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Ryan K Spencer
Ryan K Spencer
Protomer Technologies, a wholly-owned subsidiary of Eli Lilly and company
Verified email at uci.edu
Title
Cited by
Cited by
Year
X-ray Crystallographic Structures of Trimers and Higher-Order Oligomeric Assemblies of a Peptide Derived from Aβ17–36
RK Spencer, H Li, JS Nowick
Journal of the American Chemical Society 136 (15), 5595-5598, 2014
952014
X-ray Crystallographic Structures of a Trimer, Dodecamer, and Annular Pore Formed by an Aβ17–36 β-Hairpin
AG Kreutzer, IL Hamza, RK Spencer, JS Nowick
Journal of the American Chemical Society 138 (13), 4634-4642, 2016
812016
Electronic conductivity in biomimetic α-helical peptide nanofibers and gels
NL Ing, RK Spencer, SH Luong, HD Nguyen, AI Hochbaum
ACS nano 12 (3), 2652-2661, 2018
802018
Stabilization, assembly, and toxicity of trimers derived from Aβ
AG Kreutzer, S Yoo, RK Spencer, JS Nowick
Journal of the American Chemical Society 139 (2), 966-975, 2017
662017
X-ray crystallographic structure of oligomers formed by a toxic β-hairpin derived from α-synuclein: trimers and higher-order oligomers
PJ Salveson, RK Spencer, JS Nowick
Journal of the American Chemical Society 138 (13), 4458-4467, 2016
642016
Sequence-dependent self-assembly and structural diversity of islet amyloid polypeptide-derived β-sheet fibrils
ST Wang, Y Lin, RK Spencer, MR Thomas, AI Nguyen, N Amdursky, ...
ACS nano 11 (9), 8579-8589, 2017
572017
Universal Relationship between Molecular Structure and Crystal Structure in Peptoid Polymers and Prevalence of the cis Backbone Conformation
DR Greer, MA Stolberg, J Kundu, RK Spencer, T Pascal, D Prendergast, ...
Journal of the American Chemical Society 140 (2), 827-833, 2018
552018
Cooperative Intramolecular Hydrogen Bonding Strongly Enforces cis-Peptoid Folding
AW Wijaya, AI Nguyen, LT Roe, GL Butterfoss, RK Spencer, NK Li, ...
Journal of the American Chemical Society 141 (49), 19436-19447, 2019
522019
Atomic-level engineering and imaging of polypeptoid crystal lattices
S Xuan, X Jiang, RK Spencer, NK Li, D Prendergast, NP Balsara, ...
Proceedings of the National Academy of Sciences 116 (45), 22491-22499, 2019
512019
Conformations of peptoids in nanosheets result from the interplay of backbone energetics and intermolecular interactions
JR Edison, RK Spencer, GL Butterfoss, BC Hudson, AI Hochbaum, ...
Proceedings of the National Academy of Sciences 115 (22), 5647-5651, 2018
482018
A fibril-like assembly of oligomers of a peptide derived from β-amyloid
JD Pham, RK Spencer, KH Chen, JS Nowick
Journal of the American Chemical Society 136 (36), 12682-12690, 2014
452014
Recipe for β‐Sheets: Foldamers Containing Amyloidogenic Peptide Sequences
R Spencer, KH Chen, G Manuel, JS Nowick
European Journal of Organic Chemistry 2013 (17), 3523-3528, 2013
372013
A newcomer′ s guide to peptide crystallography
RK Spencer, JS Nowick
Israel journal of chemistry 55 (6‐7), 698-710, 2015
342015
Evidence for cis Amide Bonds in Peptoid Nanosheets
BC Hudson, A Battigelli, MD Connolly, J Edison, RK Spencer, S Whitelam, ...
The journal of physical chemistry letters 9 (10), 2574-2578, 2018
322018
X-ray Crystallographic Structures of Oligomers of Peptides Derived from β2-Microglobulin
RK Spencer, AG Kreutzer, PJ Salveson, H Li, JS Nowick
Journal of the American Chemical Society 137 (19), 6304-6311, 2015
302015
Heterodivalent linked macrocyclic β-sheets with enhanced activity against Aβ aggregation: two sites are better than one
PN Cheng, R Spencer, RJ Woods, CG Glabe, JS Nowick
Journal of the American Chemical Society 134 (34), 14179-14184, 2012
292012
X-ray Crystallographic Structure of a Compact Dodecamer from a Peptide Derived from Aβ16–36
PJ Salveson, RK Spencer, AG Kreutzer, JS Nowick
Organic letters 19 (13), 3462-3465, 2017
282017
Stereochemistry of polypeptoid chain configurations
RK Spencer, GL Butterfoss, JR Edison, JR Eastwood, S Whitelam, ...
Biopolymers 110 (6), e23266, 2019
272019
A Hexamer of a Peptide Derived from Aβ16–36
AG Kreutzer, RK Spencer, KJ McKnelly, S Yoo, IL Hamza, PJ Salveson, ...
Biochemistry 56 (45), 6061-6071, 2017
262017
A bio-inspired approach to ligand design: folding single-chain peptoids to chelate a multimetallic cluster
AI Nguyen, RK Spencer, CL Anderson, RN Zuckermann
Chemical science 9 (47), 8806-8813, 2018
242018
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