James C H Hardwick
James C H Hardwick
Leiden University Medical Center, Leiden, The Netherlands
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Cited by
Cited by
Leptin is a growth factor for colonic epithelial cells
JCH Hardwick, GR Van Den Brink, GJ Offerhaus, SJH Van Deventer, ...
Gastroenterology 121 (1), 79-90, 2001
Indian Hedgehog is an antagonist of Wnt signaling in colonic epithelial cell differentiation
GR Van Den Brink, SA Bleuming, JCH Hardwick, BL Schepman, ...
Nature genetics 36 (3), 277-282, 2004
Narrow-band imaging compared with conventional colonoscopy for the detection of dysplasia in patients with longstanding ulcerative colitis
E Dekker, FJC van den Broek, JB Reitsma, JC Hardwick, GJ Offerhaus, ...
Endoscopy 39 (03), 216-221, 2007
Bone morphogenetic protein 2 is expressed by, and acts upon, mature epithelial cells in the colon
JCH Hardwick, GR Van Den Brink, SA Bleuming, I Ballester, ...
Gastroenterology 126 (1), 111-121, 2004
Sonic hedgehog regulates gastric gland morphogenesis in man and mouse
GR Van Den Brink, JCH Hardwick, MP Peppelenbosch, ...
Gastroenterology 121 (2), 317-328, 2001
Endoscopic tri-modal imaging for surveillance in ulcerative colitis: randomised comparison of high-resolution endoscopy and autofluorescence imaging for neoplasia detection …
FJC van den Broek, P Fockens, S van Eeden, JB Reitsma, JCH Hardwick, ...
Gut 57 (8), 1083-1089, 2008
Detection of colorectal polyps in humans using an intravenously administered fluorescent peptide targeted against c-Met
J Burggraaf, IMC Kamerling, PB Gordon, L Schrier, ML De Kam, AJ Kales, ...
Nature medicine 21 (8), 955-961, 2015
One to 2-year surveillance intervals reduce risk of colorectal cancer in families with Lynch syndrome
HFA Vasen, M Abdirahman, R Brohet, AMJ Langers, JH Kleibeuker, ...
Gastroenterology 138 (7), 2300-2306, 2010
ER stress causes rapid loss of intestinal epithelial stemness through activation of the unfolded protein response
J Heijmans, JFL de Jeude, BK Koo, SL Rosekrans, MCB Wielenga, ...
Cell reports 3 (4), 1128-1139, 2013
Bone morphogenetic protein signalling in colorectal cancer
JC Hardwick, LL Kodach, GJ Offerhaus, GR Van Den Brink
Nature Reviews Cancer 8 (10), 806-812, 2008
Sonic hedgehog expression correlates with fundic gland differentiation in the adult gastrointestinal tract
GR van den Brink, JCH Hardwick, C Nielsen, C Xu, FJ Ten Kate, ...
Gut 51 (5), 628-633, 2002
Violacein synergistically increases 5-fluorouracil cytotoxicity, induces apoptosis and inhibits Akt-mediated signal transduction in human colorectal cancer cells
LL Kodach, CL Bos, N Durán, MP Peppelenbosch, CV Ferreira, ...
Carcinogenesis 27 (3), 508-516, 2006
The bone morphogenetic protein pathway is inactivated in the majority of sporadic colorectal cancers
LL Kodach, E Wiercinska, NFCC De Miranda, SA Bleuming, AR Musler, ...
Gastroenterology 134 (5), 1332-1341. e3, 2008
Identification of patients with variants in TPMT and dose reduction reduces hematologic events during thiopurine treatment of inflammatory bowel disease
MJH Coenen, DJ de Jong, CJ van Marrewijk, LJJ Derijks, SH Vermeulen, ...
Gastroenterology 149 (4), 907-917. e7, 2015
Loss of SMAD4 alters BMP signaling to promote colorectal cancer cell metastasis via activation of Rho and ROCK
PW Voorneveld, LL Kodach, RJ Jacobs, N Liv, AC Zonnevylle, ...
Gastroenterology 147 (1), 196-208. e13, 2014
Effect of aspirin on the Wnt/β-catenin pathway is mediated via protein phosphatase 2A
CL Bos, LL Kodach, GR van den Brink, SH Diks, MM van Santen, ...
Oncogene 25 (49), 6447-6456, 2006
Quality of web-based information on inflammatory bowel diseases
S van der Marel, M Duijvestein, JC Hardwick, GR van den Brink, ...
Inflammatory bowel diseases 15 (12), 1891-1896, 2009
Endoglin expression on cancer-associated fibroblasts regulates invasion and stimulates colorectal cancer metastasis
M Paauwe, MJA Schoonderwoerd, RFCP Helderman, TJ Harryvan, ...
Clinical Cancer Research 24 (24), 6331-6344, 2018
Statins augment the chemosensitivity of colorectal cancer cells inducing epigenetic reprogramming and reducing colorectal cancer cell ‘stemness’ via the bone morphogenetic …
LL Kodach, RJ Jacobs, PW Voorneveld, ME Wildenberg, HW Verspaget, ...
Gut 60 (11), 1544-1553, 2011
Blimp1 regulates the transition of neonatal to adult intestinal epithelium
V Muncan, J Heijmans, SD Krasinski, NV Büller, ME Wildenberg, ...
Nature communications 2 (1), 452, 2011
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