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Thomas W. Dubensky, Jr.
Thomas W. Dubensky, Jr.
Tempest Therapeutics
Verified email at tempesttx.com - Homepage
Title
Cited by
Cited by
Year
Direct activation of STING in the tumor microenvironment leads to potent and systemic tumor regression and immunity
L Corrales, LH Glickman, SM McWhirter, DB Kanne, KE Sivick, ...
Cell reports 11 (7), 1018-1030, 2015
12662015
STING agonist formulated cancer vaccines can cure established tumors resistant to PD-1 blockade
J Fu, DB Kanne, M Leong, LH Glickman, SM McWhirter, E Lemmens, ...
Science translational medicine 7 (283), 283ra52-283ra52, 2015
7192015
Safety and survival with GVAX pancreas prime and Listeria monocytogenes–expressing mesothelin (CRS-207) boost vaccines for metastatic pancreatic cancer
DT Le, A Wang-Gillam, V Picozzi, TF Greten, T Crocenzi, G Springett, ...
Journal of clinical Oncology 33 (12), 1325, 2015
6362015
Interferon-producing killer dendritic cells provide a link between innate and adaptive immunity
CW Chan, E Crafton, HN Fan, J Flook, K Yoshimura, M Skarica, ...
Nature medicine 12 (2), 207-213, 2006
5402006
The host STING pathway at the interface of cancer and immunity
L Corrales, SM McWhirter, TW Dubensky, TF Gajewski
The Journal of clinical investigation 126 (7), 2404-2411, 2016
3982016
A live-attenuated Listeria vaccine (ANZ-100) and a live-attenuated Listeria vaccine expressing mesothelin (CRS-207) for advanced cancers: phase I studies of safety and immune …
DT Le, DG Brockstedt, R Nir-Paz, J Hampl, S Mathur, J Nemunaitis, ...
Clinical cancer research 18 (3), 858-868, 2012
3732012
Alphavirus-based DNA vaccine breaks immunological tolerance by activating innate antiviral pathways
WW Leitner, LN Hwang, MJ Deveer, A Zhou, RH Silverman, BRG Williams, ...
Nature medicine 9 (1), 33-39, 2003
3542003
Listeria-based cancer vaccines that segregate immunogenicity from toxicity
DG Brockstedt, MA Giedlin, ML Leong, KS Bahjat, Y Gao, W Luckett, ...
Proceedings of the National Academy of Sciences 101 (38), 13832-13837, 2004
3522004
Adjuvants for cancer vaccines
TW Dubensky Jr, SG Reed
Seminars in immunology 22 (3), 155-161, 2010
3332010
Magnitude of therapeutic STING activation determines CD8+ T cell-mediated anti-tumor immunity
KE Sivick, AL Desbien, LH Glickman, GL Reiner, L Corrales, NH Surh, ...
Cell reports 25 (11), 3074-3085. e5, 2018
3042018
Eukaryotic layered vector initiation systems
TW Dubensky Jr, JM Polo, DJ Jolly, DA Driver
US Patent 5,814,482, 1998
3021998
Sindbis virus DNA-based expression vectors: utility for in vitro and in vivo gene transfer
TW Dubensky Jr, DA Driver, JM Polo, BA Belli, EM Latham, CE Ibanez, ...
Journal of virology 70 (1), 508-519, 1996
2701996
DNA immunization against herpes simplex virus: enhanced efficacy using a Sindbis virus-based vector
MJ Hariharan, DA Driver, K Townsend, D Brumm, JM Polo, BA Belli, ...
Journal of virology 72 (2), 950-958, 1998
2681998
VSV-G pseudotyped lentiviral vector particles produced in human cells are inactivated by human serum
NJ DePolo, JD Reed, PL Sheridan, K Townsend, SL Sauter, DJ Jolly, ...
Molecular Therapy 2 (3), 218-222, 2000
2592000
Role of PD-1 and its ligand, B7-H1, in early fate decisions of CD8 T cells
MV Goldberg, CH Maris, EL Hipkiss, AS Flies, L Zhen, RM Tuder, ...
Blood, The Journal of the American Society of Hematology 110 (1), 186-192, 2007
2422007
Enhancement of tumor-specific immune response with plasmid DNA replicon vectors
WW Leitner, H Ying, DA Driver, TW Dubensky, NP Restifo
Cancer research 60 (1), 51-55, 2000
2422000
Radiotherapy combined with novel STING-targeting oligonucleotides results in regression of established tumors
JR Baird, D Friedman, B Cottam, TW Dubensky Jr, DB Kanne, S Bambina, ...
Cancer research 76 (1), 50-61, 2016
2262016
Feline immunodeficiency virus vectors persistently transduce nondividing airway epithelia and correct the cystic fibrosis defect
G Wang, V Slepushkin, J Zabner, S Keshavjee, JC Johnston, SL Sauter, ...
The Journal of clinical investigation 104 (11), R55-R62, 1999
2201999
An alphavirus replicon particle chimera derived from venezuelan equine encephalitis and sindbis viruses is a potent gene-based vaccine delivery vector
S Perri, CE Greer, K Thudium, B Doe, H Legg, H Liu, RE Romero, Z Tang, ...
Journal of virology 77 (19), 10394-10403, 2003
2172003
Alphavirus structural protein expression cassettes
TW Dubensky Jr, JM Polo, CE Ibanez, SMW Chang, DJ Jolly, DA Driver
US Patent 5,789,245, 1998
2051998
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