| Antibiotics induce redox-related physiological alterations as part of their lethality DJ Dwyer*, PA Belenky*, JH Yang*, IC MacDonald, JD Martell, ... Proceedings of the National Academy of Sciences 111 (20), E2100-E2109, 2014 | 511 | 2014 |
| Antibiotic efficacy is linked to bacterial cellular respiration MA Lobritz*, P Belenky*, CBM Porter, A Gutierrez, JH Yang, EG Schwarz, ... Proceedings of the National Academy of Sciences, 201509743, 2015 | 349 | 2015 |
| Carbon Sources Tune Antibiotic Susceptibility in Pseudomonas aeruginosa via Tricarboxylic Acid Cycle Control S Meylan, CBM Porter*, JH Yang*, P Belenky, A Gutierrez, MA Lobritz, ... Cell Chemical Biology, 2017 | 149 | 2017 |
| Regulation of nuclear PKA revealed by spatiotemporal manipulation of cyclic AMP V Sample*, LM DiPilato*, JH Yang*, Q Ni, JJ Saucerman, J Zhang, ... Nature chemical biology 8 (4), 375-382, 2012 | 113 | 2012 |
| Antibiotic-Induced Changes to the Host Metabolic Environment Inhibit Drug Efficacy and Alter Immune Function JH Yang*, P Bhargava*, D McCloskey, N Mao, BO Palsson, JJ Collins Cell Host & Microbe, 2017 | 103 | 2017 |
| A white-box machine learning approach for revealing antibiotic mechanisms of action JH Yang, SN Wright, M Hamblin, D McCloskey, MA Alcantar, ... Cell 177 (6), 1649-1661. e9, 2019 | 81 | 2019 |
| Comparing McRoberts' and Rubin's maneuvers for initial management of shoulder dystocia: an objective evaluation ED Gurewitsch, EJ Kim, JH Yang, KE Outland, MK McDonald, RH Allen American journal of obstetrics and gynecology 192 (1), 153-160, 2005 | 66 | 2005 |
| Antibiotic efficacy—context matters JH Yang*, SC Bening*, JJ Collins Current Opinion in Microbiology 39, 73-80, 2017 | 56 | 2017 |
| Computational models reduce complexity and accelerate insight into cardiac signaling networks JH Yang, JJ Saucerman Circulation research 108 (1), 85-97, 2011 | 52 | 2011 |
| PKA catalytic subunit compartmentation regulates contractile and hypertrophic responses to β-adrenergic signaling JH Yang, RK Polanowska-Grabowska, JS Smith, CW Shields IV, ... Journal of molecular and cellular cardiology 66, 83-93, 2014 | 45 | 2014 |
| Bacterial metabolic state more accurately predicts antibiotic lethality than growth rate AJ Lopatkin, JM Stokes, EJ Zheng, JH Yang, MK Takahashi, L You, ... Nature Microbiology 4 (12), 2109-2117, 2019 | 43 | 2019 |
| Phospholemman is a negative feed-forward regulator of Ca2+ in β-adrenergic signaling, accelerating β-adrenergic inotropy JH Yang, JJ Saucerman Journal of molecular and cellular cardiology 52 (5), 1048-1055, 2012 | 34 | 2012 |
| Lethality of MalE-LacZ hybrid protein shares mechanistic attributes with oxidative component of antibiotic lethality N Takahashi*, CC Gruber*, JH Yang, X Liu, D Braff, CN Yashaswini, ... Proceedings of the National Academy of Sciences, 201707466, 2017 | 21 | 2017 |
| Simulating complicated human birth for research and training EJ Kim, RH Allen, JH Yang, MK McDonald, W Tam, ED Gurewitsch The 26th Annual International Conference of the IEEE Engineering in Medicine …, 2004 | 14 | 2004 |
| Systems analysis of small signaling modules relevant to eight human diseases KF Benedict, F Mac Gabhann*, RK Amanfu*, AK Chavali*, ... Annals of biomedical engineering 39 (2), 621-635, 2011 | 12 | 2011 |
| Clinically relevant mutations in core metabolic genes confer antibiotic resistance AJ Lopatkin, SC Bening, AL Manson, JM Stokes, MA Kohanski, ... Science 371 (6531), 2021 | 3 | 2021 |
| Applications of machine learning to the problem of antimicrobial resistance: An emerging model for translational research MN Anahtar, JH Yang, S Kanjilal Journal of Clinical Microbiology, JCM. 01260-20, 2021 | 1 | 2021 |
| An objective evaluation of McRoberts' and Rubin's maneuvers for shoulder dystocia E Gurewitsch, E Kim, J Yang, K Outland, R Allen American Journal of Obstetrics & Gynecology 189 (6), S208, 2003 | 1 | 2003 |
| Facing the Upcoming of Multidrug-Resistant and Extensively Drug-Resistant Bacteria: Novel Antimicrobial Therapies (NATs) A León-Buitimea, JR Morones-Ramírez, JH Yang, R Peña-Miller Frontiers in Bioengineering and Biotechnology 9, 126, 2021 | | 2021 |
| Methods for Experimental Evolution of Natural and Synthetic Microbes CJ Bashor, JHY Yang, A Gutierrez, WS Ahn, JJ Collins, BG Wong, ... US Patent App. 16/081,975, 2020 | | 2020 |
James J CollinsMIT; Wyss Institute, Harvard; Broad Institute of MIT & HarvardVerified email at mit.edu
