Progestogens used in postmenopausal hormone therapy: differences in their pharmacological properties, intracellular actions, and clinical effects FZ Stanczyk, JP Hapgood, S Winer, DR Mishell Jr Endocrine reviews 34 (2), 171-208, 2013 | 454 | 2013 |
A fully dissociated compound of plant origin for inflammatory gene repression K De Bosscher, WV Berghe, IME Beck, W Van Molle, N Hennuyer, ... Proceedings of the National Academy of Sciences 102 (44), 15827-15832, 2005 | 336 | 2005 |
Molecular mechanisms of steroid receptor-mediated actions by synthetic progestins used in HRT and contraception D Africander, N Verhoog, JP Hapgood Steroids 76 (7), 636-652, 2011 | 311 | 2011 |
Two gonadotropin-releasing hormone receptor subtypes with distinct ligand selectivity and differential distribution in brain and pituitary in the goldfish (Carassius auratus) N Illing, BE Troskie, CS Nahorniak, JP Hapgood, RE Peter, RP Millar Proceedings of the National Academy of Sciences 96 (5), 2526-2531, 1999 | 240 | 1999 |
Ligand-selective transactivation and transrepression via the glucocorticoid receptor: role of cofactor interaction K Ronacher, K Hadley, C Avenant, E Stubsrud, SS Simons Jr, A Louw, ... Molecular and cellular endocrinology 299 (2), 219-231, 2009 | 165 | 2009 |
Synthetic progestins used in HRT have different glucocorticoid agonist properties D Koubovec, K Ronacher, E Stubsrud, A Louw, JP Hapgood Molecular and cellular endocrinology 242 (1-2), 23-32, 2005 | 154 | 2005 |
Specific protein-DNA interactions at a xenobiotic-responsive element: copurification of dioxin receptor and DNA-binding activity. J Hapgood, S Cuthill, M Denis, L Poellinger, JA Gustafsson Proceedings of the National Academy of Sciences 86 (1), 60-64, 1989 | 142 | 1989 |
Regulation of expression of mammalian gonadotrophin‐releasing hormone receptor genes JP Hapgood, H Sadie, W Van Biljon, K Ronacher Journal of neuroendocrinology 17 (10), 619-638, 2005 | 126 | 2005 |
Hormonal contraception and HIV-1 acquisition: biological mechanisms JP Hapgood, C Kaushic, Z Hel Endocrine reviews 39 (1), 36-78, 2018 | 123 | 2018 |
Identification of three putative GnRH receptor subtypes in vertebrates B Troskie, N Illing, E Rumbak, YM Sun, J Hapgood, S Sealfon, D Conklin, ... General and comparative endocrinology 112 (3), 296-302, 1998 | 123 | 1998 |
Potency of progestogens used in hormonal therapy: toward understanding differential actions JP Hapgood, D Africander, R Louw, RM Ray, JM Rohwer The Journal of steroid biochemistry and molecular biology 142, 39-47, 2014 | 109 | 2014 |
Complementary deoxyribonucleic acid cloning, gene expression, and ligand selectivity of a novel gonadotropin-releasing hormone receptor expressed in the pituitary and midbrain … BE Troskie, JP Hapgood, RP Millar, N Illing Endocrinology 141 (5), 1764-1771, 2000 | 99 | 2000 |
Abrogation of glucocorticoid receptor dimerization correlates with dissociated glucocorticoid behavior of compound a S Robertson, F Allie-Reid, WV Berghe, K Visser, A Binder, D Africander, ... Journal of Biological Chemistry 285 (11), 8061-8075, 2010 | 98 | 2010 |
A novel human GnRH receptor homolog gene: abundant and wide tissue distribution of the antisense transcript R Millar, D Conklin, C Lofton-Day, E Hutchinson, B Troskie, N Illing, ... Journal of Endocrinology 162 (1), 117-126, 1999 | 92 | 1999 |
A chicken gonadotropin-releasing hormone receptor that confers agonist activity to mammalian antagonists: identification of D-Lys6 in the ligand and extracellular loop two of … YM Sun, CA Flanagan, N Illing, TR Ott, R Sellar, BJ Fromme, J Hapgood, ... Journal of Biological Chemistry 276 (11), 7754-7761, 2001 | 88 | 2001 |
Depot medroxyprogesterone versus norethisterone oenanthate for long-acting progestogenic contraception BH Draper, C Morroni, M Hoffman, J Smit, M Beksinska, J Hapgood, ... The Cochrane database of systematic reviews., CD005214, 2006 | 82* | 2006 |
Comparing the androgenic and estrogenic properties of progestins used in contraception and hormone therapy R Louw-du Toit, MS Perkins, JP Hapgood, D Africander Biochemical and biophysical research communications 491 (1), 140-146, 2017 | 80 | 2017 |
Glucocorticoid-independent modulation of GR activity: Implications for immunotherapy JP Hapgood, C Avenant, JM Moliki Pharmacology & therapeutics 165, 93-113, 2016 | 80 | 2016 |
The injectable-only contraceptive medroxyprogesterone acetate, unlike norethisterone acetate and progesterone, regulates inflammatory genes in endocervical cells via the … Y Govender, C Avenant, NJD Verhoog, RM Ray, NJ Grantham, ... PloS one 9 (5), e96497, 2014 | 80 | 2014 |
Differential regulation of endogenous pro-inflammatory cytokine genes by medroxyprogesterone acetate and norethisterone acetate in cell lines of the female genital tract D Africander, R Louw, N Verhoog, D Noeth, JP Hapgood Contraception 84 (4), 423-435, 2011 | 74 | 2011 |