Dierssen Mara
Dierssen Mara
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Cognitive deficits and associated neurological complications in individuals with Down's syndrome
IT Lott, M Dierssen
The Lancet Neurology 9 (6), 623-633, 2010
Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down’s syndrome
X Altafaj, M Dierssen, C Baamonde, E Martí, J Visa, J Guimerà, M Oset, ...
Human molecular genetics 10 (18), 1915-1923, 2001
Dyrk1A Haploinsufficiency Affects Viability and Causes Developmental Delay and Abnormal Brain Morphology in Mice
V Fotaki, M Dierssen, S Alcántara, S Martínez, E Martí, C Casas, J Visa, ...
Molecular and cellular biology 22 (18), 6636-6647, 2002
Down syndrome: the brain in trisomic mode
M Dierssen
Nature Reviews Neuroscience 13 (12), 844-858, 2012
Epigallocatechin‐3‐gallate, a DYRK1A inhibitor, rescues cognitive deficits in D own syndrome mouse models and in humans
R De la Torre, S De Sola, M Pons, A Duchon, MM de Lagran, M Farré, ...
Molecular nutrition & food research 58 (2), 278-288, 2014
Erbb4 deletion from fast-spiking interneurons causes schizophrenia-like phenotypes
I Del Pino, C García-Frigola, N Dehorter, JR Brotons-Mas, ...
Neuron 79 (6), 1152-1168, 2013
A behavioral assessment of Ts65Dn mice: a putative Down syndrome model
RM Escorihuela, A Fernández-Teruel, IF Vallina, C Baamonde, ...
Neuroscience letters 199 (2), 143-146, 1995
Safety and efficacy of cognitive training plus epigallocatechin-3-gallate in young adults with Down's syndrome (TESDAD): a double-blind, randomised, placebo-controlled, phase 2 …
R de la Torre, S de Sola, G Hernandez, M Farré, J Pujol, J Rodriguez, ...
The Lancet Neurology 15 (8), 801-810, 2016
Potential role of olive oil phenolic compounds in the prevention of neurodegenerative diseases
J Rodríguez-Morató, L Xicota, M Fitó, M Farré, M Dierssen, R De la Torre
Molecules 20 (3), 4655-4680, 2015
Targeting the endocannabinoid system in the treatment of fragile X syndrome
A Busquets-Garcia, M Gomis-González, T Guegan, C Agustín-Pavón, ...
Nature medicine 19 (5), 603-607, 2013
Dendritic pathology in mental retardation: from molecular genetics to neurobiology
M Dierssen, GJA Ramakers
Genes, Brain and Behavior 5, 48-60, 2006
Synthetic zinc finger repressors reduce mutant huntingtin expression in the brain of R6/2 mice
M Garriga-Canut, C Agustín-Pavón, F Herrmann, A Sánchez, M Dierssen, ...
Proceedings of the National Academy of Sciences 109 (45), E3136-E3145, 2012
Differential effects of environmental enrichment on behavior and learning of male and female Ts65Dn mice, a model for Down syndrome
C Martı́nez-Cué, C Baamonde, M Lumbreras, J Paz, MT Davisson, ...
Behavioural brain research 134 (1-2), 185-200, 2002
Hippocampal volume and neuronal number in Ts65Dn mice: a murine model of Down syndrome
AM Insausti, M Megıas, D Crespo, LM Cruz-Orive, M Dierssen, TF Vallina, ...
Neuroscience letters 253 (3), 175-178, 1998
Impaired short-and long-term memory in Ts65Dn mice, a model for Down syndrome
RM Escorihuela, IF Vallina, C Martı́nez-Cué, C Baamonde, M Dierssen, ...
Neuroscience letters 247 (2-3), 171-174, 1998
Alterations of neocortical pyramidal cell phenotype in the Ts65Dn mouse model of Down syndrome: effects of environmental enrichment
M Dierssen, R Benavides-Piccione, C Martínez-Cué, X Estivill, J Flórez, ...
Cerebral cortex 13 (7), 758-764, 2003
Constitutive Dyrk1A is abnormally expressed in Alzheimer disease, Down syndrome, Pick disease, and related transgenic models
I Ferrer, M Barrachina, B Puig, MM De Lagrán, E Martí, J Avila, ...
Neurobiology of disease 20 (2), 392-400, 2005
Down syndrome: from understanding the neurobiology to therapy
K Gardiner, Y Herault, IT Lott, SE Antonarakis, RH Reeves, M Dierssen
Journal of Neuroscience 30 (45), 14943-14945, 2010
Aneuploidy: from a physiological mechanism of variance to Down syndrome
M Dierssen, Y Herault, X Estivill
Physiological reviews, 2009
Dyrk1A expression pattern supports specific roles of this kinase in the adult central nervous system
E Martı́, X Altafaj, M Dierssen, S de la Luna, V Fotaki, M Alvarez, ...
Brain research 964 (2), 250-263, 2003
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