Quantitative phosphoproteomics reveal mTORC1 activates de novo pyrimidine synthesis AM Robitaille, S Christen, M Shimobayashi, M Cornu, LL Fava, S Moes, ... Science 339 (6125), 1320-1323, 2013 | 556 | 2013 |
Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly YW Chan, LL Fava, A Uldschmid, MHA Schmitz, DW Gerlich, EA Nigg, ... Journal of cell biology 185 (5), 859-874, 2009 | 184 | 2009 |
The PIDDosome activates p53 in response to supernumerary centrosomes LL Fava, F Schuler, V Sladky, MD Haschka, C Soratroi, L Eiterer, ... Genes & development 31 (1), 34-45, 2017 | 174 | 2017 |
The NOXA–MCL1–BIM axis defines lifespan on extended mitotic arrest MD Haschka, C Soratroi, S Kirschnek, G Häcker, R Hilbe, S Geley, ... Nature communications 6 (1), 6891, 2015 | 107 | 2015 |
Caspase-2 at a glance LL Fava, FJ Bock, S Geley, A Villunger Journal of cell science 125 (24), 5911-5915, 2012 | 107 | 2012 |
Perturbing mitosis for anti‐cancer therapy: is cell death the only answer? M Haschka, G Karbon, LL Fava, A Villunger EMBO reports 19 (3), e45440, 2018 | 99 | 2018 |
Probing the in vivo function of Mad1: C‐Mad2 in the spindle assembly checkpoint LL Fava, M Kaulich, EA Nigg, A Santamaria The EMBO journal 30 (16), 3322-3336, 2011 | 88 | 2011 |
RIPK1 and caspase-8 ensure chromosome stability independently of their role in cell death and inflammation G Liccardi, LR Garcia, T Tenev, A Annibaldi, AJ Legrand, D Robertson, ... Molecular cell 73 (3), 413-428. e7, 2019 | 61 | 2019 |
Evaluation of data-dependent and-independent mass spectrometric workflows for sensitive quantification of proteins and phosphorylation sites M Bauer, E Ahrné, AP Baron, T Glatter, LL Fava, A Santamaria, EA Nigg, ... Journal of proteome research 13 (12), 5973-5988, 2014 | 58 | 2014 |
E2F-family members engage the PIDDosome to limit hepatocyte ploidy in liver development and regeneration VC Sladky, K Knapp, C Soratroi, J Heppke, F Eichin, L Rocamora-Reverte, ... Developmental cell 52 (3), 335-349. e7, 2020 | 53 | 2020 |
Centriolar distal appendages activate the centrosome‐PIDDosome‐p53 signalling axis via ANKRD26 M Burigotto, A Mattivi, D Migliorati, G Magnani, C Valentini, M Roccuzzo, ... The EMBO journal 40 (4), e104844, 2021 | 48 | 2021 |
The resurrection of the PIDDosome–emerging roles in the DNA-damage response and centrosome surveillance V Sladky, F Schuler, LL Fava, A Villunger Journal of cell science 130 (22), 3779-3787, 2017 | 41 | 2017 |
Death of p53-defective cells triggered by forced mitotic entry in the presence of DNA damage is not uniquely dependent on Caspase-2 or the PIDDosome C Manzl, LL Fava, G Krumschnabel, L Peintner, MC Tanzer, C Soratroi, ... Cell death & disease 4 (12), e942-e942, 2013 | 39 | 2013 |
p53 mitotic centrosome localization preserves centrosome integrity and works as sensor for the mitotic surveillance pathway C Contadini, L Monteonofrio, I Virdia, A Prodosmo, D Valente, L Chessa, ... Cell death & disease 10 (11), 850, 2019 | 34 | 2019 |
GTP regulates the microtubule nucleation activity of γ-tubulin L Gombos, A Neuner, M Berynskyy, LL Fava, RC Wade, C Sachse, ... Nature cell biology 15 (11), 1317-1327, 2013 | 33 | 2013 |
CRISPR/Cas9 ribonucleoprotein-mediated knockin generation in hTERT-RPE1 cells S Ghetti, M Burigotto, A Mattivi, G Magnani, A Casini, A Bianchi, ... STAR protocols 2 (2), 100407, 2021 | 14 | 2021 |
Allele-specific genomic data elucidate the role of somatic gain and copy-number neutral loss of heterozygosity in cancer Y Ciani, T Fedrizzi, D Prandi, F Lorenzin, A Locallo, P Gasperini, ... Cell Systems 13 (2), 183-193. e7, 2022 | 13 | 2022 |
The PIDDosome: centrosome guardian and backup on the DNA damage response M Burigotto, LL Fava Molecular & Cellular Oncology 8 (3), 1893625, 2021 | 9 | 2021 |
Loss-of-Function but Not Gain-of-Function Properties of Mutant TP53 Are Critical for the Proliferation, Survival, and Metastasis of a Broad Range of Cancer Cells Z Wang, M Burigotto, S Ghetti, F Vaillant, T Tan, BD Capaldo, M Palmieri, ... Cancer Discovery 14 (2), 362-379, 2024 | 8 | 2024 |
Beclin 1 is dispensable for chromosome congression and proper outer kinetochore assembly LL Fava, J Rainer, MD Haschka, S Geley, A Villunger EMBO reports 16 (10), 1233-1236, 2015 | 8 | 2015 |