor Emeritus, Institute of Cancer Therapeutics, University of Bradfordכתובת אימייל מאומתת בדומיין bradford.ac.uk
