|Insulin signaling to the glomerular podocyte is critical for normal kidney function|
GI Welsh, LJ Hale, V Eremina, M Jeansson, Y Maezawa, R Lennon, ...
Cell metabolism 12 (4), 329-340, 2010
|Insulin-like growth factors and kidney disease|
LA Bach, LJ Hale
American Journal of Kidney Diseases 65 (2), 327-336, 2015
|Evaluation of variability in human kidney organoids|
B Phipson, P X. Er, AN Combes, TA Forbes, SE Howden, L Zappia, ...
Nature Methods, 2018
|Patient-iPSC-Derived Kidney Organoids Show Functional Validation of a Ciliopathic Renal Phenotype and Reveal Underlying Pathogenetic Mechanisms|
T Forbes, S Howden, K Lawlor, B Phipson, L Hale, S Wilson, C Quinlan, ...
The American Journal of Human Genetics, 2018
|Insulin directly stimulates VEGF-A production in the glomerular podocyte|
LJ Hale, J Hurcombe, A Lay, B Santamaría, AM Valverde, MA Saleem, ...
American journal of physiology-Renal physiology 305 (2), F182-F188, 2013
|3D organoid-derived human glomeruli for personalised podocyte disease modelling and drug screening|
LJ Hale, SE Howden, B Phipson, A Lonsdale, P X.Er, I Ghobrial, S Hosawi, ...
Nature Communications 9 (Article number: 5167), 2018
|Insulin signalling to the kidney in health and disease|
LJ Hale, RJM Coward
Clinical science 124 (6), 351-370, 2013
|The insulin receptor and the kidney|
LJ Hale, RJM Coward
Current opinion in nephrology and hypertension 22 (1), 100-106, 2013
|IRS2 and PTEN are key molecules in controlling insulin sensitivity in podocytes|
B Santamaria, E Marquez, A Lay, RMM Carew, Á González-Rodríguez, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1853 (12), 3224-3234, 2015
|Insulin‐like growth factor‐II is produced by, signals to and is an important survival factor for the mature podocyte in man and mouse|
LJ Hale, GI Welsh, CM Perks, JA Hurcombe, S Moore, I Hers, MA Saleem, ...
The Journal of pathology 230 (1), 95-106, 2013
|Genetic deletion of cell division autoantigen 1 retards diabetes-associated renal injury|
Z Chai, A Dai, Y Tu, J Li, T Wu, Y Wang, LJ Hale, F Koentgen, MC Thomas, ...
Journal of the American Society of Nephrology 24 (11), 1782-1792, 2013
|Generating Kidney from Stem Cells|
MH Little, LJ Hale, SE Howden, SV Kumar
Annual Review of Physiology 81, 335–357, 2019
|Bioprinted pluripotent stem cell-derived kidney organoids provide opportunities for high content screening|
JW Higgins, A Chambon, K Bishard, A Hartung, D Arndt, J Brugnano, ...
bioRxiv, 505396, 2018
|Transcriptional evaluation of the developmental accuracy, reproducibility and robustness of kidney organoids derived from human pluripotent stem cells|
B Phipson, XE Pei, L Hale, D Yen, K Lawlor, M Takasato, J Sun, ...
bioRxiv, 238428, 2017
|Cellular extrusion bioprinting improves kidney organoid reproducibility and conformation|
KT Lawlor, JM Vanslambrouck, JW Higgins, A Chambon, K Bishard, ...
Nature Biomaterials 63, 2020
|Shining a Light on Alport Syndrome|
L Hale, M Little
Cell Chemical Biology 25 (5), 497-498, 2018
|The roles of insulin and insulin-like growth factors in the podocyte cells of the kidney|
University of Bristol, 2011