| Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis SL Spencer, S Gaudet, JG Albeck, JM Burke, PK Sorger Nature 459 (7245), 428-432, 2009 | 1225 | 2009 |
| The proliferation-quiescence decision is controlled by a bifurcation in CDK2 activity at mitotic exit SL Spencer, SD Cappell, FC Tsai, KW Overton, CL Wang, T Meyer Cell 155 (2), 369-383, 2013 | 676 | 2013 |
| Ki67 is a graded rather than a binary marker of proliferation versus quiescence I Miller, M Min, C Yang, C Tian, S Gookin, D Carter, SL Spencer Cell reports 24 (5), 1105-1112. e5, 2018 | 531 | 2018 |
| Measuring and modeling apoptosis in single cells SL Spencer, PK Sorger Cell 144 (6), 926-939, 2011 | 376 | 2011 |
| Modeling a snap-action, variable-delay switch controlling extrinsic cell death JG Albeck, JM Burke, SL Spencer, DA Lauffenburger, PK Sorger PLoS biology 6 (12), e299, 2008 | 362 | 2008 |
| Non-genetic cell-to-cell variability and the consequences for pharmacology M Niepel, SL Spencer, PK Sorger Current opinion in chemical biology 13 (5-6), 556-561, 2009 | 262 | 2009 |
| Irreversible APCCdh1 inactivation underlies the point of no return for cell-cycle entry SD Cappell, M Chung, A Jaimovich, SL Spencer, T Meyer Cell 166 (1), 167-180, 2016 | 245 | 2016 |
| Endogenous replication stress in mother cells leads to quiescence of daughter cells M Arora, J Moser, H Phadke, AA Basha, SL Spencer Cell reports 19 (7), 1351-1364, 2017 | 182 | 2017 |
| Synthesis: cancer research meets evolutionary biology JW Pepper, C Scott Findlay, R Kassen, SL Spencer, CC Maley Evolutionary applications 2 (1), 62-70, 2009 | 145 | 2009 |
| Modeling somatic evolution in tumorigenesis SL Spencer, RA Gerety, KJ Pienta, S Forrest PLoS computational biology 2 (8), e108, 2006 | 140 | 2006 |
| Control of the Restriction Point by Rb and p21 J Moser, I Miller, D Carter, SL Spencer Proceedings of the National Academy of Sciences 115 (35), E8219-E8227, 2018 | 129 | 2018 |
| An ordinary differential equation model for the multistep transformation to cancer SL Spencer, MJ Berryman, JA García, D Abbott Journal of Theoretical Biology 231 (4), 515-524, 2004 | 126 | 2004 |
| A map of protein dynamics during cell-cycle progression and cell-cycle exit S Gookin, M Min, H Phadke, M Chung, J Moser, I Miller, D Carter, ... PLoS biology 15 (9), e2003268, 2017 | 118 | 2017 |
| Basal p21 controls population heterogeneity in cycling and quiescent cell cycle states KW Overton, SL Spencer, WL Noderer, T Meyer, CL Wang Proceedings of the National Academy of Sciences 111 (41), E4386-E4393, 2014 | 116 | 2014 |
| Exploring the contextual sensitivity of factors that determine cell-to-cell variability in receptor-mediated apoptosis S Gaudet, SL Spencer, WW Chen, PK Sorger PLoS computational biology 8 (4), e1002482, 2012 | 112 | 2012 |
| Cells surviving fractional killing by TRAIL exhibit transient but sustainable resistance and inflammatory phenotypes DA Flusberg, J Roux, SL Spencer, PK Sorger Molecular biology of the cell 24 (14), 2186-2200, 2013 | 107 | 2013 |
| Temporal integration of mitogen history in mother cells controls proliferation of daughter cells M Min, Y Rong, C Tian, SL Spencer Science 368 (6496), 1261-1265, 2020 | 102 | 2020 |
| Spontaneously slow-cycling subpopulations of human cells originate from activation of stress-response pathways M Min, SL Spencer PLoS biology 17 (3), e3000178, 2019 | 78 | 2019 |
| Melanoma subpopulations that rapidly escape MAPK pathway inhibition incur DNA damage and rely on stress signalling C Yang, C Tian, TE Hoffman, NK Jacobsen, SL Spencer Nature Communications 12 (1), 1747, 2021 | 67 | 2021 |
| Systematic calibration of a cell signaling network model KA Kim, SL Spencer, JG Albeck, JM Burke, PK Sorger, S Gaudet, DH Kim BMC bioinformatics 11 (1), 202, 2010 | 65 | 2010 |
