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Ruben Doste
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A rule‐based method to model myocardial fiber orientation in cardiac biventricular geometries with outflow tracts
R Doste, D Soto‐Iglesias, G Bernardino, A Alcaine, R Sebastian, ...
International journal for numerical methods in biomedical engineering 35 (4 …, 2019
1142019
Fully coupled fluid‐electro‐mechanical model of the human heart for supercomputers
A Santiago, J Aguado‐Sierra, M Zavala‐Aké, R Doste‐Beltran, S Gómez, ...
International journal for numerical methods in biomedical engineering 34 (12 …, 2018
1102018
Pharmacological management of hypertrophic cardiomyopathy: from bench to bedside
C Palandri, L Santini, A Argirò, F Margara, R Doste, A Bueno-Orovio, ...
Drugs 82 (8), 889-912, 2022
252022
Smoothed particle hydrodynamics for electrophysiological modeling: an alternative to finite element methods
E Lluch, R Doste, S Giffard-Roisin, A This, M Sermesant, O Camara, ...
Functional Imaging and Modelling of the Heart: 9th International Conference …, 2017
162017
Mechanism based therapies enable personalised treatment of hypertrophic cardiomyopathy
F Margara, Y Psaras, ZJ Wang, M Schmid, R Doste, AC Garfinkel, ...
Scientific reports 12 (1), 22501, 2022
152022
In silico pace-mapping: prediction of left vs. right outflow tract origin in idiopathic ventricular arrhythmias with patient-specific electrophysiological simulations
R Doste, R Sebastian, JF Gomez, D Soto-Iglesias, A Alcaine, L Mont, ...
EP Europace 22 (9), 1419-1430, 2020
142020
Standard quasi-conformal flattening of the right and left atria
M Nuñez-Garcia, G Bernardino, R Doste, J Zhao, O Camara, C Butakoff
Functional Imaging and Modeling of the Heart: 10th International Conference …, 2019
102019
Multiscale modelling of β-adrenergic stimulation in cardiac electromechanical function
R Doste, A Bueno-Orovio
Mathematics 9 (15), 1785, 2021
92021
A rule-based method to model myocardial fiber orientation for simulating ventricular outflow tract arrhythmias
R Doste, D Soto-Iglesias, G Bernardino, R Sebastian, S Giffard-Roisin, ...
Functional Imaging and Modelling of the Heart: 9th International Conference …, 2017
92017
Calibration of a fully coupled electromechanical meshless computational model of the heart with experimental data
È Lluch, O Camara, R Doste, B Bijnens, M De Craene, M Sermesant, ...
Computer Methods in Applied Mechanics and Engineering 364, 112869, 2020
82020
Training machine learning models with synthetic data improves the prediction of ventricular origin in outflow tract ventricular arrhythmias
R Doste, M Lozano, G Jimenez-Perez, L Mont, A Berruezo, D Penela, ...
Frontiers in Physiology 13, 909372, 2022
72022
Ventricular anatomical complexity and sex differences impact predictions from electrophysiological computational models
P Gonzalez-Martin, F Sacco, C Butakoff, R Doste, C Bederian, ...
Plos one 18 (2), e0263639, 2023
52023
Remodelling of potassium currents underlies arrhythmic action potential prolongation under beta-adrenergic stimulation in hypertrophic cardiomyopathy
R Doste, R Coppini, A Bueno-Orovio
Journal of Molecular and Cellular Cardiology 172, 120-131, 2022
52022
Predicting the origin of outflow tract ventricular arrhythmias using machine learning techniques trained with patient-specific electrophysiological simulations
R Doste, M Lozano, JF Gomez, A Alcaine, L Mont, A Berruezo, O Camara, ...
2019 Computing in Cardiology (CinC), Page 1-Page 4, 2019
52019
Digital Twinning of the Human Ventricular Activation Sequence to Clinical 12-lead ECGs and Magnetic Resonance Imaging Using Realistic Purkinje Networks for in Silico Clinical …
J Camps, LA Berg, ZJ Wang, R Sebastian, LL Riebel, R Doste, X Zhou, ...
Medical Image Analysis, 103108, 2024
22024
Electrophysiological mechanisms underlying T wave pseudonormalisation on stress ECGs in hypertrophic cardiomyopathy
JA Coleman, R Doste, M Beltrami, R Coppini, I Olivotto, B Raman, ...
Computers in Biology and Medicine 169, 107829, 2024
22024
Human iPSC-CMs and in-silico technologies define mechanisms and accelerate targeted pharmacogenetics in hypertrophic cardiomyopathy
F Margara, Y Psaras, ZJ Wang, M Schmid, R Doste, A Garfinkel, ...
bioRxiv, 2022.06. 08.495324, 2022
22022
Paradoxical prolongation of QT interval during exercise in patients with hypertrophic cardiomyopathy: cellular mechanisms and implications for diastolic function
R Coppini, M Beltrami, R Doste, A Bueno-Orovio, C Ferrantini, G Vitale, ...
European Heart Journal Open 2 (3), oeac034, 2022
22022
Effects of Fibre Orientation on Electrocardiographic and Mechanical Functions in a Computational Human Biventricular Model
L Wang, ZJ Wang, R Doste, A Santiago, X Zhou, A Quintanas, M Vazquez, ...
International Conference on Functional Imaging and Modeling of the Heart …, 2021
22021
Mechanisms of ischaemia-induced arrhythmias in hypertrophic cardiomyopathy: a large-scale computational study
JA Coleman, R Doste, Z Ashkir, R Coppini, R Sachetto, H Watkins, ...
Cardiovascular Research, cvae086, 2024
2024
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