Kevin Janes
Kevin Janes
John Marshall Money Professor of Biomedical Engineering, University of Virginia
Verified email at - Homepage
Cited by
Cited by
Chitosan-DNA nanoparticles as gene carriers: synthesis, characterization and transfection efficiency
HQ Mao, K Roy, VL Troung-Le, KA Janes, KY Lin, Y Wang, JT August, ...
Journal of controlled release 70 (3), 399-421, 2001
Polysaccharide colloidal particles as delivery systems for macromolecules
KA Janes, P Calvo, MJ Alonso
Advanced drug delivery reviews 47 (1), 83-97, 2001
Chitosan nanoparticles as delivery systems for doxorubicin
KA Janes, MP Fresneau, A Marazuela, A Fabra, MJ Alonso
Journal of controlled Release 73 (2-3), 255-267, 2001
A systems model of signaling identifies a molecular basis set for cytokine-induced apoptosis
KA Janes, JG Albeck, S Gaudet, PK Sorger, DA Lauffenburger, MB Yaffe
Science 310 (5754), 1646-1653, 2005
Low molecular weight chitosan nanoparticles as new carriers for nasal vaccine delivery in mice
A Vila, A Sánchez, K Janes, I Behrens, T Kissel, JLV Jato, MJ Alonso
European Journal of pharmaceutics and biopharmaceutics 57 (1), 123-131, 2004
Data-driven modelling of signal-transduction networks
KA Janes, MB Yaffe
Nature reviews Molecular cell biology 7 (11), 820-828, 2006
The response of human epithelial cells to TNF involves an inducible autocrine cascade
KA Janes, S Gaudet, JG Albeck, UB Nielsen, DA Lauffenburger, ...
Cell 124 (6), 1225-1239, 2006
Depolymerized chitosan nanoparticles for protein delivery: preparation and characterization
KA Janes, MJ Alonso
Journal of applied polymer science 88 (12), 2769-2776, 2003
A multiplexed homogeneous fluorescence-based assay for protein kinase activity in cell lysates
MD Shults, KA Janes, DA Lauffenburger, B Imperiali
Nature methods 2 (4), 277-284, 2005
An analysis of critical factors for quantitative immunoblotting
KA Janes
Science signaling 8 (371), rs2-rs2, 2015
Common effector processing mediates cell-specific responses to stimuli
K Miller-Jensen, KA Janes, JS Brugge, DA Lauffenburger
Nature 448 (7153), 604-608, 2007
A Compendium of Signals and Responses Triggered by Prodeath and Prosurvival Cytokines
S Gaudet, KA Janes, JG Albeck, EA Pace, DA Lauffenburger, PK Sorger
Molecular & Cellular Proteomics 4 (10), 1569-1590, 2005
Applying computational modeling to drug discovery and development
N Kumar, BS Hendriks, KA Janes, D de Graaf, DA Lauffenburger
Drug discovery today 11 (17-18), 806-811, 2006
A biological approach to computational models of proteomic networks
KA Janes, DA Lauffenburger
Current opinion in chemical biology 10 (1), 73-80, 2006
Cue-signal-response analysis of TNF-induced apoptosis by partial least squares regression of dynamic multivariate data
KA Janes, JR Kelly, S Gaudet, JG Albeck, PK Sorger, DA Lauffenburger
Journal of Computational Biology 11 (4), 544-561, 2004
Intersection of FOXO-and RUNX1-mediated gene expression programs in single breast epithelial cells during morphogenesis and tumor progression
L Wang, JS Brugge, KA Janes
Proceedings of the National Academy of Sciences 108 (40), E803-E812, 2011
Identifying single-cell molecular programs by stochastic profiling
KA Janes, CC Wang, KJ Holmberg, K Cabral, JS Brugge
Nature methods 7 (4), 311-317, 2010
A high-throughput quantitative multiplex kinase assay for monitoring information flow in signaling networks: application to sepsis-apoptosis
KA Janes, JG Albeck, LX Peng, PK Sorger, DA Lauffenburger, MB Yaffe
Molecular & Cellular Proteomics 2 (7), 463-473, 2003
Cytokine-induced signaling networks prioritize dynamic range over signal strength
KA Janes, HC Reinhardt, MB Yaffe
Cell 135 (2), 343-354, 2008
Astrocytic trans-differentiation completes a multicellular paracrine feedback loop required for medulloblastoma tumor growth
M Yao, PB Ventura, Y Jiang, FJ Rodriguez, L Wang, JSA Perry, Y Yang, ...
Cell 180 (3), 502-520. e19, 2020
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