עקוב אחר
Usha Viswanathan
Usha Viswanathan
Janssen Scientist, Computer Aided Drug Design
כתובת אימייל מאומתת בדומיין its.jnj.com
כותרת
צוטט על ידי
צוטט על ידי
שנה
Targeting the multifunctional HBV core protein as a potential cure for chronic hepatitis B
U Viswanathan, N Mani, Z Hu, H Ban, Y Du, J Hu, J Chang, JT Guo
Antiviral research 182, 104917, 2020
772020
Identification of a novel inhibitor of dengue virus protease through use of a virtual screening drug discovery Web portal
U Viswanathan, SM Tomlinson, JM Fonner, SA Mock, SJ Watowich
Journal of chemical information and modeling 54 (10), 2816-2825, 2014
562014
Discovery and mechanistic study of a novel human-stimulator-of-interferon-genes agonist
X Zhang, B Liu, L Tang, Q Su, N Hwang, M Sehgal, J Cheng, J Ma, ...
ACS infectious diseases 5 (7), 1139-1149, 2019
502019
Importance of dynamic hydrogen bonds and reorientation barriers in proton transport
C Nagamani, U Viswanathan, C Versek, MT Tuominen, SM Auerbach, ...
Chemical communications 47 (23), 6638-6640, 2011
342011
Vibrational predissociation spectroscopy and theory of Ar-tagged, protonated Imidazole (Im) Im1–3H+· Ar clusters
HK Gerardi, GH Gardenier, U Viswanathan, SM Auerbach, MA Johnson
Chemical Physics Letters 501 (4-6), 172-178, 2011
242011
CpAMs induce assembly of HBV capsids with altered electrophoresis mobility: Implications for mechanism of inhibiting pgRNA packaging
S Wu, Y Luo, U Viswanathan, J Kulp, J Cheng, Z Hu, Q Xu, Y Zhou, ...
Antiviral research 159, 1-12, 2018
212018
Modeling energy landscapes of proton motion in nonaqueous, tethered proton wires
U Viswanathan, D Basak, D Venkataraman, JT Fermann, SM Auerbach
The Journal of Physical Chemistry A 115 (21), 5423-5434, 2011
212011
Modeling proton jumps in HY zeolite: effects of acid site heterogeneity
U Viswanathan, JT Fermann, LK Toy, SM Auerbach, T Vreven, MJ Frisch
The Journal of Physical Chemistry C 111 (49), 18341-18347, 2007
192007
Structure-based design of selective, orally available salt-inducible kinase inhibitors that stimulate bone formation in mice
T Sato, CDC Andrade, SH Yoon, Y Zhao, WJ Greenlee, PC Weber, ...
Proceedings of the National Academy of Sciences 119 (50), e2214396119, 2022
172022
Amino acid residues at core protein dimer-dimer interface modulate multiple steps of hepatitis B virus replication and HBeAg biogenesis
H Liu, J Cheng, U Viswanathan, J Chang, F Lu, JT Guo
PLoS pathogens 17 (11), e1010057, 2021
172021
Profiling the circulating mRNA transcriptome in human liver disease
A Sayeed, BE Dalvano, DE Kaplan, U Viswanathan, J Kulp, AH Janneh, ...
Oncotarget 11 (23), 2216, 2020
142020
Modeling nonaqueous proton wires built from helical peptides: biased proton transfer driven by helical dipoles
GE López, I Colón-Díaz, A Cruz, S Ghosh, SB Nicholls, U Viswanathan, ...
The Journal of Physical Chemistry A 116 (4), 1283-1288, 2012
142012
Simulating hydrogen-bond clustering and phase behaviour of imidazole oligomers
JA Harvey, D Basak, D Venkataraman, SM Auerbach
Molecular Physics 110 (9-10), 957-966, 2012
132012
Identification of hepatitis B virus core protein residues critical for capsid assembly, pgRNA encapsidation and resistance to capsid assembly modulators
Y Luo, J Cheng, Z Hu, H Ban, S Wu, N Hwang, J Kulp, Y Li, Y Du, J Chang, ...
Antiviral Research 191, 105080, 2021
102021
A putative amphipathic alpha helix in hepatitis B virus small envelope protein plays a critical role in the morphogenesis of subviral particles
S Yang, Z Shen, Y Kang, L Sun, U Viswanathan, H Guo, T Zhou, X Dai, ...
Journal of Virology 95 (8), 10.1128/jvi. 02399-20, 2021
52021
4-Oxooctahydroquinoline-1 (2H)-carboxamides as hepatitis B virus (HBV) capsid core protein assembly modulators
N Hwang, H Ban, S Wu, K McGuire, E Hernandez, J Chen, Q Zhao, ...
Bioorganic & medicinal chemistry letters 58, 128518, 2022
42022
Precision Discovery of Novel Inhibitors of Human Cancer Target HsMetAP1 from Vast Unexplored Metagenomic Diversity
OW Liu, S Akers, G Alvarez, S Brown, W Cai, Z Charlop-Powers, ...
bioRxiv, 2022.06. 11.495772, 2022
12022
Small-molecule inhibitors of dengue virus proteases
SJ Watowich, U Viswanathan
US Patent 9,408,813, 2016
12016
Identification of novel tetrahydroquinoxaline derived phenyl ureas as modulators of the hepatitis B virus nucleocapsid assembly
N Hwang, S Wu, H Ban, H Luo, J Ma, J Cheng, Q Zhao, JA Laney, N Du, ...
European Journal of Medicinal Chemistry 259, 115634, 2023
2023
Molecular modeling of proton transfer mechanisms, energetics and rates in zeolites and proton exchange membranes
U Viswanathan
University of Massachusetts Amherst, 2011
2011
המערכת אינה יכולה לבצע את הפעולה כעת. נסה שוב מאוחר יותר.
מאמרים 1–20