| Microglia clear neuron-released α-synuclein via selective autophagy and prevent neurodegeneration I Choi, Y Zhang, SP Seegobin, M Pruvost, Q Wang, K Purtell, B Zhang, ... Nature communications 11 (1), 1386, 2020 | 334 | 2020 |
| LRRK2 G2019S mutation attenuates microglial motility by inhibiting focal adhesion kinase I Choi, B Kim, JW Byun, SH Baik, YH Huh, JH Kim, I Mook-Jung, WK Song, ... Nature Communications 6 (1), 8255, 2015 | 99 | 2015 |
| PINK1 deficiency attenuates astrocyte proliferation through mitochondrial dysfunction, reduced AKT and increased p38 MAPK activation, and downregulation of EGFR I Choi, J Kim, HK Jeong, B Kim, I Jou, SM Park, L Chen, UJ Kang, ... Glia 61 (5), 800-812, 2013 | 96 | 2013 |
| The landscape of multiscale transcriptomic networks and key regulators in Parkinson’s disease Q Wang, Y Zhang, M Wang, WM Song, Q Shen, A McKenzie, I Choi, ... Nature communications 10 (1), 5234, 2019 | 95 | 2019 |
| PINK1 deficiency enhances inflammatory cytokine release from acutely prepared brain slices J Kim, JW Byun, I Choi, B Kim, HK Jeong, I Jou, E Joe Experimental neurobiology 22 (1), 38, 2013 | 74 | 2013 |
| PINK1 expression increases during brain development and stem cell differentiation, and affects the development of GFAP-positive astrocytes I Choi, DJ Choi, H Yang, JH Woo, MY Chang, JY Kim, W Sun, SM Park, ... Molecular brain 9, 1-12, 2016 | 58 | 2016 |
| Autophagy protein NRBF2 has reduced expression in Alzheimer’s brains and modulates memory and amyloid-beta homeostasis in mice V Lachance, Q Wang, E Sweet, I Choi, CZ Cai, XX Zhuang, Y Zhang, ... Molecular neurodegeneration 14, 1-13, 2019 | 56 | 2019 |
| Interplay between leucine-rich repeat kinase 2 (LRRK2) and p62/SQSTM-1 in selective autophagy S Park, S Han, I Choi, B Kim, SP Park, EH Joe, YH Suh PloS one 11 (9), e0163029, 2016 | 51 | 2016 |
| PINK1 positively regulates HDAC3 to suppress dopaminergic neuronal cell death HK Choi, Y Choi, HB Kang, E Lim, SY Park, HS Lee, JM Park, J Moon, ... Human Molecular Genetics 24 (4), 1127-1141, 2015 | 48 | 2015 |
| Progress in LRRK2-associated Parkinson’s disease animal models SP Seegobin, GR Heaton, D Liang, I Choi, M Blanca Ramirez, B Tang, ... Frontiers in Neuroscience 14, 539964, 2020 | 37 | 2020 |
| Synj1 haploinsufficiency causes dopamine neuron vulnerability and alpha-synuclein accumulation in mice PY Pan, P Sheehan, Q Wang, X Zhu, Y Zhang, I Choi, X Li, J Saenz, J Zhu, ... Human molecular genetics 29 (14), 2300-2312, 2020 | 34 | 2020 |
| PINK1 deficiency decreases expression levels of mir-326, mir-330, and mir-3099 during brain development and neural stem cell differentiation I Choi, JH Woo, I Jou, E Joe Experimental neurobiology 25 (1), 14, 2016 | 34 | 2016 |
| Astrogliosis is a possible player in preventing delayed neuronal death HK Jeong, KM Ji, KJ Min, I Choi, DJ Choi, I Jou, EH Joe Molecules and cells 37 (4), 345-355, 2014 | 32 | 2014 |
| Selective autophagy of AKAP11 activates cAMP/PKA to fuel mitochondrial metabolism and tumor cell growth Z Deng, X Li, M Blanca Ramirez, K Purtell, I Choi, JH Lu, Q Yu, Z Yue Proceedings of the National Academy of Sciences 118 (14), e2020215118, 2021 | 30 | 2021 |
| Autophagy enables microglia to engage amyloid plaques and prevents microglial senescence I Choi, M Wang, S Yoo, P Xu, SP Seegobin, X Li, X Han, Q Wang, J Peng, ... Nature cell biology 25 (7), 963-974, 2023 | 27 | 2023 |
| Synucleinphagy: A microglial “community cleanup program” for neuroprotection I Choi, SP Seegobin, D Liang, Z Yue Autophagy 16 (9), 1718-1720, 2020 | 19 | 2020 |
| Regulation of α-synuclein homeostasis and inflammasome activation by microglial autophagy I Choi, GR Heaton, YK Lee, Z Yue Science advances 8 (43), eabn1298, 2022 | 15 | 2022 |
| Single-cell transcriptomic atlas of the human substantia nigra in Parkinson’s disease Q Wang, M Wang, I Choi, L Ho, K Farrell, KG Beaumont, R Sebra, ... Biorxiv, 2022.03. 25.485846, 2022 | 14 | 2022 |
| Region-specific astrogliosis: differential vessel formation contributes to different patterns of astrogliosis in the cortex and striatum H Yang, J An, I Choi, K Lee, SM Park, I Jou, EH Joe Molecular Brain 13, 1-15, 2020 | 6 | 2020 |
| LRRK2 inhibits FAK activity by promoting FERM-mediated autoinhibition of FAK and recruiting the tyrosine phosphatase, SHP-2 I Choi, J Byun, SM Park, I Jou, EH Joe Experimental Neurobiology 25 (5), 269, 2016 | 4 | 2016 |
