| Identification of a lipokine, a lipid hormone linking adipose tissue to systemic metabolism H Cao, K Gerhold, JR Mayers, MM Wiest, SM Watkins, GS Hotamisligil Cell 134 (6), 933-944, 2008 | 1261 | 2008 |
| Elevation of circulating branched-chain amino acids is an early event in human pancreatic adenocarcinoma development JR Mayers, C Wu, CB Clish, P Kraft, ME Torrence, BP Fiske, C Yuan, ... Nature medicine 20 (10), 1193-1198, 2014 | 639 | 2014 |
| Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis E Erbay, VR Babaev, JR Mayers, L Makowski, KN Charles, ME Snitow, ... Nature medicine 15 (12), 1383-1391, 2009 | 569 | 2009 |
| Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers JR Mayers, ME Torrence, LV Danai, T Papagiannakopoulos, ... Science 353 (6304), 1161-1165, 2016 | 530 | 2016 |
| Reductive glutamine metabolism is a function of the α-ketoglutarate to citrate ratio in cells SM Fendt, EL Bell, MA Keibler, BA Olenchock, JR Mayers, TM Wasylenko, ... Nature communications 4 (1), 2236, 2013 | 374 | 2013 |
| Collagen-derived proline promotes pancreatic ductal adenocarcinoma cell survival under nutrient limited conditions O Olivares, JR Mayers, V Gouirand, ME Torrence, T Gicquel, L Borge, ... Nature communications 8 (1), 16031, 2017 | 344 | 2017 |
| Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors SM Davidson, O Jonas, MA Keibler, HW Hou, A Luengo, JR Mayers, ... Nature medicine 23 (2), 235-241, 2017 | 299 | 2017 |
| Transaminase inhibition by 2-hydroxyglutarate impairs glutamate biosynthesis and redox homeostasis in glioma SK McBrayer, JR Mayers, GJ DiNatale, DD Shi, J Khanal, AA Chakraborty, ... Cell 175 (1), 101-116. e25, 2018 | 272 | 2018 |
| Adipocyte lipid chaperone AP2 is a secreted adipokine regulating hepatic glucose production H Cao, M Sekiya, ME Ertunc, MF Burak, JR Mayers, A White, K Inouye, ... Cell metabolism 17 (5), 768-778, 2013 | 260 | 2013 |
| Metformin decreases glucose oxidation and increases the dependency of prostate cancer cells on reductive glutamine metabolism SM Fendt, EL Bell, MA Keibler, SM Davidson, GJ Wirth, B Fiske, ... Cancer research 73 (14), 4429-4438, 2013 | 236 | 2013 |
| Famine versus feast: understanding the metabolism of tumors in vivo JR Mayers, MG Vander Heiden Trends in biochemical sciences 40 (3), 130-140, 2015 | 191 | 2015 |
| Altered exocrine function can drive adipose wasting in early pancreatic cancer LV Danai, A Babic, MH Rosenthal, EA Dennstedt, A Muir, EC Lien, ... Nature 558 (7711), 600-604, 2018 | 127 | 2018 |
| Nature and nurture: what determines tumor metabolic phenotypes? JR Mayers, MG Vander Heiden Cancer research 77 (12), 3131-3134, 2017 | 70 | 2017 |
| Dissecting cell-type-specific metabolism in pancreatic ductal adenocarcinoma AN Lau, Z Li, LV Danai, AM Westermark, AM Darnell, R Ferreira, ... Elife 9, e56782, 2020 | 69 | 2020 |
| Resveratrol treatment in mice does not elicit the bradycardia and hypothermia associated with calorie restriction JR Mayers, BW Iliff, SJ Swoap The FASEB Journal 23 (4), 1032, 2009 | 53 | 2009 |
| Circulating metabolites and survival among patients with pancreatic cancer C Yuan, CB Clish, C Wu, JR Mayers, P Kraft, MK Townsend, M Zhang, ... Journal of the National Cancer Institute 108 (6), djv409, 2016 | 36 | 2016 |
| Gut microbial metabolism of 5-ASA diminishes its clinical efficacy in inflammatory bowel disease RS Mehta, JR Mayers, Y Zhang, A Bhosle, NR Glasser, LH Nguyen, W Ma, ... Nature Medicine 29 (3), 700-709, 2023 | 35 | 2023 |
| Model systems to study the chronic, polymicrobial infections in cystic fibrosis: current approaches and exploring future directions GA O’Toole, A Crabbé, R Kümmerli, JJ LiPuma, JM Bomberger, ... MBio 12 (5), 10.1128/mbio. 01763-21, 2021 | 29 | 2021 |
| Ketogenic HMG‐CoA lyase and its product β‐hydroxybutyrate promote pancreatic cancer progression V Gouirand, T Gicquel, EC Lien, E Jaune‐Pons, Q Da Costa, P Finetti, ... The EMBO journal 41 (9), e110466, 2022 | 28 | 2022 |
| BCAT1 defines gliomas by IDH status JR Mayers, MG Vander Heiden Nature medicine 19 (7), 816-817, 2013 | 25 | 2013 |
