Unlocking the potential of asymmetric hydrogenation at Merck CS Shultz, SW Krska Accounts of chemical research 40 (12), 1320-1326, 2007 | 201 | 2007 |
Kinetic studies of migratory insertion reactions at the (1, 3-bis (diphenylphosphino) propane) Pd (II) center and their relationship to the alternating copolymerization of … CS Shultz, J Ledford, JM DeSimone, M Brookhart Journal of the American Chemical Society 122 (27), 6351-6356, 2000 | 139 | 2000 |
Bond Angle Effects on the Migratory Insertion of Ethylene and Carbon Monoxide into Palladium (II)− Methyl Bonds in Complexes Bearing Bidentate Phosphine Ligands J Ledford, CS Shultz, DP Gates, PS White, JM DeSimone, M Brookhart Organometallics 20 (25), 5266-5276, 2001 | 119 | 2001 |
An efficient catalyst for Pd-catalyzed carbonylation of aryl arenesulfonates C Cai, NR Rivera, J Balsells, RR Sidler, JC McWilliams, CS Shultz, Y Sun Organic letters 8 (22), 5161-5164, 2006 | 78 | 2006 |
Convergent, kilogram scale synthesis of an Akt kinase inhibitor P Grongsaard, PG Bulger, DJ Wallace, L Tan, Q Chen, SJ Dolman, ... Organic Process Research & Development 16 (5), 1069-1081, 2012 | 68 | 2012 |
New efficient asymmetric synthesis of taranabant, a cb1r inverse agonist for the treatment of obesity DJ Wallace, KR Campos, CS Shultz, A Klapars, D Zewge, BR Crump, ... Organic Process Research & Development 13 (1), 84-90, 2009 | 67 | 2009 |
Cationic Four-and Five-Coordinate Nickel (II) Complexes: Insights into the Nickel (II)-Catalyzed Copolymerization of Ethylene and Carbon Monoxide CS Shultz, JM DeSimone, M Brookhart Organometallics 20 (1), 16-18, 2001 | 64 | 2001 |
Asymmetric Hydrogenation of N-Sulfonylated-α-dehydroamino Acids: Toward the Synthesis of an Anthrax Lethal Factor Inhibitor CS Shultz, SD Dreher, N Ikemoto, JM Williams, EJJ Grabowski, SW Krska, ... Organic Letters 7 (16), 3405-3408, 2005 | 55 | 2005 |
Four- and Five-Coordinate CO Insertion Mechanisms in d8-Nickel(II) Complexes CS Shultz, JM DeSimone, M Brookhart Journal of the American Chemical Society 123 (37), 9172-9173, 2001 | 52 | 2001 |
Palladium-Catalyzed Carbon Isotope Exchange on Aliphatic and Benzoic Acid Chlorides DR Gauthier Jr, NR Rivera, H Yang, DM Schultz, CS Shultz Journal of the American Chemical Society 140 (46), 15596-15600, 2018 | 51 | 2018 |
Highly enantioselective synthesis of anti aryl β-hydroxy α-amino esters via DKR transfer hydrogenation Z Liu, CS Shultz, CA Sherwood, S Krska, PG Dormer, R Desmond, C Lee, ... Tetrahedron letters 52 (14), 1685-1688, 2011 | 47 | 2011 |
Practical Synthesis of a Potent Bradykinin B1 Antagonist via Enantioselective Hydrogenation of a Pyridyl N-Acyl Enamide PD O’Shea, D Gauvreau, F Gosselin, G Hughes, C Nadeau, A Roy, ... The Journal of organic chemistry 74 (12), 4547-4553, 2009 | 39 | 2009 |
From high-throughput catalyst screening to reaction optimization: Detailed investigation of regioselective Suzuki coupling of 1, 6-naphthyridone dichloride C Cai, JYL Chung, JC McWilliams, Y Sun, CS Shultz, M Palucki Organic process research & development 11 (3), 328-335, 2007 | 36 | 2007 |
Synthesis of a tertiary carbinamide via a novel Rh-catalyzed asymmetric hydrogenation J Limanto, CS Shultz, B Dorner, RA Desmond, PN Devine, SW Krska The Journal of organic chemistry 73 (4), 1639-1642, 2008 | 25 | 2008 |
Preparation of 4-Allylisoindoline via a Kumada Coupling with Allylmagnesium Chloride MJ Zacuto, CS Shultz, M Journet Organic Process Research & Development 15 (1), 158-161, 2011 | 22* | 2011 |
A [2+ 2] Cycloaddition Route to Dimethylaminomethylene Vinamidinium Salts IW Davies, DM Tellers, CS Shultz, FJ Fleitz, D Cai, Y Sun Organic letters 4 (17), 2969-2972, 2002 | 19 | 2002 |
Crystal forms of a HCV protease inhibitor GL Beutner, RM Wenslow Jr, EJ Choi, CS Shultz, J Scott, JD Arredondo, ... US Patent 9,242,917, 2016 | 17 | 2016 |
Formation of tetra-substituted enamides and stereoselective reduction thereof KR Campos, A Klapars, JC McWilliams, CS Shultz, DJ Wallace, AM Chen, ... US Patent 7,629,470, 2009 | 9 | 2009 |
Enabling Asymmetric Hydrogenation for the Design of Efficient Synthesis of Drug Substances Y Sun, S Krska, CS Shultz, DM Tellers Asymmetric Catalysis on Industrial Scale: Challenges, Approaches and …, 2010 | 5 | 2010 |
Catalytic asymmetric hydrogenation to access spiroindane dimethyl acetic acid S He, CS Shultz, Z Lai, R Eid, PH Dobbelaar, Z Ye, RP Nargund Tetrahedron letters 52 (28), 3621-3624, 2011 | 4 | 2011 |