| Asymmetric synthesis of telcagepant, a CGRP receptor antagonist for the treatment of migraine F Xu, M Zacuto, N Yoshikawa, R Desmond, S Hoerrner, T Itoh, M Journet, ... The Journal of Organic Chemistry 75 (22), 7829-7841, 2010 | 109 | 2010 |
| Total synthesis of (−)-CP-263,114 (Phomoidride B) N Waizumi, T Itoh, T Fukuyama Journal of the American Chemical Society 122 (32), 7825-7826, 2000 | 108 | 2000 |
| Engineered ribosyl-1-kinase enables concise synthesis of molnupiravir, an antiviral for COVID-19 JA McIntosh, T Benkovics, SM Silverman, MA Huffman, J Kong, ... ACS Central Science 7 (12), 1980-1985, 2021 | 100 | 2021 |
| Synthetic studies on CP-225,917 and CP-263,114 N Waizumi, T Itoh, T Fukuyama Tetrahedron letters 39 (33), 6015-6018, 1998 | 75 | 1998 |
| Highly efficient synthesis of HIV NNRTI doravirine DR Gauthier Jr, BD Sherry, Y Cao, M Journet, G Humphrey, T Itoh, ... Organic letters 17 (6), 1353-1356, 2015 | 43 | 2015 |
| A new synthetic route to phomoidride B and its derivatives Y Hayashi, T Itoh, T Fukuyama Organic Letters 5 (13), 2235-2238, 2003 | 34 | 2003 |
| Synthetic approach to tetrodotoxin T Itoh, M Watanabe, T Fukuyama Synlett 2002 (08), 1323-1325, 2002 | 31 | 2002 |
| Electrochemical recycling of adenosine triphosphate in biocatalytic reaction cascades S Ruccolo, G Brito, M Christensen, T Itoh, K Mattern, K Stone, ... Journal of the American Chemical Society 144 (49), 22582-22588, 2022 | 20 | 2022 |
| New semi-automated computer-based system for assessing the purge of mutagenic impurities MJ Burns, MA Ott, A Teasdale, SA Stalford, V Antonucci, JC Baumann, ... Organic process research & development 23 (11), 2470-2481, 2019 | 19 | 2019 |
| Utilizing biocatalysis and a sulfolane-mediated reductive acetal opening to access nemtabrutinib from cyrene N Kuhl, BWH Turnbull, Y Ji, RT Larson, M Shevlin, CK Prier, CK Chung, ... Green Chemistry 25 (2), 606-613, 2023 | 13 | 2023 |
| Development of a Practical Manufacturing Process to Relebactam via Thorough Understanding of the Origin and Control of Oligomeric Impurities J Kim, T Itoh, F Xu, ZEX Dance, JH Waldman, DJ Wallace, F Wu, ... Organic Process Research & Development 25 (10), 2249-2259, 2021 | 4 | 2021 |
| Process for making reverse transcriptase inhibitors Y Cao, DR Gauthier Jr, GR Humphrey, T Itoh, M Journet, G Qian, ... US Patent 9,598,397, 2017 | 3 | 2017 |
| Synthesis of Fused Oxepane HIV Integrase Inhibitor MK-1376 PE Maligres, ZJ Song, NA Strotman, J Yin, T Pei, HR Strotman, T Itoh, ... Synthesis 52 (22), 3378-3388, 2020 | 2 | 2020 |
| Process for making reverse transcriptase inhibitors T Itoh, I Jeon, I Mangion, G Qian, BD Sherry, DR Gauthier, Y Cao US Patent 9,663,490, 2017 | 2 | 2017 |
| Directed Evolution to Reverse Epoxide Hydrolase Enantioselectivity for meso‐3,4‐Epoxytetrahydrofuran K Hiraga, T Itoh, D Verma, W Wang, C Huang, M Ardolino, YL Zhong, ... ChemCatChem 15 (12), e202300238, 2023 | 1 | 2023 |
| Process for making tetracyclic heterocycle compounds H Li, J Yin, KM Belyk, KR Campos, Q Chen, AM Hyde, T Itoh, A Klapars, ... US Patent 10,202,401, 2019 | 1 | 2019 |
| Synthesis of antiviral nucleosides T Benkovics, PS Fier, A Fryszkowska, MA Huffman, T Itoh, J Kong, ... US Patent App. 18/256,058, 2024 | | 2024 |
| PROCESS FOR THE PREPARATION OF INTERMEDIATES USEFUL FOR MAKING (2S, 5R)-7-OXO-N-PIPERIDIN-4-YL-6-(SULFOXY)-l, 6-DIAZABICYCLO [3.2. 1] OCTANE-2-CARBOXAMIDE JYL Chung, T Itoh, J Kim, JH Waldman, DJ Wallace, A Wood, F Xu, ... US Patent App. 17/604,525, 2022 | | 2022 |
| Process for preparing substituted tetracyclic heterocycle compounds J Yin, T Itoh, J Yin, B Xiang, KR Campos, A Kalinin, Z Liu, MD Christensen, ... US Patent 10,457,690, 2019 | | 2019 |
| Process for making tetracyclic heterocycle compounds H Li, J Yin, KM Belyk, KR Campos, Q Chen, AM Hyde, T Itoh, A Klapars, ... US Patent App. 15/325,392, 2017 | | 2017 |
