| Solution conditions determine the relative importance of nucleation and growth processes in α-synuclein aggregation AK Buell, C Galvagnion, R Gaspar, E Sparr, M Vendruscolo, TPJ Knowles, ... Proceedings of the National Academy of Sciences 111 (21), 7671-7676, 2014 | 675 | 2014 |
| Acceleration of α-synuclein aggregation by exosomes M Grey, CJ Dunning, R Gaspar, C Grey, P Brundin, E Sparr, S Linse Journal of Biological Chemistry 290 (5), 2969-2982, 2015 | 364 | 2015 |
| Islet amyloid polypeptide‐induced membrane leakage involves uptake of lipids by forming amyloid fibers E Sparr, MFM Engel, DV Sakharov, M Sprong, J Jacobs, B de Kruijff, ... FEBS letters 577 (1-2), 117-120, 2004 | 307 | 2004 |
| Chemical properties of lipids strongly affect the kinetics of the membrane-induced aggregation of α-synuclein C Galvagnion, JWP Brown, MM Ouberai, P Flagmeier, M Vendruscolo, ... Proceedings of the National Academy of Sciences 113 (26), 7065-7070, 2016 | 295 | 2016 |
| Cholesterol catalyses Aβ42 aggregation through a heterogeneous nucleation pathway in the presence of lipid membranes J Habchi, S Chia, C Galvagnion, TCT Michaels, MMJ Bellaiche, ... Nature chemistry 10 (6), 673-683, 2018 | 218 | 2018 |
| Secondary nucleation of monomers on fibril surface dominates α-synuclein aggregation and provides autocatalytic amyloid amplification R Gaspar, G Meisl, AK Buell, L Young, CF Kaminski, TPJ Knowles, ... Quarterly reviews of biophysics 50, e6, 2017 | 215 | 2017 |
| Chemical penetration enhancers in stratum corneum—Relation between molecular effects and barrier function QD Pham, S Björklund, J Engblom, D Topgaard, E Sparr Journal of controlled release 232, 175-187, 2016 | 188 | 2016 |
| Self-association of transmembrane α-helices in model membranes: importance of helix orientation and role of hydrophobic mismatch E Sparr, WL Ash, PV Nazarov, DTS Rijkers, MA Hemminga, DP Tieleman, ... Journal of Biological Chemistry 280 (47), 39324-39331, 2005 | 163 | 2005 |
| Membrane interaction of α-synuclein in different aggregation states M Grey, S Linse, H Nilsson, P Brundin, E Sparr Journal of Parkinson's disease 1 (4), 359-371, 2011 | 146 | 2011 |
| Stratum corneum hydration: phase transformations and mobility in stratum corneum, extracted lipids and isolated corneocytes CL Silva, D Topgaard, V Kocherbitov, JJS Sousa, AACC Pais, E Sparr Biochimica et Biophysica Acta (BBA)-Biomembranes 1768 (11), 2647-2659, 2007 | 142 | 2007 |
| Membrane lipid co-aggregation with α-synuclein fibrils E Hellstrand, A Nowacka, D Topgaard, S Linse, E Sparr PloS one 8 (10), e77235, 2013 | 130 | 2013 |
| Skin hydration: interplay between molecular dynamics, structure and water uptake in the stratum corneum EH Mojumdar, QD Pham, D Topgaard, E Sparr Scientific reports 7 (1), 15712, 2017 | 126 | 2017 |
| Glycerol and urea can be used to increase skin permeability in reduced hydration conditions S Björklund, J Engblom, K Thuresson, E Sparr European Journal of Pharmaceutical Sciences 50 (5), 638-645, 2013 | 122 | 2013 |
| Development of supramolecular structure through alkylation of pendant pyridyl functionality EC Constable, CE Housecroft, M Neuburger, D Phillips, PR Raithby, ... Journal of the Chemical Society, Dalton Transactions, 2219-2228, 2000 | 119 | 2000 |
| Ionization Constants pKa of Cardiolipin G Olofsson, E Sparr PloS one 8 (9), e73040, 2013 | 117 | 2013 |
| A water gradient can be used to regulate drug transport across skin S Björklund, J Engblom, K Thuresson, E Sparr Journal of controlled release 143 (2), 191-200, 2010 | 106 | 2010 |
| Responding phospholipid membranes—interplay between hydration and permeability E Sparr, H Wennerström Biophysical journal 81 (2), 1014-1028, 2001 | 105 | 2001 |
| Adsorption of α-synuclein to supported lipid bilayers: positioning and role of electrostatics E Hellstrand, M Grey, ML Ainalem, J Ankner, VT Forsyth, G Fragneto, ... ACS chemical neuroscience 4 (10), 1339-1351, 2013 | 104 | 2013 |
| Skin membrane electrical impedance properties under the influence of a varying water gradient S Björklund, T Ruzgas, A Nowacka, I Dahi, D Topgaard, E Sparr, ... Biophysical journal 104 (12), 2639-2650, 2013 | 95 | 2013 |
| Small polar molecules like glycerol and urea can preserve the fluidity of lipid bilayers under dry conditions A Nowacka, S Douezan, L Wadsö, D Topgaard, E Sparr Soft Matter 8 (5), 1482-1491, 2012 | 91 | 2012 |
