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Girish C. Melkani, MS, PhD, Associate Professor of Pathology
Girish C. Melkani, MS, PhD, Associate Professor of Pathology
UAB, Heersink School of Medicine
Verified email at uab.edu - Homepage
Title
Cited by
Cited by
Year
Time-restricted eating to prevent and manage chronic metabolic diseases
A Chaix, ENC Manoogian, GC Melkani, S Panda
Annual review of nutrition 39 (1), 291-315, 2019
3922019
Time-restricted feeding attenuates age-related cardiac decline in Drosophila
S Gill, HD Le, GC Melkani, S Panda
Science 347 (6227), 1265-1269, 2015
2812015
Time‐restricted feeding for prevention and treatment of cardiometabolic disorders
GC Melkani, S Panda
The Journal of physiology 595 (12), 3691-3700, 2017
1852017
Time-restricted feeding restores muscle function in Drosophila models of obesity and circadian-rhythm disruption
JE Villanueva, C Livelo, AS Trujillo, S Chandran, B Woodworth, ...
Nature communications 10 (1), 2700, 2019
1332019
Huntington's Disease Induced Cardiac Amyloidosis Is Reversed by Modulating Protein Folding and Oxidative Stress Pathways in the Drosophila Heart
GC Melkani, AS Trujillo, R Ramos, R Bodmer, SI Bernstein, K Ocorr
PLoS genetics 9 (12), e1004024, 2013
962013
Using Drosophila as an integrated model to study mild repetitive traumatic brain injury
A Barekat, A Gonzalez, RE Mauntz, RW Kotzebue, B Molina, ...
Scientific reports 6 (1), 25252, 2016
862016
The UNC-45 myosin chaperone: from worms to flies to vertebrates
CF Lee, GC Melkani, SI Bernstein
International review of cell and molecular biology 313, 103-144, 2014
692014
The UNC-45 Chaperone Is Critical for Establishing Myosin-Based Myofibrillar Organization and Cardiac Contractility in the Drosophila Heart Model
GC Melkani, R Bodmer, K Ocorr, SI Bernstein
PloS one 6 (7), e22579, 2011
682011
αB-crystallin maintains skeletal muscle myosin enzymatic activity and prevents its aggregation under heat-shock stress
GC Melkani, A Cammarato, SI Bernstein
Journal of molecular biology 358 (3), 635-645, 2006
662006
Drosophila UNC-45 accumulates in embryonic blastoderm and in muscles, and is essential for muscle myosin stability
CF Lee, GC Melkani, Q Yu, JA Suggs, WA Kronert, Y Suzuki, L Hipolito, ...
Journal of cell science 124 (5), 699-705, 2011
462011
Increasing autophagy and blocking Nrf2 suppress laminopathy‐induced age‐dependent cardiac dysfunction and shortened lifespan
S Bhide, AS Trujillo, MT O'Connor, GH Young, DE Cryderman, ...
Aging cell 17 (3), e12747, 2018
452018
When a calorie is not just a calorie: Diet quality and timing as mediators of metabolism and healthy aging
MM Mihaylova, A Chaix, M Delibegovic, JJ Ramsey, J Bass, G Melkani, ...
Cell metabolism 35 (7), 1114-1131, 2023
432023
Drosophila UNC-45 prevents heat-induced aggregation of skeletal muscle myosin and facilitates refolding of citrate synthase
GC Melkani, CF Lee, A Cammarato, SI Bernstein
Biochemical and biophysical research communications 396 (2), 317-322, 2010
402010
Prolonged cross-bridge binding triggers muscle dysfunction in a Drosophila model of myosin-based hypertrophic cardiomyopathy
WA Kronert, KM Bell, MC Viswanathan, GC Melkani, AS Trujillo, A Huang, ...
Elife 7, e38064, 2018
362018
The relay/converter interface influences hydrolysis of ATP by skeletal muscle myosin II
MJ Bloemink, GC Melkani, SI Bernstein, MA Geeves
Journal of Biological Chemistry 291 (4), 1763-1773, 2016
302016
TRiC/CCT chaperonins are essential for maintaining myofibril organization, cardiac physiological rhythm, and lifespan
GC Melkani, S Bhide, A Han, J Vyas, C Livelo, R Bodmer, SI Bernstein
FEBS letters 591 (21), 3447-3458, 2017
272017
The ATPase activity of GroEL is supported at high temperatures by divalent cations that stabilize its structure
GC Melkani, G Zardeneta, JA Mendoza
Biometals 16, 479-484, 2003
242003
Alternative exon 9-encoded relay domains affect more than one communication pathway in the Drosophila myosin head
MJ Bloemink, CM Dambacher, AF Knowles, GC Melkani, MA Geeves, ...
Journal of molecular biology 389 (4), 707-721, 2009
222009
Huntington’s disease-induced cardiac disorders affect multiple cellular pathways
GC Melkani
Reactive oxygen species (Apex, NC) 2 (5), 325, 2016
212016
Expression of the inclusion body myopathy 3 mutation in Drosophila depresses myosin function and stability and recapitulates muscle inclusions and weakness
Y Wang, GC Melkani, JA Suggs, A Melkani, WA Kronert, A Cammarato, ...
Molecular biology of the cell 23 (11), 2057-2065, 2012
212012
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